Synthetic fuels: what are they and where do they come from?
- John C Ruth, Gregory Stephanopoulos, John C Ruth, …, Gregory Stephanopoulos, John C Ruth, Gregory Stephanopoulos
- Curr Opin Biotechnol, 10.1016/j.copbio.2023.102919
Engineering a universal and efficient platform for terpenoid synthesis in yeast
- Yongshuo Ma, Yuexuan Zu, Sanwen Huang, …, Yuexuan Zu, Sanwen Huang, Gregory Stephanopoulos
- Proc Natl Acad Sci U S A, 10.1073/pnas.2207680120
Biosynthesis of geranate via isopentenol utilization pathway in Escherichia coli
- Qiuchi Pan, Xiaoqiang Ma, Hong Liang, …, Ying Zhou, Gregory Stephanopoulos, Kang Zhou
- Biotechnol Bioeng, 10.1002/bit.28255
Isotope tracing in health and disease
- Wentao Dong, Eshaan S Rawat, Gregory Stephanopoulos, …, Eshaan S Rawat, Gregory Stephanopoulos, Monther Abu-Remaileh
- Curr Opin Biotechnol, 10.1016/j.copbio.2022.102739
Optimization of the Isopentenol Utilization Pathway for Isoprenoid Synthesis in Escherichia coli
- Xiaoqiang Ma, Hong Liang, Qiuchi Pan, …, Anthony J Sinskey, Gregory Stephanopoulos, Kang Zhou
- J Agric Food Chem, 10.1021/acs.jafc.2c00014
Removal of lycopene substrate inhibition enables high carotenoid productivity in Yarrowia lipolytica
- Yongshuo Ma, Nian Liu, Per Greisen, …, Kangjian Qiao, Sanwen Huang, Gregory Stephanopoulos
- Nat Commun, 10.1038/s41467-022-28277-w
Insulin resistance rewires the metabolic gene program and glucose utilization in human white adipocytes
- Marie S Isidor, Wentao Dong, Rogelio I Servin-Uribe, …, Gregory Stephanopoulos, YazmÃn Macotela, Brice Emanuelli
- Int J Obes (Lond), 10.1038/s41366-021-01021-y
Targeting pathway expression to subcellular organelles improves astaxanthin synthesis in Yarrowia lipolytica
- Yongshuo Ma, Jingbo Li, Sanwen Huang, Gregory Stephanopoulos
- Metab Eng, 10.1016/j.ymben.2021.10.004
Engineered yeast tolerance enables efficient production from toxified lignocellulosic feedstocks
- Felix H Lam, Burcu Turanlı-Yıldız, Dany Liu, Michael G Resch, Gerald R Fink, Gregory Stephanopoulos
- Sci Adv, 10.1126/sciadv.abf7613
Partitioning metabolism between growth and product synthesis for coordinated production of wax esters in Acinetobacter baylyi ADP1
- Suvi Santala, Ville Santala, Nian Liu, Gregory Stephanopoulos
- Biotechnol Bioeng, 10.1002/bit.27740
Enzymes in biotechnology: Critical platform technologies for bioprocess development
- Constantinos Katsimpouras, Gregory Stephanopoulos
- Curr Opin Biotechnol, 10.1016/j.copbio.2020.12.003
Synthesis of high-titer alka(e)nes in Yarrowia lipolytica is enabled by a discovered mechanism
- Jingbo Li, Yongshuo Ma, Nian Liu, …, Zheng Guo, Peter Ruhdal Jensen, Gregory Stephanopoulos
- Nat Commun, 10.1038/s41467-020-19995-0
Constructing an ethanol utilization pathway in Escherichia coli to produce acetyl-CoA derived compounds
- Hong Liang, Xiaoqiang Ma, Wenbo Ning, …, Anthony J Sinskey, Gregory Stephanopoulos, Kang Zhou
- Metab Eng, 10.1016/j.ymben.2020.11.010
Oxidative pentose phosphate pathway and glucose anaplerosis support maintenance of mitochondrial NADPH pool under mitochondrial oxidative stress
- Sun Jin Moon, Wentao Dong, Gregory N Stephanopoulos, Hadley D Sikes
- None, 10.1002/btm2.10184
Metabolic engineering strategies to overcome precursor limitations in isoprenoid biosynthesis
- Yuexuan Zu, Kristala Lj Prather, Gregory Stephanopoulos
- Curr Opin Biotechnol, 10.1016/j.copbio.2020.07.005
Improving CRISPR/Cas9-mediated genome editing efficiency in Yarrowia lipolytica using direct tRNA-sgRNA fusions
- A M Abdel-Mawgoud, G Stephanopoulos
- Metab Eng, 10.1016/j.ymben.2020.07.008
Enhancing isoprenoid synthesis in Yarrowia lipolytica by expressing the isopentenol utilization pathway and modulating intracellular hydrophobicity
- Zhengshan Luo, Nian Liu, Zbigniew Lazar, …, Jian Chen, Jingwen Zhou, Gregory Stephanopoulos
- Metab Eng, 10.1016/j.ymben.2020.07.010
Protein engineering strategies for microbial production of isoprenoids
- Georgios Daletos, Gregory Stephanopoulos
- Metab Eng, 10.1016/j.mec.2020.e00129
Aldehyde dehydrogenase 3a2 protects AML cells from oxidative death and the synthetic lethality of ferroptosis inducers
- Rushdia Zareen Yusuf, Borja Saez, Azeem Sharda, …, Gregory Stephanopoulos, William B Rizzo, David T Scadden
- Blood, 10.1182/blood.2019001808
Novel Strategies and Platforms for Industrial Isoprenoid Engineering
- Georgios Daletos, Constantinos Katsimpouras, Gregory Stephanopoulos
- Trends Biotechnol, 10.1016/j.tibtech.2020.03.009
Using biopolymer bodies for encapsulation of hydrophobic products in bacterium
- Yurou Liu, Zhen Jie Low, Xiaoqiang Ma, …, Anthony J Sinskey, Gregory Stephanopoulos, Kang Zhou
- Metab Eng, 10.1016/j.ymben.2020.04.006
Critical Roles of the Pentose Phosphate Pathway and GLN3 in Isobutanol-Specific Tolerance in Yeast
- Kouichi Kuroda, Sarah K Hammer, Yukio Watanabe, …, Gregory Stephanopoulos, Mitsuyoshi Ueda, José L Avalos
- Cell Syst, 10.1016/j.cels.2019.10.006
Engineering Yarrowia lipolytica for the utilization of acid whey
- Junichi Mano, Nian Liu, John H Hammond, Devin H Currie, Gregory Stephanopoulos
- Metab Eng, 10.1016/j.ymben.2019.09.010
Cell free biosynthesis of isoprenoids from isopentenol
- Valerie C A Ward, Alkiviadis Orfefs Chatzivasileiou, Gregory Stephanopoulos
- Biotechnol Bioeng, 10.1002/bit.27146
Engineering Corynebacterium glutamicum for high-titer biosynthesis of hyaluronic acid
- Fangyu Cheng, Huimin Yu, Gregory Stephanopoulos
- Metab Eng, 10.1016/j.ymben.2019.07.003
Limitations in converting waste gases to fuels and chemicals
- David Frederic Emerson, Gregory Stephanopoulos
- Curr Opin Biotechnol, 10.1016/j.copbio.2019.02.004
