Scholar: Mark Ashe

Mark Ashe

Paralogous translation factors target distinct mRNAs to differentially regulate tolerance to oxidative stress in yeast

  • Joanne Cunningham, Aristeidis P Sfakianos, Paraskevi Kritsiligkou, …, Simon J Hubbard, Mark P Ashe, Chris M Grant
  • Nucleic Acids Res, 10.1093/nar/gkad568
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Yeast Protein Kinase A Isoforms: A Means of Encoding Specificity in the Response to Diverse Stress Conditions?

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Cytosolic aspartate aminotransferase moonlights as a ribosome-binding modulator of Gcn2 activity during oxidative stress

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Integrated multi-omics reveals common properties underlying stress granule and P-body formation

  • Christopher J Kershaw, Michael G Nelson, Jennifer Lui, …, Simon J Hubbard, Mark P Ashe, Chris M Grant
  • RNA Biol, 10.1080/15476286.2021.1976986
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Core Fermentation (CoFe) granules focus coordinated glycolytic mRNA localization and translation to fuel glucose fermentation

  • Fabian Morales-Polanco, Christian Bates, Jennifer Lui, …, Simon Hubbard, Paula Portela, Mark P Ashe
  • None, 10.1016/j.isci.2021.102069
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Mutational analysis of the alpha subunit of eIF2B provides insights into the role of eIF2B bodies in translational control and VWM disease

  • Karl Norris, Rachel E Hodgson, Tawni Dornelles, …, Ben M Abell, Mark P Ashe, Susan G Campbell
  • J Biol Chem, 10.1074/jbc.ra120.014956
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A prion-like domain of Tpk2 catalytic subunit of protein kinase A modulates P-body formation in response to stress in budding yeast

  • Carla E Barraza, Clara A Solari, Jimena Rinaldi, …, Silvia Rossi, Mark P Ashe, Paula Portela
  • Biochim Biophys Acta Mol Cell Res, 10.1016/j.bbamcr.2020.118884
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Extracellular Vesicles Isolated from Human Induced Pluripotent Stem Cell-Derived Neurons Contain a Transcriptional Network

  • David A Hicks, Alys C Jones, Nicola J Corbett, …, Stuart M Pickering-Brown, Mark P Ashe, Nigel M Hooper
  • Neurochem Res, 10.1007/s11064-020-03019-w
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Translation factor mRNA granules direct protein synthetic capacity to regions of polarized growth

  • Mariavittoria Pizzinga, Christian Bates, Jennifer Lui, …, Luke E Berchowitz, Paula Portela, Mark P Ashe
  • J Cell Biol, 10.1083/jcb.201704019
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Cellular eIF2B subunit localization: implications for the integrated stress response and its control by small molecule drugs

  • Rachel E Hodgson, Beatriz A Varanda, Mark P Ashe, …, Mark P Ashe, K Elizabeth Allen, Susan G Campbell
  • Mol Biol Cell, 10.1091/mbc.e18-08-0538
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Ribosomal flavours: an acquired taste for specific mRNAs?

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n-Butanol production in S. cerevisiae: co-ordinate use of endogenous and exogenous pathways

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Archetypal transcriptional blocks underpin yeast gene regulation in response to changes in growth conditions

  • David Talavera, Christopher J Kershaw, Joseph L Costello, …, Chris M Grant, Graham D Pavitt, Simon J Hubbard
  • Sci Rep, 10.1038/s41598-018-26170-5
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The mTOR-S6 kinase pathway promotes stress granule assembly

  • Aristeidis P Sfakianos, Laura E Mellor, Yoke Fei Pang, …, Gino B Poulin, Mark P Ashe, Alan J Whitmarsh
  • Cell Death Differ, 10.1038/s41418-018-0076-9
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Dynamic changes in eIF4F-mRNA interactions revealed by global analyses of environmental stress responses

  • Joseph L Costello, Christopher J Kershaw, Lydia M Castelli, …, Christopher M Grant, Simon J Hubbard, Graham D Pavitt
  • Genome Biol, 10.1186/s13059-017-1338-4
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The role of PKA in the translational response to heat stress in Saccharomyces cerevisiae

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Constitutively-stressed yeast strains are high-yielding for recombinant Fps1: implications for the translational regulation of an aquaporin

  • Stephanie P Cartwright, Richard A J Darby, Debasmita Sarkar, …, Stephane R Gross, Mark P Ashe, Roslyn M Bill
  • Microb Cell Fact, 10.1186/s12934-017-0656-2
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