Arnold World June 2023
Mechanism and Dynamics of Photodecarboxylation Catalyzed by Lactate Monooxygenase
Reversing the Enantioselectivity of Enzymatic Carbene N-H Insertion Through Mechanism-Guided Protein Engineering
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Alonosphere June 2023
The global human day
Autotrophic growth of E. coli is achieved by a small number of genetic changes
Single-cell biology: what does the future hold?
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BØPosphere – June 2023
Systems biology of competency in Vibrio natriegens is revealed by applying novel data analytics to the transcriptome
Literate programming for iterative design-build-test-learn cycles in bioengineering
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RabLab May 2023
Impact of acute stress on murine metabolomics and metabolic flux
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Arnold World May 2023
Self-driving laboratories to autonomously navigate the protein fitness landscape
DeCOIL: Optimization of Degenerate Codon Libraries for Machine Learning-Assisted Protein Engineering
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BØPosphere – May 2023
Metabolic homeostasis and growth in abiotic cells
Complete integration of carbene-transfer chemistry into biosynthesis
StressME: unified computing framework of Escherichia coli metabolism, gene expression, and stress responses
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Alonosphere May 2023
Pregnancy and postpartum dynamics revealed by an atlas of millions of lab tests
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Arnold World April 2023
Photobiocatalytic Strategies for Organic Synthesis
Information storage across a microbial community using universal RNA memory
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BØPosphere – April 2023
Whole-genome sequences from wild-type and laboratory-evolved strains define the alleleome and establish its hallmarks
From observational to actionable: rethinking omics in biologics production
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Alonosphere April 2023
Damage dynamics and the role of chance in the timing of E. coli cell death
Exploring scenarios for the food system-zoonotic risk interface
Inflammation and bacteriophages affect DNA inversion states and functionality of the gut microbiota
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BØPosphere – March 2023
Multiomic signatures of body mass index identify heterogeneous health phenotypes and responses to a lifestyle intervention
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RabLab April 2023
Cachexia: A systemic consequence of progressive, unresolved disease
Maternal low-calorie sweetener consumption rewires hypothalamic melanocortin circuits via a gut microbial co-metabolite pathway
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Alonosphere March 2023
Competing constraints shape the nonequilibrium limits of cellular decision-making
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RabLab March 2023
Protein-metabolite interactomics of carbohydrate metabolism reveal regulation of lactate dehydrogenase
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Arnold World March 2023
Enzyme function prediction using contrastive learning
Genome mining unveils a class of ribosomal peptides with two amino termini
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RabLab February 2023
Thrifty energy metabolism in solid tumours
Complex regulation in a Comamonas platform for diverse aromatic carbon metabolism
The SLC25A47 locus controls gluconeogenesis and energy expenditure
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BØPosphere – February 2023
Proteome allocation is linked to transcriptional regulation through a modularized transcriptome
Laboratory evolution reveals general and specific tolerance mechanisms for commodity chemicals
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BØPosphere – January 2023
An Automated Scientist to Design and Optimize Microbial Strains for the Industrial Production of Small Molecules
Genome-scale metabolic reconstruction of 7,302 human microorganisms for personalized medicine
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RabLab January 2023
Immunoediting instructs tumor metabolic reprogramming to support immune evasion
Integrated multi-omics reveals anaplerotic rewiring in methylmalonyl-CoA mutase deficiency
Glycine homeostasis requires reverse SHMT flux
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Arnold World February 2023
Microbial sensor variation across biogeochemical conditions in the terrestrial deep subsurface
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Arnold World January 2023
Comparative study of two Saccharomyces cerevisiae strains with kinetic models at genome-scale
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Alonosphere – January 2023
Rules for body fat interventions based on an operating point mechanism
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