Academic lineage
Adaptations in metabolism and protein translation give rise to the Crabtree effect in yeast
- Carl Malina, Rosemary Yu, Johan Björkeroth, Eduard J Kerkhoven, Jens Nielsen
- Proc Natl Acad Sci U S A, 10.1073/pnas.2112836118
Yeast metabolic innovations emerged via expanded metabolic network and gene positive selection
- Hongzhong Lu, Feiran Li, Le Yuan, …, Boyang Ji, Eduard J Kerkhoven, Jens Nielsen
- Mol Syst Biol, 10.15252/msb.202110427
A single chromosome strain of S. cerevisiae exhibits diminished ethanol metabolism and tolerance
- Tyler W Doughty, Rosemary Yu, Lucy Fang-I Chao, Zhongjun Qin, Verena Siewers, Jens Nielsen
- BMC Genomics, 10.1186/s12864-021-07947-x
Quantifying absolute gene expression profiles reveals distinct regulation of central carbon metabolism genes in yeast
- Rosemary Yu, Egor Vorontsov, Carina Sihlbom, Jens Nielsen
- Elife, 10.7554/elife.65722
Different Routes of Protein Folding Contribute to Improved Protein Production in Saccharomyces cerevisiae
- Qi Qi, Feiran Li, Rosemary Yu, …, Verena Siewers, Johannes Fuchs, Jens Nielsen
- mBio, 10.1128/mbio.02743-20
Proteome reallocation from amino acid biosynthesis to ribosomes enables yeast to grow faster in rich media
- Johan Björkeroth, Kate Campbell, Carl Malina, Rosemary Yu, Francesca Di Bartolomeo, Jens Nielsen
- Proc Natl Acad Sci U S A, 10.1073/pnas.1921890117
Nitrogen limitation reveals large reserves in metabolic and translational capacities of yeast
- Rosemary Yu, Kate Campbell, Rui Pereira, …, Egor Vorontsov, Carina Sihlbom, Jens Nielsen
- Nat Commun, 10.1038/s41467-020-15749-0
Yeast systems biology in understanding principles of physiology underlying complex human diseases
- Rosemary Yu, Jens Nielsen
- Curr Opin Biotechnol, 10.1016/j.copbio.2019.11.021
An actionable sterol-regulated feedback loop modulates statin sensitivity in prostate cancer
- Joseph Longo, Peter J Mullen, Rosemary Yu, …, Theodorus H van der Kwast, Neil E Fleshner, Linda Z Penn
- Mol Metab, 10.1016/j.molmet.2019.04.003
Genome-wide RNAi analysis reveals that simultaneous inhibition of specific mevalonate pathway genes potentiates tumor cell death
- Aleksandra A Pandyra, Peter J Mullen, Carolyn A Goard, …, Corey Nislow, Jason Moffat, Linda Z Penn
- Oncotarget, 10.18632/oncotarget.4817