Biosynthesis of inorganic nanomaterials using microbial cells and bacteriophages
- Yoojin Choi, Sang Yup Lee
- Nat Rev Chem, 10.1038/s41570-020-00221-w
Adapting educational experiences for the chemists of tomorrow
- Mik Fanguy, David G Churchill, Mik Fanguy, …, Mik Fanguy, Sang Yup Lee, David G Churchill
- Nat Rev Chem, 10.1038/s41570-021-00258-5
Targeted and high-throughput gene knockdown in diverse bacteria using synthetic sRNAs
- Jae Sung Cho, Dongsoo Yang, Cindy Pricilia Surya Prabowo, …, Jae Yong Ryu, Hyun Uk Kim, Sang Yup Lee
- Nat Commun, 10.1038/s41467-023-38119-y
Biohybrid CO 2 electrolysis for the direct synthesis of polyesters from CO 2
- Jinkyu Lim, So Young Choi, Jae Won Lee, …, Jae Won Lee, Sang Yup Lee, Hyunjoo Lee
- Proc Natl Acad Sci U S A, 10.1073/pnas.2221438120
Production of 3-Hydroxypropionic Acid from Renewable Substrates by Metabolically Engineered Microorganisms: A Review
- Xiaodi Wang, Zhenzhen Cui, Xi Sun, …, Xi Sun, Zhiwen Wang, Tao Chen
- Molecules, 10.3390/molecules28041888
Metabolic engineering of Escherichia coli for the production of an antifouling agent zosteric acid
- Peichao Zhang, Jing Gao, Haiyang Zhang, …, Zhen Liu, Sang Yup Lee, Xiangzhao Mao
- Metab Eng, 10.1016/j.ymben.2023.02.007
Improved terephthalic acid production from p-xylene using metabolically engineered Pseudomonas putida
- Zi Wei Luo, Kyeong Rok Choi, Sang Yup Lee, …, Zi Wei Luo, Kyeong Rok Choi, Sang Yup Lee
- Metab Eng, 10.1016/j.ymben.2023.01.007
Can microbes be harnessed to reduce atmospheric loads of greenhouse gases?
- Yeah-Ji Ahn, Jong An Lee, Kyeong Rok Choi, …, Kyeong Rok Choi, Junho Bang, Sang Yup Lee
- Environ Microbiol, 10.1111/1462-2920.16161
Metabolic engineering for sustainability and health
- Gi Bae Kim, So Young Choi, In Jin Cho, …, In Jin Cho, Da-Hee Ahn, Sang Yup Lee
- Trends Biotechnol, 10.1016/j.tibtech.2022.12.014
Whole-Cell P450 Biocatalysis Using Engineered Escherichia coli with Fine-Tuned Heme Biosynthesis
- Baodong Hu, Haibo Yu, Jingwen Zhou, …, Guocheng Du, Sang Yup Lee, Xinrui Zhao
- Adv Sci (Weinh), 10.1002/advs.202205580
Factors affecting the competitiveness of bacterial fermentation
- Jong An Lee, Hyun Uk Kim, Jeong-Geol Na, …, Yoo-Sung Ko, Jae Sung Cho, Sang Yup Lee
- Trends Biotechnol, 10.1016/j.tibtech.2022.10.005
Metabolic engineering of Mannheimia succiniciproducens for malic acid production using dimethylsulfoxide as an electron acceptor
- Jong An Lee, Jung Ho Ahn, Gi Bae Kim, …, Sol Choi, Ji Yeon Kim, Sang Yup Lee
- Biotechnol Bioeng, 10.1002/bit.28242
An interactive metabolic map of bio-based chemicals
- Woo Dae Jang, Gi Bae Kim, Sang Yup Lee, …, Woo Dae Jang, Gi Bae Kim, Sang Yup Lee
- Trends Biotechnol, 10.1016/j.tibtech.2022.07.013
Systematic strategies for developing phage resistant Escherichia coli strains
- Xuan Zou, Xiaohong Xiao, Ziran Mo, …, Shi Chen, Lianrong Wang, Sang Yup Lee
- Nat Commun, 10.1038/s41467-022-31934-9
Metabolic and cellular engineering for the production of natural products
- Dongsoo Yang, Hyunmin Eun, Cindy Pricilia Surya Prabowo, Sumin Cho, Sang Yup Lee
- Curr Opin Biotechnol, 10.1016/j.copbio.2022.102760
Improved production of heme using metabolically engineered Escherichia coli
- Kyeong Rok Choi, Hye Eun Yu, Hoseong Lee, Sang Yup Lee
