Interpreting non-coding disease-associated human variants using single-cell epigenomics
- Kyle J Gaulton, Kyle J Gaulton, Kyle J Gaulton, …, Kyle J Gaulton, Sebastian Preissl, Bing Ren
- Nat Rev Genet, 10.1038/s41576-023-00598-6
Integrated analysis of single-cell chromatin state and transcriptome identified common vulnerability despite glioblastoma heterogeneity
- Ramya Raviram, Anugraha Raman, Sebastian Preissl, …, Laure Escoubet, Bing Ren, Clark C Chen
- Proc Natl Acad Sci U S A, 10.1073/pnas.2210991120
Topologically associating domain boundaries are required for normal genome function
- Sudha Rajderkar, Iros Barozzi, Yiwen Zhu, …, Diane E Dickel, Axel Visel, Len A Pennacchio
- Commun Biol, 10.1038/s42003-023-04819-w
Comparative single cell epigenomic analysis of gene regulatory programs in the rodent and primate neocortex
- Nathan R Zemke, Ethan J Armand, Wenliang Wang, …, Ed S Lein, Joseph R Ecker, Bing Ren
- None, 10.1101/2023.04.08.536119
The EN-TEx resource of multi-tissue personal epigenomes & variant-impact models
- Joel Rozowsky, Jiahao Gao, Beatrice Borsari, …, Roderic Guigó, Thomas R Gingeras, Mark Gerstein
- Cell, 10.1016/j.cell.2023.02.018
Age-dependent Lamin changes induce cardiac dysfunction via dysregulation of cardiac transcriptional programs
- Natalie J Kirkland, Scott H Skalak, Alexander J Whitehead, …, Bing Ren, Rolf Bodmer, Adam J Engler
- Nat Aging, 10.1038/s43587-022-00323-8
Human-gained heart enhancers are associated with species-specific cardiac attributes
- Eugin Destici, Fugui Zhu, Shaina Tran, …, Bing Ren, Chris Benner, Neil C Chi
- None, 10.1038/s44161-022-00124-7
Single-Cell Joint Profiling of Open Chromatin and Transcriptome by Paired-Seq
- Chenxu Zhu, Zhaoning Wang, Bing Ren, …, Chenxu Zhu, Zhaoning Wang, Bing Ren
- Methods Mol Biol, 10.1007/978-1-0716-2899-7_10
Type 1 diabetes risk genes mediate pancreatic beta cell survival in response to proinflammatory cytokines
- Paola Benaglio, Han Zhu, Mei-Lin Okino, …, Kelly A Frazer, Maike Sander, Kyle J Gaulton
- None, 10.1016/j.xgen.2022.100214
Author Correction: A spatial genome aligner for resolving chromatin architectures from multiplexed DNA FISH
- Bojing Blair Jia, Adam Jussila, Colin Kern, …, Colin Kern, Quan Zhu, Bing Ren
- Nat Biotechnol, 10.1038/s41587-023-01673-3
Systematic discovery and functional dissection of enhancers needed for cancer cell fitness and proliferation
- Poshen B Chen, Patrick C Fiaux, Kai Zhang, …, Graham McVicker, Paul S Mischel, Bing Ren
- Cell Rep, 10.1016/j.celrep.2022.111630
Single-cell epigenome analysis reveals age-associated decay of heterochromatin domains in excitatory neurons in the mouse brain
- Yanxiao Zhang, Maria Luisa Amaral, Chenxu Zhu, …, Sebastian Preissl, Xiangmin Xu, Bing Ren
- Cell Res, 10.1038/s41422-022-00719-6
Bridging between Mouse and Human Enhancer-Promoter Long-Range Interactions in Neural Stem Cells, to Understand Enhancer Function in Neurodevelopmental Disease
- Romina D’Aurizio, Orazio Catona, Mattia Pitasi, Yang Eric Li, Bing Ren, Silvia Kirsten Nicolis
- Int J Mol Sci, 10.3390/ijms23147964
Characterizing cis-regulatory elements using single-cell epigenomics
- Kyle J Gaulton, Kyle J Gaulton, Kyle J Gaulton, …, Sebastian Preissl, Kyle J Gaulton, Bing Ren
- Nat Rev Genet, 10.1038/s41576-022-00509-1
The Hippo pathway mediates Semaphorin signaling
- Zhipeng Meng, Fu-Long Li, Cao Fang, …, Bing Ren, Adam J Engler, Kun-Liang Guan
- Sci Adv, 10.1126/sciadv.abl9806
