Arnold World April 2023

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Chemical reviews

Photobiocatalytic Strategies for Organic Synthesis.

2023-04-28

PubMed:37115521; DOI:10.1021/acs.chemrev.2c00767

Megan A Emmanuel¹, Sophie G Bender², Catherine Bilodeau², Jose M Carceller², Jacob S DeHovitz¹, Haigen Fu¹, Yi Liu¹, Bryce T Nicholls¹, Yao Ouyang², Claire G Page¹, Tianzhang Qiao², Felix C Raps², Damien R Sorigué², Shang-Zheng Sun², Joshua Turek-Herman¹, Yuxuan Ye², Ariadna Rivas-Souchet², Jingzhe Cao¹, Todd K Hyster²

Affiliations

Department of Chemistry, Princeton University, Princeton, New Jersey 08544, United States
Department of Chemistry and Chemical Biology, Cornell University, Ithaca, New York 14853, United States

Photobiocatalytic Strategies for Organic Synthesis by @HysterLab at @CornellChem in @ACSChemRev https://pubs.acs.org/doi/10.1021/acs.chemrev.2c00767…

2023-04-28

This is as awesome collaborative effort for the entire lab. Thank you @Megz_Ayana for being our fearless leader. Congrats to everyone!

2023-05-03

bioRxiv

Information storage across a microbial community using universal RNA memory

2023-04-16

DOI:10.1101/2023.04.16.536800

P. B. Kalvapalle, A. Staubus, M. J. Dysart, L. Gambill, K. Reyes Gamas, L. Chieh Lu, J. J. Silberg, L. B. Stadler, J. Chappell

Affiliations

Rice University

This preprint looks so cool: storing a record of bacteria:bacteria interactions by inserting information into ribosomal RNA – new work from @ChappellLab

2023-04-17

Check out our latest preprint on using synthetic RNA memory to record gene transfer across real microbial consortia. An amazing collaborative project at Rice U between @ChappellLab, @JoffSilberg, and @lauren_stadler labs!

2023-04-17

In microbial realms, complex and grand,
Biological recorders, they expand,
Using cat-RNA’s code,
In rRNA they stowed,
Info about gene transfers, a plan.

Amplicon sequencing, a tool so keen,
Revealed microbial secrets, unseen,
Conjugation’s dance, they spied,
With RNA-addressable memory wide,
In wastewater’s world, a vibrant scene.

RAM’s promise, a biosurveillance flight,
Microbiome’s mysteries brought to light,
Environmental reins, they hold,
Gene transfers, stories untold,
In RNA’s embrace, insights take flight.

human-physiology

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PLoS pathogens

The E2 glycoprotein holds key residues for Mayaro virus adaptation to the urban Aedes aegypti mosquito.

2023-04-05

PubMed:37018377; DOI:10.1371/journal.ppat.1010491

Chelsea Cereghino¹, Ferdinand Roesch², Lucía Carrau², Alexandra Hardy², Helder V Ribeiro-Filho³, Annabelle Henrion-Lacritick⁴, Cassandra Koh⁴, Jeffrey M Marano¹, Tyler A Bates¹, Pallavi Rai¹, Christina Chuong¹, Shamima Akter¹, Thomas Vallet², Hervé Blanc⁴, Truitt J Elliott⁵, Anne M Brown⁵, Pawel Michalak¹, Tanya LeRoith¹, Jesse D Bloom⁶, Rafael Elias Marques³, Maria-Carla Saleh⁴, Marco Vignuzzi², James Weger-Lucarelli¹

Affiliations

Department of Biomedical Sciences and Pathobiology, VA-MD Regional College of Veterinary Medicine, Virginia Tech, Blacksburg, Virginia, United States of America
Institut Pasteur, Viral Populations and Pathogenesis Unit, Centre National de la Recherche Scientifique UMR 3569, Paris, France
Brazilian Biosciences National Laboratory, Brazilian Center for Research in Energy and Materials (CNPEM), Campinas, São Paulo, Brazil
Institut Pasteur, Viruses and RNA Interference Unit, Centre National de la Recherche Scientifique UMR 3569, Paris, France
Program in Genetics, Bioinformatics, and Computational Biology (GBCB), Virginia Tech, Blacksburg, Virginia, United States of America
Basic Sciences Division and Computational Biology Program, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America

Here is a collaboration that @FerdinandRoesch undertook with @WegerJames to identify how Mayor virus could adapt and improve fitness in vivo:
#PLOSPathogens: The E2 glycoprotein holds key residues for Mayaro virus adaptation to the urban Aedes aegypti …

2023-04-18

synbio-meteng

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ACS synthetic biology

Imaging Method Using CRISPR/dCas9 and Engineered gRNA Scaffolds Can Perturb Replication Timing at the HSPA1 Locus.

2023-04-14

PubMed:37058298; DOI:10.1021/acssynbio.2c00433

Xiong Xiong¹, Ipek Tasan², Che Yang², Meng Zhang¹, Gabriela A Hernandez Gonzalez³, Shuting Liu³, Pankaj Chaturvedi³, Andrew S Belmont³, Huimin Zhao¹

Affiliations

Department of Chemical and Biomolecular Engineering, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States
Department of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States
Department of Cell and Developmental Biology, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States

bioRxiv

An end-to-end pipeline for succinic acid production at an industrially relevant scale using Issatchenkia orientalis

2023-04-30

DOI:10.1101/2023.04.30.538856

V. G. Tran, S. Mishra, S. S. Bhagwat, S. Shafaei, Y. Shen, J. L. Allen, B. A. Crosly, S.-I. Tan, Z. Fatma, J. Rabinowitz, J. S. Guest, V. Singh, H. Zhao

Affiliations

evolutionary-engineering–proteins

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Angewandte Chemie (International ed. in English)

Ene Reductase Enabled Intramolecular β-C-H Functionalization of Substituted Cyclohexanones for Efficient Synthesis of Bridged Bicyclic Nitrogen Scaffolds.

2023-04-01

PubMed:37002909; DOI:10.1002/anie.202302125

Guangde Jiang¹, Chunshuai Huang², Wesley Harrison¹, Hongxiang Li², Megan Zhou², Huimin Zhao¹

Affiliations

Department of Chemical and Biomolecular Engineering, Center for Advanced Bioenergy and Bioproducts Innovation, Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA
Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA

Ene Reductase Enabled Intramolecular beta-C-H Functionalization of Substituted Cyclohexanones for Efficient Synthesis of Bridged Bicyclic Nitrogen Scaffolds (Huimin Zhao and co-workers) @HuiminZhaoLab @ChBEIllinois https://onlinelibrary.wiley.com/doi/10.1002/anie.202302125…

2023-04-26

Dalton transactions (Cambridge, England : 2003)

Iridium(III) polypyridine artificial metalloenzymes with tunable photophysical properties: a new platform for visible light photocatalysis in aqueous solution.

2023-04-15

PubMed:37060130; DOI:10.1039/d3dt00932g

Bingqing Liu¹, Yasmine S Zubi¹, Jared C Lewis¹

Affiliations

Department of Chemistry, Indiana University, Bloomington, Indiana 47405, USA.

This study shows that we can incorporate Ir(III) photocatalysts into POP to do EnT catalysis. Lots of details on scaffold/cofactor/substrate interactions in this one, including the first hints of enantioselectivity.

2023-04-26

evolution-physiology

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bioRxiv

Association between SARS-CoV-2 and metagenomic content of samples from the Huanan Seafood Market

2023-04-26

DOI:10.1101/2023.04.25.538336

J. D. Bloom

Affiliations

Fred Hutchinson Cancer Research Center

kedalionlabs.com

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