Scholar: Michael Neinast

Michael Neinast

Academic lineage

Extra-cardiac BCAA catabolism lowers blood pressure and protects from heart failure

  • Danielle Murashige, Jae Woo Jung, Michael D Neinast, …, Cholsoon Jang, Joshua D Rabinowitz, Zoltan Arany
  • Cell Metab, 10.1016/j.cmet.2022.09.008
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Gut bacterial nutrient preferences quantified in vivo

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A randomized placebo-controlled clinical trial for pharmacological activation of BCAA catabolism in patients with type 2 diabetes

  • Froukje Vanweert, Michael Neinast, Edmundo Erazo Tapia, …, Patrick Schrauwen, Zoltan Arany, Esther Phielix
  • Nat Commun, 10.1038/s41467-022-31249-9
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Direct anabolic metabolism of three-carbon propionate to a six-carbon metabolite occurs in vivo across tissues and species

  • Mary T Doan, Michael D Neinast, Erika L Varner, …, Kenneth B Marguiles, Zoltan Arany, Nathaniel W Snyder
  • J Lipid Res, 10.1016/j.jlr.2022.100224
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Insulin-stimulated adipocytes secrete lactate to promote endothelial fatty acid uptake and transport

  • Ayon Ibrahim, Michael D Neinast, Kristina Li, …, Raffiu Mohammed, Kathryn E Wellen, Zoltan Arany
  • J Cell Sci, 10.1242/jcs.258964
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AKT controls protein synthesis and oxidative metabolism via combined mTORC1 and FOXO1 signalling to govern muscle physiology

  • Natasha Jaiswal, Matthew Gavin, Emanuele Loro, …, Scot R Kimball, Tejvir S Khurana, Paul M Titchenell
  • J Cachexia Sarcopenia Muscle, 10.1002/jcsm.12846
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Comprehensive quantification of fuel use by the failing and nonfailing human heart

  • Danielle Murashige, Cholsoon Jang, Michael Neinast, …, Joshua D Rabinowitz, David S Frankel, Zolt Arany
  • Science, 10.1126/science.abc8861
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Quantitative Analysis of the Whole-Body Metabolic Fate of Branched-Chain Amino Acids

  • Michael D Neinast, Cholsoon Jang, Sheng Hui, …, Tracy G Anthony, Joshua D Rabinowitz, Zoltan Arany
  • Cell Metab, 10.1016/j.cmet.2018.10.013
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Myobolites: muscle-derived metabolites with paracrine and systemic effects

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The tumor suppressor FLCN mediates an alternate mTOR pathway to regulate browning of adipose tissue

  • Shogo Wada, Michael Neinast, Cholsoon Jang, …, Joseph A Baur, Patrick Seale, Zoltan Arany
  • Genes Dev, 10.1101/gad.287953.116
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Activation of natriuretic peptides and the sympathetic nervous system following Roux-en-Y gastric bypass is associated with gonadal adipose tissues browning

  • Michael D Neinast, Aaron P Frank, Juliet F Zechner, …, Vincent Aguirre, Rana K Gupta, Deborah J Clegg
  • Mol Metab, 10.1016/j.molmet.2015.02.006
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