Cell-cell metabolite exchange creates a pro-survival metabolic environment that extends lifespan
- Clara Correia-Melo, Stephan Kamrad, Roland Tengölics, …, Balázs Papp, Mohammad Tauqeer Alam, Markus Ralser
- Cell, 10.1016/j.cell.2022.12.007
Nfkb2 deficiency and its impact on plasma cells and immunoglobulin expression in murine small intestinal mucosa
- Stamatia Papoutsopoulou, Joseph Tang, Ahmed H Elramli, …, Werner Muller, Carrie A Duckworth, D Mark Pritchard
- Am J Physiol Gastrointest Liver Physiol, 10.1152/ajpgi.00037.2022
Posttranscriptional Regulation in Response to Different Environmental Stresses in Campylobacter jejuni
- Stephen Li, Jenna Lam, Leonidas Souliotis, Mohammad Tauqeer Alam, Chrystala Constantinidou
- Microbiol Spectr, 10.1128/spectrum.00203-22
Effects of Human RelA Transgene on Murine Macrophage Inflammatory Responses
- Stamatia Papoutsopoulou, Lorna Morris, Andrew Bayliff, …, Werner Müller, Vitor A P Martins Dos Santos, Barry J Campbell
- None, 10.3390/biomedicines10040757
Microbial communities form rich extracellular metabolomes that foster metabolic interactions and promote drug tolerance
- Jason S L Yu, Clara Correia-Melo, Francisco Zorrilla, …, Kiran R Patil, Mohammad Tauqeer Alam, Markus Ralser
- Nat Microbiol, 10.1038/s41564-022-01072-5
Genomic assessment of quarantine measures to prevent SARS-CoV-2 importation and transmission
- Dinesh Aggarwal, Andrew J Page, Ulf Schaefer, …, Sharon J Peacock, Meera Chand, Ewan M Harrison
- Nat Commun, 10.1038/s41467-022-28371-z
Genomic epidemiology of SARS-CoV-2 in a UK university identifies dynamics of transmission
- Dinesh Aggarwal, Ben Warne, Aminu S Jahun, …, Ewan M Harrison, Nicholas J Matheson, Ian G Goodfellow
- Nat Commun, 10.1038/s41467-021-27942-w
Exponential growth, high prevalence of SARS-CoV-2, and vaccine effectiveness associated with the Delta variant
- Paul Elliott, David Haw, Haowei Wang, …, Helen Ward, Ara Darzi, Steven Riley
- Science, 10.1126/science.abl9551
Hospital admission and emergency care attendance risk for SARS-CoV-2 delta (B.1.617.2) compared with alpha (B.1.1.7) variants of concern: a cohort study
- Katherine A Twohig, Tommy Nyberg, Asad Zaidi, …, Daniela De Angelis, Anne M Presanis, Gavin Dabrera
- Lancet Infect Dis, 10.1016/s1473-3099(21)00475-8
Impact of Interleukin 10 Deficiency on Intestinal Epithelium Responses to Inflammatory Signals
- Stamatia Papoutsopoulou, Liam Pollock, Catherine Walker, …, Vitor A P Martins Dos Santos, Werner Müller, Barry J Campbell
- Front Immunol, 10.3389/fimmu.2021.690817
Recurrent emergence of SARS-CoV-2 spike deletion H69/V70 and its role in the Alpha variant B.1.1.7
- Bo Meng, Steven A Kemp, Guido Papa, …, David L Robertson, Dalan Bailey, Ravindra K Gupta
- Cell Rep, 10.1016/j.celrep.2021.109292
Identification of an RNA sponge that controls the RoxS riboregulator of central metabolism in Bacillus subtilis
- Sylvain Durand, Adam Callan-Sidat, Josie McKeown, …, Chrystala Constantinidou, Ciarán Condon, Emma L Denham
- Nucleic Acids Res, 10.1093/nar/gkab444
