Academic lineage
An automated workflow for multi-omics screening of microbial model organisms
- Stefano Donati, Matthias Mattanovich, Pernille Hjort, …, Tadas JakoÄiĆ«nas, Lars Keld Nielsen, Douglas McCloskey
- NPJ Syst Biol Appl, 10.1038/s41540-023-00277-6
Automating the design-build-test-learn cycle towards next-generation bacterial cell factories
- NicolĂĄs Gurdo, Daniel C Volke, Douglas McCloskey, …, Daniel C Volke, Douglas McCloskey, Pablo IvĂĄn Nikel
- N Biotechnol, 10.1016/j.nbt.2023.01.002
Precision diagnostic approach to predict 5-year risk for microvascular complications in type 1 diabetes
- Naba Al-Sari, Svetlana Kutuzova, Tommi Suvitaival, …, Peter Rossing, Douglas McCloskey, Cristina Legido-Quigley
- EBioMedicine, 10.1016/j.ebiom.2022.104032
A Comprehensive Evaluation of Metabolomics Data Preprocessing Methods for Deep Learning
- Krzysztof Jan Abram, Douglas McCloskey
- None, 10.3390/metabo12030202
Corrigendum: Multi-Omics Analysis of Fatty Alcohol Production in Engineered Yeasts Saccharomyces cerevisiae and Yarrowia lipolytica
- Jonathan Dahlin, Carina Holkenbrink, Eko Roy Marella, …, Markus J HerrgĂ„rd, Lars Mathias Blank, Irina Borodina
- None, 10.3389/fgene.2020.637738
SmartPeak Automates Targeted and Quantitative Metabolomics Data Processing
- Svetlana Kutuzova, Pasquale Colaianni, Hannes Röst, …, Lars Nielsen, Markus J HerrgĂ„rd, Douglas McCloskey
- Anal Chem, 10.1021/acs.analchem.0c03421
High-Resolution Scanning of Optimal Biosensor Reporter Promoters in Yeast
- Francesca Ambri, Vasil D’Ambrosio, Roberto Di Blasi, …, Douglas McCloskey, Michael K Jensen, Jay D Keasling
- ACS Synth Biol, 10.1021/acssynbio.9b00333
Laboratory evolution reveals a two-dimensional rate-yield tradeoff in microbial metabolism
- Chuankai Cheng, Edward J O’Brien, Douglas McCloskey, …, Adam M Feist, Bernhard O Palsson, Zachary A King
- PLoS Comput Biol, 10.1371/journal.pcbi.1007066
A White-Box Machine Learning Approach for Revealing Antibiotic Mechanisms of Action
- Jason H Yang, Sarah N Wright, Meagan Hamblin, …, Bernhard O Palsson, Graham C Walker, James J Collins
- Cell, 10.1016/j.cell.2019.04.016
Growth Adaptation of gnd and sdhCB Escherichia coli Deletion Strains Diverges From a Similar Initial Perturbation of the Transcriptome
- Douglas McCloskey, Sibei Xu, Troy E Sandberg, …, Richard Szubin, Adam M Feist, Bernhard O Palsson
- None, 10.3389/fmicb.2018.01793
Multiple Optimal Phenotypes Overcome Redox and Glycolytic Intermediate Metabolite Imbalances in Escherichia coli pgi Knockout Evolutions
- Douglas McCloskey, Sibei Xu, Troy E Sandberg, …, Richard Szubin, Adam M Feist, Bernhard O Palsson
- Appl Environ Microbiol, 10.1128/aem.00823-18
Adaptive laboratory evolution resolves energy depletion to maintain high aromatic metabolite phenotypes in Escherichia coli strains lacking the Phosphotransferase System
- Douglas McCloskey, Sibei Xu, Troy E Sandberg, …, Richard Szubin, Adam M Feist, Bernhard O Palsson
- Metab Eng, 10.1016/j.ymben.2018.06.005