Multifactor transcriptional control of alternative oxidase induction integrates diverse environmental inputs to enable fungal virulence
- Zhongle Liu, Pauline Basso, Saif Hossain, …, Luke Whitesell, Suzanne M Noble, Leah E Cowen
- Nat Commun, 10.1038/s41467-023-40209-w
Ent2 Governs Morphogenesis and Virulence in Part through Regulation of the Cdc42 Signaling Cascade in the Fungal Pathogen Candida albicans
- Emma Lash, Victoria Prudent, Peter J Stogios, …, Suzanne M Noble, Nicole Robbins, Leah E Cowen
- mBio, 10.1128/mbio.03434-22
Deep tissue infection by an invasive human fungal pathogen requires lipid-based suppression of the IL-17 response
- Pauline Basso, Eric V Dang, Anatoly Urisman, …, Leah E Cowen, Hiten D Madhani, Suzanne M Noble
- Cell Host Microbe, 10.1016/j.chom.2022.10.004
Candida albicans oscillating UME6 expression during intestinal colonization primes systemic Th17 protective immunity
- Tzu-Yu Shao, Pallavi Kakade, Jessica N Witchley, …, Suzanne M Noble, Richard J Bennett, Sing Sing Way
- Cell Rep, 10.1016/j.celrep.2022.110837
Leveraging machine learning essentiality predictions and chemogenomic interactions to identify antifungal targets
- Ci Fu, Xiang Zhang, Amanda O Veri, …, Nicole Robbins, Chad L Myers, Leah E Cowen
- Nat Commun, 10.1038/s41467-021-26850-3
Adaptive immunity induces mutualism between commensal eukaryotes
- Kyla S Ost, Teresa R O’Meara, W Zac Stephens, …, Noah W Palm, Suzanne M Noble, June L Round
- Nature, 10.1038/s41586-021-03722-w
Recording of DNA-binding events reveals the importance of a repurposed Candida albicans regulatory network for gut commensalism
- Jessica N Witchley, Pauline Basso, Cedric A Brimacombe, Nina V Abon, Suzanne M Noble
- Cell Host Microbe, 10.1016/j.chom.2021.03.019
A natural histone H2A variant lacking the Bub1 phosphorylation site and regulated depletion of centromeric histone CENP-A foster evolvability in Candida albicans
- Cedric A Brimacombe, Jordan E Burke, Jahan-Yar Parsa, …, Laura S Burrack, Hiten D Madhani, Suzanne M Noble
- PLoS Biol, 10.1371/journal.pbio.3000331
Candida albicans Morphogenesis Programs Control the Balance between Gut Commensalism and Invasive Infection
- Jessica N Witchley, Pallavi Penumetcha, Nina V Abon, Carol A Woolford, Aaron P Mitchell, Suzanne M Noble
- Cell Host Microbe, 10.1016/j.chom.2019.02.008
Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections
- Chao Tian, Bethann S Hromatka, Amy K Kiefer, …, Suzanne M Noble, Joyce Y Tung, David A Hinds
- Nat Commun, 10.1038/s41467-017-00257-5
Candida albicans cell-type switching and functional plasticity in the mammalian host
- Suzanne M Noble, Brittany A Gianetti, Jessica N Witchley
- Nat Rev Microbiol, 10.1038/nrmicro.2016.157
Candida albicans specializations for iron homeostasis: from commensalism to virulence
- Suzanne M Noble
- Curr Opin Microbiol, 10.1016/j.mib.2013.09.006