Precision fermentation is an approach to manufacturing specific functional products which intends to minimise the production of unwanted by-products through the application of synthetic biology, particularly by generating synthetic "cell factories" with engineered genomes and metabolic pathways optimised to produce the desired compounds as efficiently as possible with the available resources. Precision fermentation of genetically modified microorganisms may be used to manufacture proteins needed for cell culture media, providing for serum-free cell culture media in the manufacturing process of cultured meat. Wikipedia (CC BY-SA 3.0)
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2023 Articles
707 articles
Full-length versus truncated α-factor secretory signal sequences for expression of recombinant human insulin precursor in yeast Pichia pastoris: a comparison
- Dini Nurdiani, Hariyatun Hariyatun, Eko Wahyu Putro, …, Eko Wahyu Putro, Fadillah Putri Patria, Wien Kusharyoto
- None, 10.1186/s43141-023-00521-w
One-pot biosynthesis of N-acetylneuraminic acid from chitin via combination of chitin-degrading enzymes, N-acetylglucosamine-2-epimerase, and N-neuraminic acid aldolase
- Quanzhen Liu, Guoguang Wei, Pengfan Yang, …, Kequan Chen, Pingkai Ouyang, Alei Zhang
- None, 10.3389/fmicb.2023.1156924
Robust nano-enzyme conjugates for the sustainable synthesis of a rare sugar D-tagatose
- Shushil Kumar Rai, Aishwarya Singh, Baljinder Singh Kauldhar, …, Aishwarya Singh, Baljinder Singh Kauldhar, Sudesh Kumar Yadav
- Int J Biol Macromol, 10.1016/j.ijbiomac.2023.123406
Improving solubility and copy number of taxadiene synthase to enhance the titer of taxadiene in Yarrowia lipolytica
- Man Xu, Wenliang Xie, Zhen Luo, Chun-Xiu Li, Qiang Hua, Jianhe Xu
- None, 10.1016/j.synbio.2023.04.002
Enhancing the Hydrolysis and Acyl Transfer Activity of Carboxylesterase DLFae4 by a Combinational Mutagenesis and In-Silico Method
- Longxiang Li, Liping Ding, Yuting Shao, …, Guojun Wu, Zhe Song, Zhihong Xin
- None, 10.3390/foods12061169
Characterization of a novel bifunctional enzyme from buffalo rumen metagenome and its effect on in vitro ruminal fermentation and microbial community composition
- Zhenxiang Meng, Jing Ma, Zhanying Sun, …, Jing Leng, Weiyun Zhu, Yanfen Cheng
- None, 10.1016/j.aninu.2023.01.004
Thermostability enhancement of Escherichia coli phytase by error-prone polymerase chain reaction (epPCR) and site-directed mutagenesis
- Hongguan Xing, Pingping Wang, Xing Yan, …, Xinliang Li, Rui Liu, Zhihua Zhou
- None, 10.3389/fbioe.2023.1167530
Metabolic Engineering of De Novo Pathway for the Production of 2′-Fucosyllactose in Escherichia coli
- Chenchen Li, Mengli Li, Miaomiao Hu, …, Mengli Li, Miaomiao Hu, Tao Zhang
- Mol Biotechnol, 10.1007/s12033-023-00657-7
Improving the Activity and Stability of Serine Protease ThAPT3 by Alleviating Self-Cleavage and Its Application in Deproteinization of Shrimp Shells
- Xiao Wang, Tao Dong, Qiao Zhou, …, Bin Yao, Huoqing Huang, Huiying Luo
- J Agric Food Chem, 10.1021/acs.jafc.3c01618
Thermotolerant and protease-resistant GH5 family β-mannanase with CBM1 from Penicillium aculeatum APS1: purification and characterization
- Purvi Bangoria, Amisha Patel, Amita R Shah, …, Purvi Bangoria, Amisha Patel, Amita R Shah
- None, 10.1007/s13205-023-03529-8
2022 Articles
69 articles
Precision cellular agriculture: The future role of recombinantly expressed protein as food
- John H Dupuis, Lennie K Y Cheung, Lenore Newman, …, Lenore Newman, Derek R Dee, Rickey Y Yada
- Compr Rev Food Sci Food Saf, 10.1111/1541-4337.13094
Generation of an anti-idiotypic affibody-based masking domain for conditional activation of EGFR-targeting
- Anna Mestre Borras, Charles Dahlsson Leitao, Stefan Ståhl, …, Charles Dahlsson Leitao, Stefan Ståhl, John Löfblom
- N Biotechnol, 10.1016/j.nbt.2022.12.002
Engineering Methyltransferase and Sulfoxide Synthase for High-Yield Production of Ergothioneine
- Luwen Zhang, Jiawei Tang, Meiqing Feng, …, Jiawei Tang, Meiqing Feng, Shaoxin Chen
- J Agric Food Chem, 10.1021/acs.jafc.2c07859
Identification of genetic variants of the industrial yeast Komagataella phaffii (Pichia pastoris) that contribute to increased yields of secreted heterologous proteins
- Benjamin Offei, Stephanie Braun-Galleani, Anjan Venkatesh, …, Kevin E O’Connor, Kevin P Byrne, Kenneth H Wolfe
- PLoS Biol, 10.1371/journal.pbio.3001877
Systems metabolic engineering upgrades Corynebacterium glutamicum to high-efficiency cis, cis-muconic acid production from lignin-based aromatics
- Fabia Weiland, Nadja Barton, Michael Kohlstedt, …, Michael Kohlstedt, Judith Becker, Christoph Wittmann
- Metab Eng, 10.1016/j.ymben.2022.12.005
Functional production of clostridial circularin A in Lactococcus lactis NZ9000 and mutational analysis of its aromatic and cationic residues
- Fangfang Liu, Auke J van Heel, Jingqi Chen, …, Auke J van Heel, Jingqi Chen, Oscar P Kuipers
- None, 10.3389/fmicb.2022.1026290
Metabolic engineering of Corynebacterium glutamicum for l-tyrosine production from glucose and xylose
- Eldin Kurpejović, Arthur Burgardt, Gülsüm Merve Bastem, …, Nora Junker, Volker F Wendisch, Berna Sariyar Akbulut
- J Biotechnol, 10.1016/j.jbiotec.2022.12.005
Engineering the Thermostability of a d-Carbamoylase Based on Ancestral Sequence Reconstruction for the Efficient Synthesis of d-Tryptophan
- Jiamin Hu, Xiaoyu Chen, Lu Zhang, …, Jieyu Zhou, Guochao Xu, Ye Ni
- J Agric Food Chem, 10.1021/acs.jafc.2c07781
Functional verification and characterization of a type-III geranylgeranyl diphosphate synthase gene from Sporobolomyces pararoseus NGR
- Jianyu Yan, Chunji Li, Ning Zhang, …, Chunwang Li, Yunjiao Wang, Bingxue Li
- None, 10.3389/fmicb.2022.1032234
Carrier-Free Immobilization of Multi-Enzyme Complex Facilitates Inu2005Vitro Synthetic Enzymatic Biosystem for Biomanufacturing
- Miaomiao Liu, Yuhong Song, Yi-Heng P Job Zhang, …, Yunhong Song, Yi-Heng P Job Zhang, Chun You
- ChemSusChem, 10.1002/cssc.202202153