A complex of Wnt/planar cell polarity signaling components Vangl1 and Fzd7 drives glioblastoma multiforme malignant properties
- Courtney A Dreyer, Kacey VanderVorst, Dean Natwick, …, James M Angelastro, Sean R Collins, Kermit L Carraway
- Cancer Lett, 10.1016/j.canlet.2023.216280
Vangl-dependent Wnt/planar cell polarity signaling mediates collective breast carcinoma motility and distant metastasis
- Kacey VanderVorst, Courtney A Dreyer, Jason Hatakeyama, …, Hyun Lee, Sean R Collins, Kermit L Carraway
- Breast Cancer Res, 10.1186/s13058-023-01651-2
Leading edge competition promotes context-dependent responses to receptor inputs to resolve directional dilemmas in neutrophil migration
- Amalia Hadjitheodorou, George R R Bell, Felix Ellett, …, Robert Tibshirani, Sean R Collins, Julie A Theriot
- Cell Syst, 10.1016/j.cels.2023.02.001
Flagella-driven motility is a target of human Paneth cell defensin activity
- Douglas T Akahoshi, Dean E Natwick, Weirong Yuan, …, Wuyuan Lu, Sean R Collins, Charles L Bevins
- PLoS Pathog, 10.1371/journal.ppat.1011200
Host cells subdivide nutrient niches into discrete biogeographical microhabitats for gut microbes
- Megan J Liou, Brittany M Miller, Yael Litvak, …, Mariana X Byndloss, Scott I Simon, Andreas J Bäumler
- Cell Host Microbe, 10.1016/j.chom.2022.04.012
WASP integrates substrate topology and cell polarity to guide neutrophil migration
- Rachel M Brunetti, Gabriele Kockelkoren, Preethi Raghavan, …, Manuel D Leonetti, Dimitrios Stamou, Orion D Weiner
- J Cell Biol, 10.1083/jcb.202104046
Directional reorientation of migrating neutrophils is limited by suppression of receptor input signaling at the cell rear through myosin II activity
- Amalia Hadjitheodorou, George R R Bell, Felix Ellett, …, Daniel Irimia, Sean R Collins, Julie A Theriot
- Nat Commun, 10.1038/s41467-021-26622-z
Optogenetic control of receptors reveals distinct roles for actin- and Cdc42-dependent negative signals in chemotactic signal processing
- George R R Bell, Esther Rincón, Emel AkdoÄŸan, …, Esther Rincón, Emel AkdoÄŸan, Sean R Collins
- Nat Commun, 10.1038/s41467-021-26371-z
Optimized iLID Membrane Anchors for Local Optogenetic Protein Recruitment
- Dean E Natwick, Sean R Collins
- ACS Synth Biol, 10.1021/acssynbio.0c00511
SUMO is a pervasive regulator of meiosis
- Nikhil R Bhagwat, Shannon N Owens, Masaru Ito, …, Jeffrey R Johnson, Nevan J Krogan, Neil Hunter
- Elife, 10.7554/elife.57720
Decoding GEFs of animated cells
- Dean E Natwick, Sean R Collins
- Nat Chem Biol, 10.1038/s41589-020-0570-5
Efficient Front-Rear Coupling in Neutrophil Chemotaxis by Dynamic Myosin II Localization
- Tony Y-C Tsai, Sean R Collins, Caleb K Chan, …, Tobias Meyer, James E Ferrell, Julie A Theriot
- Dev Cell, 10.1016/j.devcel.2019.03.025
Identification of phagocytosis regulators using magnetic genome-wide CRISPR screens
- Michael S Haney, Christopher J Bohlen, David W Morgens, …, Sean R Collins, Ben A Barres, Michael C Bassik
- Nat Genet, 10.1038/s41588-018-0254-1