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RabLab – June 2023

Quantitative analysis of metabolic fluxes in brown fat and skeletal muscle during thermogenesis

Liver and muscle circadian clocks cooperate to support glucose tolerance in mice

Adolescent exposure to low-dose THC disrupts energy balance and adipose organ homeostasis in adulthood

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Arnold World June 2023

Mechanism and Dynamics of Photodecarboxylation Catalyzed by Lactate Monooxygenase

Reversing the Enantioselectivity of Enzymatic Carbene N-H Insertion Through Mechanism-Guided Protein Engineering

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Alonosphere June 2023

The global human day

Autotrophic growth of E. coli is achieved by a small number of genetic changes

Single-cell biology: what does the future hold?

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BØPosphere – June 2023

Systems biology of competency in Vibrio natriegens is revealed by applying novel data analytics to the transcriptome

Literate programming for iterative design-build-test-learn cycles in bioengineering

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RabLab May 2023

Impact of acute stress on murine metabolomics and metabolic flux

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Arnold World May 2023

Self-driving laboratories to autonomously navigate the protein fitness landscape

DeCOIL: Optimization of Degenerate Codon Libraries for Machine Learning-Assisted Protein Engineering

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BØPosphere – May 2023

Metabolic homeostasis and growth in abiotic cells

Complete integration of carbene-transfer chemistry into biosynthesis

StressME: unified computing framework of Escherichia coli metabolism, gene expression, and stress responses

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Alonosphere May 2023

Pregnancy and postpartum dynamics revealed by an atlas of millions of lab tests

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Arnold World April 2023

Photobiocatalytic Strategies for Organic Synthesis

Information storage across a microbial community using universal RNA memory

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BØPosphere – April 2023

Whole-genome sequences from wild-type and laboratory-evolved strains define the alleleome and establish its hallmarks

From observational to actionable: rethinking omics in biologics production

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Alonosphere April 2023

Damage dynamics and the role of chance in the timing of E. coli cell death

Exploring scenarios for the food system-zoonotic risk interface

Inflammation and bacteriophages affect DNA inversion states and functionality of the gut microbiota

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BØPosphere – March 2023

Multiomic signatures of body mass index identify heterogeneous health phenotypes and responses to a lifestyle intervention

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RabLab April 2023

Cachexia: A systemic consequence of progressive, unresolved disease

Maternal low-calorie sweetener consumption rewires hypothalamic melanocortin circuits via a gut microbial co-metabolite pathway

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Alonosphere March 2023

Competing constraints shape the nonequilibrium limits of cellular decision-making

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Alonosphere February 2023

The global biomass of wild mammals

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RabLab March 2023

Protein-metabolite interactomics of carbohydrate metabolism reveal regulation of lactate dehydrogenase

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Arnold World March 2023

Enzyme function prediction using contrastive learning

Genome mining unveils a class of ribosomal peptides with two amino termini

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RabLab February 2023

Thrifty energy metabolism in solid tumours

Complex regulation in a Comamonas platform for diverse aromatic carbon metabolism

The SLC25A47 locus controls gluconeogenesis and energy expenditure

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BØPosphere – February 2023

Proteome allocation is linked to transcriptional regulation through a modularized transcriptome

Laboratory evolution reveals general and specific tolerance mechanisms for commodity chemicals

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BØPosphere – January 2023

An Automated Scientist to Design and Optimize Microbial Strains for the Industrial Production of Small Molecules

Genome-scale metabolic reconstruction of 7,302 human microorganisms for personalized medicine

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RabLab January 2023

Immunoediting instructs tumor metabolic reprogramming to support immune evasion

Integrated multi-omics reveals anaplerotic rewiring in methylmalonyl-CoA mutase deficiency

Glycine homeostasis requires reverse SHMT flux

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Arnold World February 2023

Microbial sensor variation across biogeochemical conditions in the terrestrial deep subsurface

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Arnold World January 2023

Comparative study of two Saccharomyces cerevisiae strains with kinetic models at genome-scale

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Alonosphere – January 2023

Rules for body fat interventions based on an operating point mechanism

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