- Biotechnol Bioeng, 10.1002/bit.28194
Production of zinc protoporphyrin IX by metabolically engineered Escherichia coli
- Kyeong Rok Choi, Hye Eun Yu, Sang Yup Lee
- Biotechnol Bioeng, 10.1002/bit.28195
Light-Driven Ammonia Production by Azotobacter vinelandii Cultured in Medium Containing Colloidal Quantum Dots
- Sungjun Koh, Yoojin Choi, Ilsong Lee, …, Young-Shin Park, Sang Yup Lee, Doh C Lee
- J Am Chem Soc, 10.1021/jacs.2c01886
Optogenetic tools for microbial synthetic biology
- Natalie Chia, Sang Yup Lee, Yaojun Tong
- Biotechnol Adv, 10.1016/j.biotechadv.2022.107953
An operator-based expression toolkit for Bacillus subtilis enables fine-tuning of gene expression and biosynthetic pathway regulation
- Gang Fu, Jie Yue, Dandan Li, Yixin Li, Sang Yup Lee, Dawei Zhang
- Proc Natl Acad Sci U S A, 10.1073/pnas.2119980119
Secretory production of spider silk proteins in metabolically engineered Corynebacterium glutamicum for spinning into tough fibers
- Qing Jin, Fang Pan, Chun-Fei Hu, Sang Yup Lee, Xiao-Xia Xia, Zhi-Gang Qian
- Metab Eng, 10.1016/j.ymben.2022.01.009
Biosynthesis and applications of iron oxide nanocomposites synthesized by recombinant Escherichia coli
- Jae Hwan Jung, Minkyung Cho, Tae Seok Seo, Sang Yup Lee
- Appl Microbiol Biotechnol, 10.1007/s00253-022-11779-4
Production of phenylpropanoids and flavonolignans from glycerol by metabolically engineered Escherichia coli
- Seon Young Park, Dongsoo Yang, Shin Hee Ha, Sang Yup Lee
- Biotechnol Bioeng, 10.1002/bit.28008
Clostridium acetobutylicum atp G-Knockdown Mutants Increase Extracellular pH in Batch Cultures
- Yu-Sin Jang, Hyeon Jeong Seong, Seong Woo Kwon, …, Haeng Lim Lee, Ye Rin Yoon, Sang Yup Lee
- None, 10.3389/fbioe.2021.754250
Characterization and engineering of Streptomyces griseofuscus DSM 40191 as a potential host for heterologous expression of biosynthetic gene clusters
- Tetiana Gren, Christopher M Whitford, Omkar S Mohite, …, Julie B Nielsen, Sang Yup Lee, Tilmann Weber
- Sci Rep, 10.1038/s41598-021-97571-2
A versatile genetic engineering toolkit for E. coli based on CRISPR-prime editing
- Yaojun Tong, Tue S Jørgensen, Christopher M Whitford, Tilmann Weber, Sang Yup Lee
- Nat Commun, 10.1038/s41467-021-25541-3
Microbial food: microorganisms repurposed for our food
- Kyeong Rok Choi, Hye Eun Yu, Sang Yup Lee
- Microb Biotechnol, 10.1111/1751-7915.13911
Applications of artificial intelligence to enzyme and pathway design for metabolic engineering
- Woo Dae Jang, Gi Bae Kim, Yeji Kim, Sang Yup Lee
- Curr Opin Biotechnol, 10.1016/j.copbio.2021.07.024
Physiological effects, biosynthesis, and derivatization of key human milk tetrasaccharides, lacto- N -tetraose, and lacto- N -neotetraose
- Yingying Zhu, Guocong Luo, Li Wan, Jiawei Meng, Sang Yup Lee, Wanmeng Mu
- Crit Rev Biotechnol, 10.1080/07388551.2021.1944973
In Situ Biosynthesis of a Metal Nanoparticle Encapsulated in Alginate Gel for Imageable Drug-Delivery System
- Moon Il Kim, Chan Yeong Park, Ji Min Seo, …, Jong Pil Park, Hyun Gyu Park, Tae Jung Park
- ACS Appl Mater Interfaces, 10.1021/acsami.1c02286
Three-dimensional label-free visualization and quantification of polyhydroxyalkanoates in individual bacterial cell in its native state
