Academic lineage
Central nervous system involvement in childhood acute lymphoblastic leukemia is linked to upregulation of cholesterol biosynthetic pathways
- A Cousins, O Olivares, E Markert, …, G Te Kronnie, E Gottlieb, C Halsey
- Leukemia, 10.1038/s41375-022-01722-x
Cancer-associated fibroblasts require proline synthesis by PYCR1 for the deposition of pro-tumorigenic extracellular matrix
- Emily J Kay, Karla Paterson, Carla Riera-Domingo, …, Karen Blyth, Michele Zagnoni, Sara Zanivan
- Nat Metab, 10.1038/s42255-022-00582-0
Metabolic adaptation of acute lymphoblastic leukemia to the central nervous system microenvironment is dependent on Stearoyl CoA desaturase
- Angela Maria Savino, Sara Isabel Fernandes, Orianne Olivares, …, Eyal Gottlieb, Shai Izraeli, Christina Halsey
- Nat Cancer, 10.1038/s43018-020-00115-2
2,4-dienoyl-CoA reductase regulates lipid homeostasis in treatment-resistant prostate cancer
- Arnaud Blomme, Catriona A Ford, Ernest Mui, …, Sarah-Maria Fendt, Sara Zanivan, Hing Y Leung
- Nat Commun, 10.1038/s41467-020-16126-7
Macropinocytosis Renders a Subset of Pancreatic Tumor Cells Resistant to mTOR Inhibition
- Evdokia Michalopoulou, Francesca R Auciello, Vinay Bulusu, …, Jennifer P Morton, Owen J Sansom, Jurre J Kamphorst
- Cell Rep, 10.1016/j.celrep.2020.01.080
Lactate Buildup at the Site of Chronic Inflammation Promotes Disease by Inducing CD4 + T Cell Metabolic Rewiring
- Valentina Pucino, Michelangelo Certo, Vinay Bulusu, …, Michele Bombardieri, Costantino Pitzalis, Claudio Mauro
- Cell Metab, 10.1016/j.cmet.2019.10.004