Academic lineage
Viral Polymerase-Helicase Complexes Regulate Replication Fidelity To Overcome Intracellular Nucleotide Depletion
- Kenneth A Stapleford, Kathryn Rozen-Gagnon, Pratyush Kumar Das, …, Pierre-Olivier Vidalain, Andres Merits, Marco Vignuzzi
- J Virol, 10.1128/jvi.01553-15
Group Selection and Contribution of Minority Variants during Virus Adaptation Determines Virus Fitness and Phenotype
- Antonio V BorderĂa, Ofer Isakov, Gonzalo Moratorio, …, Magnus Fontes, Noam Shomron, Marco Vignuzzi
- PLoS Pathog, 10.1371/journal.ppat.1004838
Mutations in coronavirus nonstructural protein 10 decrease virus replication fidelity
- Everett Clinton Smith, James Brett Case, HervĂ© Blanc, …, Noam Shomron, Marco Vignuzzi, Mark R Denison
- J Virol, 10.1128/jvi.00110-15
Deep sequencing analysis of viral infection and evolution allows rapid and detailed characterization of viral mutant spectrum
- Ofer Isakov, Antonio V BorderĂa, David Golan, …, HervĂ© Blanc, Marco Vignuzzi, Noam Shomron
- Bioinformatics, 10.1093/bioinformatics/btv101
Phylogenetic and genome-wide deep-sequencing analyses of canine parvovirus reveal co-infection with field variants and emergence of a recent recombinant strain
- Ruben PĂ©rez, LucĂa Calleros, Ana Marandino, …, Katia Sosa, Gonzalo TomĂĄs, Yanina Panzera
- PLoS One, 10.1371/journal.pone.0111779
Structure-function relationships underlying the replication fidelity of viral RNA-dependent RNA polymerases
- Grace Campagnola, Seth McDonald, StĂ©phanie Beaucourt, …, StĂ©phanie Beaucourt, Marco Vignuzzi, Olve B Peersen
- J Virol, 10.1128/jvi.01574-14
RNA virus population diversity, an optimum for maximal fitness and virulence
- Victoria K Korboukh, Cheri A Lee, Ashley Acevedo, …, Avery August, Raul Andino, Craig E Cameron
- J Biol Chem, 10.1074/jbc.m114.592303
Emergence and transmission of arbovirus evolutionary intermediates with epidemic potential
- Kenneth A Stapleford, Lark L Coffey, Sreyrath Lay, …, Anna-Bella Failloux, Philippe Buchy, Marco Vignuzzi
- Cell Host Microbe, 10.1016/j.chom.2014.05.008
Ribavirin: a drug active against many viruses with multiple effects on virus replication and propagation. Molecular basis of ribavirin resistance
- Stéphanie Beaucourt, Marco Vignuzzi
- Curr Opin Virol, 10.1016/j.coviro.2014.04.011
Alphavirus mutator variants present host-specific defects and attenuation in mammalian and insect models
- Kathryn Rozen-Gagnon, Kenneth A Stapleford, Vanesa Mongelli, …, Anna-Bella Failloux, Maria-Carla Saleh, Marco Vignuzzi
- PLoS Pathog, 10.1371/journal.ppat.1003877
Coronaviruses lacking exoribonuclease activity are susceptible to lethal mutagenesis: evidence for proofreading and potential therapeutics
- Everett Clinton Smith, Hervé Blanc, Matthew C Surdel, Marco Vignuzzi, Mark R Denison
- PLoS Pathog, 10.1371/journal.ppat.1003565
Coxsackievirus B3 mutator strains are attenuated in vivo
- Nina F GnĂ€dig, StĂ©phanie Beaucourt, Grace Campagnola, …, HervĂ© Blanc, Olve B Peersen, Marco Vignuzzi
- Proc Natl Acad Sci U S A, 10.1073/pnas.1204022109
RNA virus population diversity: implications for inter-species transmission
- Antonio V BorderĂa, Kenneth A Stapleford, Marco Vignuzzi
- Curr Opin Virol, 10.1016/j.coviro.2011.09.012
Mutational robustness of an RNA virus influences sensitivity to lethal mutagenesis
- Jason D Graci, Nina F GnĂ€dig, Jessica E Galarraga, …, Christian Castro, Marco Vignuzzi, Craig E Cameron
- J Virol, 10.1128/jvi.05712-11
Arbovirus high fidelity variant loses fitness in mosquitoes and mice
- Lark L Coffey, Yasnee Beeharry, Antonio V BorderĂa, HervĂ© Blanc, Marco Vignuzzi
- Proc Natl Acad Sci U S A, 10.1073/pnas.1111650108
Fidelity variants of RNA dependent RNA polymerases uncover an indirect, mutagenic activity of amiloride compounds
- Laura I Levi, Nina F GnĂ€dig, StĂ©phanie Beaucourt, …, Bruno Baron, Jamie J Arnold, Marco Vignuzzi
- PLoS Pathog, 10.1371/journal.ppat.1001163