Academic lineage
Mutualism reduces the severity of gene disruptions in predictable ways across microbial communities
- Jonathan N V Martinson, Jeremy M Chacón, Brian A Smith, …, Alex R Villarreal, Ryan C Hunter, William R Harcombe
- None, 10.1101/2023.05.08.539835
Harnessing intercellular signals to engineer the soil microbiome
- Jack A Connolly, William R Harcombe, Michael J Smanski, Linda L Kinkel, Eriko Takano, Rainer Breitling
- Nat Prod Rep, 10.1039/d1np00034a
A metabolic modeling platform for the computation of microbial ecosystems in time and space (COMETS)
- Ilija Dukovski, Djordje Bajić, Jeremy M Chacón, …, Alvaro Sanchez, William R Harcombe, Daniel Segrè
- Nat Protoc, 10.1038/s41596-021-00593-3
Conformational rearrangements enable iterative backbone N-methylation in RiPP biosynthesis
- Fredarla S Miller, Kathryn K Crone, Matthew R Jensen, …, William R Harcombe, Mikael H Elias, Michael F Freeman
- Nat Commun, 10.1038/s41467-021-25575-7
Limitation by a shared mutualist promotes coexistence of multiple competing partners
- Sarah P Hammarlund, Tomáš Gedeon, Ross P Carlson, William R Harcombe
- Nat Commun, 10.1038/s41467-021-20922-0
Weakest-Link Dynamics Predict Apparent Antibiotic Interactions in a Model Cross-Feeding Community
- Elizabeth M Adamowicz, William R Harcombe
- Antimicrob Agents Chemother, 10.1128/aac.00465-20
Disruption of Cross-Feeding Inhibits Pathogen Growth in the Sputa of Patients with Cystic Fibrosis
- Jeffrey M Flynn, Lydia C Cameron, Talia D Wiggen, Jordan M Dunitz, William R Harcombe, Ryan C Hunter
- mSphere, 10.1128/msphere.00343-20
Increasing growth rate slows adaptation when genotypes compete for diffusing resources
- Jeremy M Chacón, Allison K Shaw, William R Harcombe
- PLoS Comput Biol, 10.1371/journal.pcbi.1007585
Lytic bacteriophage have diverse indirect effects in a synthetic cross-feeding community
- Lisa Fazzino, Jeremy Anisman, Jeremy M Chacón, Richard H Heineman, William R Harcombe
- ISME J, 10.1038/s41396-019-0511-z
Common principles and best practices for engineering microbiomes
- Christopher E Lawson, William R Harcombe, Roland Hatzenpichler, …, David G Weissbrodt, Daniel R Noguera, Katherine D McMahon
- Nat Rev Microbiol, 10.1038/s41579-019-0255-9
Genomewide Assessment of Mycobacterium tuberculosis Conditionally Essential Metabolic Pathways
- Yusuke Minato, Daryl M Gohl, Joshua M Thiede, …, William R Harcombe, Fumito Maruyama, Anthony D Baughn
- mSystems, 10.1128/msystems.00070-19