- So Young Choi, Jeonghun Oh, JaeHwang Jung, YongKeun Park, Sang Yup Lee
- Proc Natl Acad Sci U S A, 10.1073/pnas.2103956118
Drugs repurposed for COVID-19 by virtual screening of 6,218 drugs and cell-based assay
- Woo Dae Jang, Sangeun Jeon, Seungtaek Kim, Sang Yup Lee
- Proc Natl Acad Sci U S A, 10.1073/pnas.2024302118
Synthetic Formatotrophs for One-Carbon Biorefinery
- Junho Bang, Jung Ho Ahn, Jong An Lee, …, Gi Bae Kim, Jinwon Lee, Sang Yup Lee
- Adv Sci (Weinh), 10.1002/advs.202100199
Production of Rainbow Colorants by Metabolically Engineered Escherichia coli
- Dongsoo Yang, Seon Young Park, Sang Yup Lee
- Adv Sci (Weinh), 10.1002/advs.202100743
Escherichia coli as a platform microbial host for systems metabolic engineering
- Dongsoo Yang, Cindy Pricilia Surya Prabowo, Hyunmin Eun, …, In Jin Cho, Song Jiao, Sang Yup Lee
- Essays Biochem, 10.1042/ebc20200172
Production of Carminic Acid by Metabolically Engineered Escherichia coli
- Dongsoo Yang, Woo Dae Jang, Sang Yup Lee
- J Am Chem Soc, 10.1021/jacs.0c12406
Microbial production of multiple short-chain primary amines via retrobiosynthesis
- Dong In Kim, Tong Un Chae, Hyun Uk Kim, Woo Dae Jang, Sang Yup Lee
- Nat Commun, 10.1038/s41467-020-20423-6
A deep learning approach to evaluate the feasibility of enzymatic reactions generated by retrobiosynthesis
- Yeji Kim, Jae Yong Ryu, Hyun Uk Kim, Woo Dae Jang, Sang Yup Lee
- Biotechnol J, 10.1002/biot.202000605
DeepTFactor: A deep learning-based tool for the prediction of transcription factors
- Gi Bae Kim, Ye Gao, Bernhard O Palsson, Sang Yup Lee
- Proc Natl Acad Sci U S A, 10.1073/pnas.2021171118
Tunable Gene Expression System Independent of Downstream Coding Sequence
- Seung Min Yoo, Seung-Woon Jung, Jinho Yeom, Sang Yup Lee, Dokyun Na
- ACS Synth Biol, 10.1021/acssynbio.0c00029
Heat-responsive and time-resolved transcriptome and metabolome analyses of Escherichia coli uncover thermo-tolerant mechanisms
- Sinyeon Kim, Youngshin Kim, Dong Ho Suh, …, Seung Min Yoo, Sang Yup Lee, Sung Ho Yoon
- Sci Rep, 10.1038/s41598-020-74606-8
Escherichia coli is engineered to grow on CO 2 and formic acid
- Junho Bang, Chang Hun Hwang, Jung Ho Ahn, Jong An Lee, Sang Yup Lee
- Nat Microbiol, 10.1038/s41564-020-00793-9
Tools and strategies of systems metabolic engineering for the development of microbial cell factories for chemical production
- Yoo-Sung Ko, Je Woong Kim, Jong An Lee, …, Gi Bae Kim, Jeong Eum Park, Sang Yup Lee
- Chem Soc Rev, 10.1039/d0cs00155d
Microbial production of 4-amino-1-butanol, a four-carbon amino alcohol
- Cindy Pricilia Surya Prabowo, Jae Ho Shin, Jae Sung Cho, Tong Un Chae, Sang Yup Lee
- Biotechnol Bioeng, 10.1002/bit.27438
Enhanced succinic acid production by Mannheimia employing optimal malate dehydrogenase
- Jung Ho Ahn, Hogyun Seo, Woojin Park, …, Gi Bae Kim, Kyung-Jin Kim, Sang Yup Lee
- Nat Commun, 10.1038/s41467-020-15839-z
Modeling regulatory networks using machine learning for systems metabolic engineering
- Mun Su Kwon, Byung Tae Lee, Sang Yup Lee, Hyun Uk Kim
- Curr Opin Biotechnol, 10.1016/j.copbio.2020.02.014
Metabolic engineering strategies toward production of biofuels
- Kyeong Rok Choi, Song Jiao, Sang Yup Lee
- Curr Opin Chem Biol, 10.1016/j.cbpa.2020.02.009