Human endogenous retrovirus onco-exaptation counters cancer cell senescence through calbindin
- Jan Attig, Judith Pape, Laura Doglio, …, Venizelos Papayannopoulos, Charles Swanton, George Kassiotis
- J Clin Invest, 10.1172/jci164397
Antibodies against endogenous retroviruses promote lung cancer immunotherapy
- Kevin W Ng, Jesse Boumelha, Katey S S Enfield, …, Charles Swanton, Julian Downward, George Kassiotis
- Nature, 10.1038/s41586-023-05771-9
B cell responses to the gut microbiota
- Kevin W Ng, Alvaro Hobbs, Christopher Wichmann, …, Christopher Wichmann, Gabriel D Victora, Gregory P Donaldson
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An Immunogenic Model of KRAS-Mutant Lung Cancer Enables Evaluation of Targeted Therapy and Immunotherapy Combinations
- Jesse Boumelha, Sophie de Carné Trécesson, Emily K Law, …, Charles Swanton, Reuben Harris, Julian Downward
- Cancer Res, 10.1158/0008-5472.can-22-0325
GREM1 is required to maintain cellular heterogeneity in pancreatic cancer
- Linxiang Lan, Theodore Evan, Huafu Li, …, Changhua Zhang, Anguraj Sadanandam, Axel Behrens
- Nature, 10.1038/s41586-022-04888-7
Functional antibody and T cell immunity following SARS-CoV-2 infection, including by variants of concern, in patients with cancer: the CAPTURE study
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Heterologous humoral immunity to human and zoonotic coronaviruses: Aiming for the achilles heel
- Kevin W Ng, Nikhil Faulkner, Antoni G Wrobel, …, Antoni G Wrobel, Steve J Gamblin, George Kassiotis
- Semin Immunol, 10.1016/j.smim.2021.101507
The molecular and cellular mechanisms associated with the destruction of terminal bronchioles in COPD
- Feng Xu, DragoÅŸ M Vasilescu, Daisuke Kinose, …, Don D Sin, Raymond T Ng, James C Hogg
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Favorable antibody responses to human coronaviruses in children and adolescents with autoimmune rheumatic diseases
- Claire T Deakin, Georgina H Cornish, Kevin W Ng, …, Coziana Ciurtin, Lucy R Wedderburn, George Kassiotis
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SARS-CoV-2 can recruit a heme metabolite to evade antibody immunity
- Annachiara Rosa, Valerie E Pye, Carl Graham, …, Laura E McCoy, Katie J Doores, Peter Cherepanov
- Sci Adv, 10.1126/sciadv.abg7607
The transition from normal lung anatomy to minimal and established fibrosis in idiopathic pulmonary fibrosis (IPF)
- Feng Xu, Naoya Tanabe, Dragos M Vasilescu, …, Christopher J Ryerson, Raymond T Ng, James C Hogg
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Preexisting and de novo humoral immunity to SARS-CoV-2 in humans
- Kevin W Ng, Nikhil Faulkner, Georgina H Cornish, …, Peter Cherepanov, Eleni Nastouli, George Kassiotis
- Science, 10.1126/science.abe1107
Tissue-specific and interferon-inducible expression of nonfunctional ACE2 through endogenous retroelement co-option
- Kevin W Ng, Jan Attig, William Bolland, …, Steve Gamblin, Andreas Wack, George Kassiotis
- Nat Genet, 10.1038/s41588-020-00732-8
Assessment of long non-coding RNA expression reveals novel mediators of the lung tumour immune response
- Adam P Sage, Kevin W Ng, Erin A Marshall, …, Carolyn J Brown, Ninan Abraham, Wan L Lam
- Sci Rep, 10.1038/s41598-020-73787-6
Pandemic peak SARS-CoV-2 infection and seroconversion rates in London frontline health-care workers
- Catherine F Houlihan, Nina Vora, Thomas Byrne, …, Charles Swanton, Andrew Hayward, Eleni Nastouli
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Epithelial tumor suppressor ELF3 is a lineage-specific amplified oncogene in lung adenocarcinoma
- Katey S S Enfield, Erin A Marshall, Christine Anderson, …, Aly Karsan, Igor Jurisica, Wan L Lam
- Nat Commun, 10.1038/s41467-019-13295-y
Soluble PD-L1 generated by endogenous retroelement exaptation is a receptor antagonist
- Kevin W Ng, Jan Attig, George R Young, …, Spyros I Papamichos, Ioannis Kotsianidis, George Kassiotis
- Elife, 10.7554/elife.50256
Discovery of Previously Undetected MicroRNAs in Mesothelioma and Their Use as Tissue-of-Origin Markers
- Victor D Martinez, Erin A Marshall, Christine Anderson, …, Katey S S Enfield, Zhaolin Xu, Wan L Lam
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