Channel: Heme bioengineering

The bioengineering of processes to produce heme (American English), or haem (Commonwealth English. Heme is a precursor to hemoglobin, which is necessary to bind oxygen in the bloodstream. Wikipedia (CC BY-SA 3.0)

    2023 Articles

    286 articles

    Engineering Escherichia coli for efficient assembly of heme proteins

    Comment Section

    Heme acquisition and tolerance in Gram-positive model bacteria: An orchestrated balance

    Comment Section

    Microbial Synthesis of Heme b: Biosynthetic Pathways, Current Strategies, Detection, and Future Prospects

    Comment Section

    Applications of the Whole-Cell System in the Efficient Biosynthesis of Heme

    • Hongfei Su, Xiaolin Chen, Shijing Chen, …, Shijing Chen, Mingzhang Guo, Huilin Liu
    • Int J Mol Sci, 10.3390/ijms24098384
    Comment Section

    Evidence for Porphyrin-Mediated Electron Transfer in the Radical SAM Enzyme HutW

    • Marley Brimberry, Patrick Corrigan, Alexey Silakov, …, Patrick Corrigan, Alexey Silakov, William N Lanzilotta
    • Biochemistry, 10.1021/acs.biochem.2c00474
    Comment Section

    NosP Detection of Heme Modulates Burkholderia thailandensis Biofilm Formation

    • Jiayuan Fu, Lisa-Marie Nisbett, Yulong Guo, …, Lisa-Marie Nisbett, Yulong Guo, Elizabeth M Boon
    • Biochemistry, 10.1021/acs.biochem.3c00187
    Comment Section

    In Campylobacter jejuni, a new type of chaperone receives heme from ferrochelatase

    • Jordi Zamarreño Beas, Marco A M Videira, Val Karavaeva, …, Mafalda R Almeida, Filipa Sousa, Lígia M Saraiva
    • None, 10.3389/fgene.2023.1199357
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    Sustainable and high-level microbial production of plant hemoglobin in Corynebacterium glutamicum

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    Notes from the Underground: Heme Homeostasis in C. elegans

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    Bioproduction of porphyrins, phycobilins, and their proteins using microbial cell factories: engineering, metabolic regulations, challenges, and perspectives

    • Young Jin Ko, Myeong-Eun Lee, Byeong-Hyeon Cho, …, Jeong Eun Hyeon, Joo Hee Han, Sung Ok Han
    • Crit Rev Biotechnol, 10.1080/07388551.2023.2168512
    Comment Section

    2022 Articles

    29 articles

    Systematic engineering of Saccharomyces cerevisiae for efficient synthesis of hemoglobins and myoglobins

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    Efficient De Novo Biosynthesis of Heme by Membrane Engineering in Escherichia coli

    • Zhexian Geng, Jinxia Ge, Wei Cui, …, Hui Zhou, Jieying Deng, Baocai Xu
    • Int J Mol Sci, 10.3390/ijms232415524
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    Whole-Cell P450 Biocatalysis Using Engineered Escherichia coli with Fine-Tuned Heme Biosynthesis

    • Baodong Hu, Haibo Yu, Jingwen Zhou, …, Guocheng Du, Sang Yup Lee, Xinrui Zhao
    • Adv Sci (Weinh), 10.1002/advs.202205580
    Comment Section

    Ordered Motions in the Nitric-Oxide Dioxygenase Mechanism of Flavohemoglobin and Assorted Globins with Tightly Coupled Reductases

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    Genomic organization and gene evolution of two warm temperature acclimation proteins (Wap65s) of Micropterus salmoides and their responses to temperature and bacterial/viral infections

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    Circulating hemopexin modulates anthracycline cardiac toxicity in patients and in mice

    • Jing Liu, Sarah Lane, Rahul Lall, …, Alessandra Ghigo, Robert E Gerszten, Aarti Asnani
    • Sci Adv, 10.1126/sciadv.adc9245
    Comment Section

    Pseudomonas aeruginosa and its multiple strategies to access iron

    • Isabelle J Schalk, Quentin Perraud, Isabelle J Schalk, …, Quentin Perraud, Isabelle J Schalk, Quentin Perraud
    • Environ Microbiol, 10.1111/1462-2920.16328
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    New Insights Regarding Hemin Inhibition of the Purified Rat Brain 2-Oxoglutarate Carrier and Relationships with Mitochondrial Dysfunction

    • Daniela Valeria Miniero, Nicola Gambacorta, Anna Spagnoletta, …, Orazio Nicolotti, Ciro Leonardo Pierri, Annalisa De Palma
    • None, 10.3390/jcm11247519
    Comment Section

    BACH1 regulates erythrophagocytosis and iron-recycling in β-thalassemia

    • Tipparat Penglong, Apisara Saensuwanna, Nuttanan Pholngam, …, Natta Tansila, Hansuk Buncherd, Kanitta Srinoun
    • Genes Cells, 10.1111/gtc.13004
    Comment Section

    Evolution and molecular basis of a novel allosteric property of crocodilian hemoglobin

    • Chandrasekhar Natarajan, Anthony V Signore, Naim M Bautista, …, Jeremy R H Tame, Angela Fago, Jay F Storz
    • Curr Biol, 10.1016/j.cub.2022.11.049
    Comment Section