Performance of the faecal immunochemical test for the detection of colorectal neoplasms and the role of proton pump inhibitors in their diagnostic accuracy
- Subashini Chandrapalan, Siew Wan Hee, Monika M Widlak, …, Mohammed T Alam, Steve Smith, Ramesh P Arasaradnam
- Colorectal Dis, 10.1111/codi.15735
Changes in symptomatology, reinfection, and transmissibility associated with the SARS-CoV-2 variant B.1.1.7: an ecological study
- Mark S Graham, Carole H Sudre, Anna May, …, Tim D Spector, Claire J Steves, Sebastien Ourselin
- Lancet Public Health, 10.1016/s2468-2667(21)00055-4
SARS-CoV-2 B.1.1.7 sensitivity to mRNA vaccine-elicited, convalescent and monoclonal antibodies
- Dami A Collier, Anna De Marco, Isabella A T M Ferreira, …, David Veesler, Davide Corti, Ravindra K Gupta
- None, 10.1101/2021.01.19.21249840
SARS-CoV-2 evolution during treatment of chronic infection
- Steven A Kemp, Dami A Collier, Rawlings P Datir, …, Christopher J R Illingworth, Laura E McCoy, Ravindra K Gupta
- Nature, 10.1038/s41586-021-03291-y
Evaluating the Effects of SARS-CoV-2 Spike Mutation D614G on Transmissibility and Pathogenicity
- Erik Volz, Verity Hill, John T McCrone, …, Emma C Thomson, Andrew Rambaut, Thomas R Connor
- Cell, 10.1016/j.cell.2020.11.020
The pathophysiology of bile acid diarrhoea: differences in the colonic microbiome, metabolome and bile acids
- Nidhi M Sagar, Henri Duboc, Gemma L Kay, …, Konstantinos Gerasimidis, Julian R F Walters, Ramesh P Arasaradnam
- Sci Rep, 10.1038/s41598-020-77374-7
The type VII secretion system protects Staphylococcus aureus against antimicrobial host fatty acids
- Arnaud Kengmo Tchoupa, Kate E Watkins, Rebekah A Jones, …, Sebastien Perrier, Yin Chen, Meera Unnikrishnan
- Sci Rep, 10.1038/s41598-020-71653-z
Microbial imbalance in inflammatory bowel disease patients at different taxonomic levels
- Mohammad Tauqeer Alam, Gregory C A Amos, Andrew R J Murphy, Simon Murch, Elizabeth M H Wellington, Ramesh P Arasaradnam
- None, 10.1186/s13099-019-0341-6
Lysine harvesting is an antioxidant strategy and triggers underground polyamine metabolism
- Viridiana Olin-Sandoval, Jason Shu Lim Yu, Leonor Miller-Fleming, …, Jakob Vowinckel, Michael Mülleder, Markus Ralser
- Nature, 10.1038/s41586-019-1442-6
The self-inhibitory nature of metabolic networks and its alleviation through compartmentalization
- Mohammad Tauqeer Alam, Viridiana Olin-Sandoval, Anna Stincone, …, Aleksej Zelezniak, Ben F Luisi, Markus Ralser
- Nat Commun, 10.1038/ncomms16018
Cellular reactions to long-term volatile organic compound (VOC) exposures
- Johanna M Gostner, Johannes Zeisler, Mohammad Tauqeer Alam, …, Markus Kleinhappl, Stefan Martini, Florian Ãœberall
- Sci Rep, 10.1038/srep37842
Functional Metabolomics Describes the Yeast Biosynthetic Regulome
- Michael Mülleder, Enrica Calvani, Mohammad Tauqeer Alam, …, Florian Eckerstorfer, Aleksej Zelezniak, Markus Ralser
- Cell, 10.1016/j.cell.2016.09.007
The metabolic background is a global player in Saccharomyces gene expression epistasis
- Mohammad Tauqeer Alam, Aleksej Zelezniak, Michael Mülleder, …, Bernd Timmermann, Kathryn S Lilley, Markus Ralser
- Nat Microbiol, 10.1038/nmicrobiol.2015.30