Single-cell analysis of senescent epithelia reveals targetable mechanisms promoting fibrosis
- Eoin D O’Sullivan, Katie J Mylonas, Rachel Bell, …, Laura Denby, Hassan Dihazi, David A Ferenbach
- JCI Insight, 10.1172/jci.insight.154124
Integrated methylome and phenome study of the circulating proteome reveals markers pertinent to brain health
- Danni A Gadd, Robert F Hillary, Daniel L McCartney, …, Heather C Whalley, Andrew M McIntosh, Riccardo E Marioni
- Nat Commun, 10.1038/s41467-022-32319-8
Longitudinal dynamics of clonal hematopoiesis identifies gene-specific fitness effects
- Neil A Robertson, Eric Latorre-Crespo, Maria Terradas-Terradas, …, Linus J Schumacher, Kristina Kirschner, Tamir Chandra
- Nat Med, 10.1038/s41591-022-01883-3
Tfap2b specifies an embryonic melanocyte stem cell that retains adult multifate potential
- Alessandro Brombin, Daniel J Simpson, Jana Travnickova, …, Adelaide I J Young, Tamir Chandra, E Elizabeth Patton
- Cell Rep, 10.1016/j.celrep.2021.110234
Cellular reprogramming and epigenetic rejuvenation
- Daniel J Simpson, Nelly N Olova, Tamir Chandra
- Clin Epigenetics, 10.1186/s13148-021-01158-7
Clonal haematopoiesis of indeterminate potential: intersections between inflammation, vascular disease and heart failure
- Leanne Mooney, Carl S Goodyear, Tamir Chandra, …, Mhairi Copland, Mark C Petrie, Ninian N Lang
- Clin Sci (Lond), 10.1042/cs20200306
Kidney Single-Cell Atlas Reveals Myeloid Heterogeneity in Progression and Regression of Kidney Disease
- Bryan R Conway, Eoin D O’Sullivan, Carolynn Cairns, …, Jeremy Hughes, Tamir Chandra, Laura Denby
- J Am Soc Nephrol, 10.1681/asn.2020060806
Induction and transmission of oncogene-induced senescence
- Nattaphong Rattanavirotkul, Kristina Kirschner, Tamir Chandra
- Cell Mol Life Sci, 10.1007/s00018-020-03638-0
An epigenome-wide association study of sex-specific chronological ageing
- Daniel L McCartney, Futao Zhang, Robert F Hillary, …, Peter M Visscher, Allan F McRae, Riccardo E Marioni
- Genome Med, 10.1186/s13073-019-0693-z