Academic lineage
- Bernhard Ø Palsson - Postdoctoral Associate
Identification of the Biosynthetic Gene Cluster for Pyracrimycin A, an Antibiotic Produced by Streptomyces sp
- Julie B Nielsen, Tetiana Gren, Omkar S Mohite, …, Tilmann Weber, Charlotte H Gotfredsen, Pep Charusanti
- ACS Chem Biol, 10.1021/acschembio.2c00480
Complete Genome Sequence of the Rare Actinobacterium Kutzneria sp. Strain CA-103260
- Tue S Jørgensen, Tetiana Gren, Eftychia E Kontou, …, Pep Charusanti, Olga Genilloud, Tilmann Weber
- None, 10.1128/mra.00499-21
Discovery and Characterization of Epemicins A and B, New 30-Membered Macrolides from Kutzneria sp. CA-103260
- Eftychia Eva Kontou, Tetiana Gren, Francisco Javier Ortiz-López, …, Fernando Reyes, Olga Genilloud, Tilmann Weber
- ACS Chem Biol, 10.1021/acschembio.1c00318
Programmable polyketide biosynthesis platform for production of aromatic compounds in yeast
- Tadas Jakočiūnas, Andreas K Klitgaard, Eftychia Eva Kontou, …, Sang Yup Lee, Michael K Jensen, Jay D Keasling
- None, 10.1016/j.synbio.2020.01.004
Challenges and advances in genetic manipulation of filamentous actinomycetes – the remarkable producers of specialized metabolites
- Ewa M Musiol-Kroll, Arianna Tocchetti, Margherita Sosio, Evi Stegmann
- Nat Prod Rep, 10.1039/c9np00029a
Dissemination of antibiotic resistance genes from antibiotic producers to pathogens
- Xinglin Jiang, Mostafa M Hashim Ellabaan, Pep Charusanti, …, Tilmann Weber, Morten O A Sommer, Sang Yup Lee
- Nat Commun, 10.1038/ncomms15784
The aldehyde dehydrogenase, AldA, is essential for L-1,2-propanediol utilization in laboratory-evolved Escherichia coli
- Ramy K Aziz, Jonathan M Monk, Kathleen A Andrews, …, Hesper Wong, Bernhard O Palsson, Pep Charusanti
- Microbiol Res, 10.1016/j.micres.2016.10.006
Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking
- Mingxun Wang, Jeremy J Carver, Vanessa V Phelan, …, Bradley S Moore, Pieter C Dorrestein, Nuno Bandeira
- Nat Biotechnol, 10.1038/nbt.3597
Metabolic engineering with systems biology tools to optimize production of prokaryotic secondary metabolites
- Hyun Uk Kim, Pep Charusanti, Sang Yup Lee, Tilmann Weber
- Nat Prod Rep, 10.1039/c6np00019c
Systems biology-guided identification of synthetic lethal gene pairs and its potential use to discover antibiotic combinations
- Ramy K Aziz, Jonathan M Monk, Robert M Lewis, …, Howard J Li, Bernhard O Palsson, Pep Charusanti
- Sci Rep, 10.1038/srep16025
Model-driven discovery of synergistic inhibitors against E. coli and S. enterica serovar Typhimurium targeting a novel synthetic lethal pair, aldA and prpC
- Ramy K Aziz, Valerie L Khaw, Jonathan M Monk, …, Kathleen A Andrews, Bernhard Ø Palsson, Pep Charusanti
- None, 10.3389/fmicb.2015.00958
Systems biology definition of the core proteome of metabolism and expression is consistent with high-throughput data
- Laurence Yang, Justin Tan, Edward J O’Brien, …, Yuekai Sun, Michael A Saunders, Bernhard O Palsson
- Proc Natl Acad Sci U S A, 10.1073/pnas.1501384112
CRISPR-Cas9 Based Engineering of Actinomycetal Genomes
- Yaojun Tong, Pep Charusanti, Lixin Zhang, Tilmann Weber, Sang Yup Lee
- ACS Synth Biol, 10.1021/acssynbio.5b00038
Metabolic engineering of antibiotic factories: new tools for antibiotic production in actinomycetes
- Tilmann Weber, Pep Charusanti, Ewa Maria Musiol-Kroll, …, Yaojun Tong, Hyun Uk Kim, Sang Yup Lee
- Trends Biotechnol, 10.1016/j.tibtech.2014.10.009
Understanding system dynamics of an adaptive enzyme network from globally profiled kinetic parameters
- Austin W T Chiang, Wei-Chung Liu, Pep Charusanti, Ming-Jing Hwang
- None, 10.1186/1752-0509-8-4