Genomic screening of 16 UK native bat species through conservationist networks uncovers coronaviruses with zoonotic potential
- Kelvin Lau
- June 27, 2023
- kedalionlabs.com
- Cedric C S Tan, Jahcub Trew, Thomas P Peacock, …, Lucy van Dorp, Francois Balloux, Vincent Savolainen
- Nat Commun, 10.1038/s41467-023-38717-w
High-affinity peptides developed against calprotectin and their application as synthetic ligands in diagnostic assays
- Kelvin Lau
- May 17, 2023
- kedalionlabs.com
- Cristina Díaz-Perlas, Benjamin Ricken, Lluc Farrera-Soler, …, Kelvin Lau, Christian-Benedikt Gerhold, Christian Heinis
- Nat Commun, 10.1038/s41467-023-38075-7
Machine learning predictions of MHC-II specificities reveal alternative binding mode of class II epitopes
- Kelvin Lau
- April 6, 2023
- kedalionlabs.com
- Julien Racle, Philippe Guillaume, Julien Schmidt, …, Michal Bassani-Sternberg, Alexandre Harari, David Gfeller
- Immunity, 10.1016/j.immuni.2023.03.009
Cryo-EM structures and binding of mouse and human ACE2 to SARS-CoV-2 variants of concern indicate that mutations enabling immune escape could expand host range
- Kelvin Lau
- April 5, 2023
- kedalionlabs.com
- Dongchun Ni, Priscilla Turelli, Bertrand Beckert, …, Didier Trono, Henning Stahlberg, Kelvin Lau
- PLoS Pathog, 10.1371/journal.ppat.1011206
Continuous population-level monitoring of SARS-CoV-2 seroprevalence in a large European metropolitan region
- Ioannis Xenarios
- Kelvin Lau
- January 9, 2023
- kedalionlabs.com
- Marc Emmenegger, Elena De Cecco, David Lamparter, …, Ioannis Xenarios, David I Stuart, Adriano Aguzzi
- None, 10.1016/j.isci.2023.105928
Patient-derived monoclonal antibody neutralizes SARS-CoV-2 Omicron variants and confers full protection in monkeys
- Kelvin Lau
- July 25, 2022
- kedalionlabs.com
- Craig Fenwick, Priscilla Turelli, Dongchun Ni, …, Roger LeGrand, Didier Trono, Giuseppe Pantaleo
- Nat Microbiol, 10.1038/s41564-022-01198-6
A highly potent antibody effective against SARS-CoV-2 variants of concern
- Kelvin Lau
- October 2, 2021
- kedalionlabs.com
- Craig Fenwick, Priscilla Turelli, Laurent Perez, …, Yves Lévy, Didier Trono, Giuseppe Pantaleo
- Cell Rep, 10.1016/j.celrep.2021.109814
A Nanoscaffolded Spike-RBD Vaccine Provides Protection against SARS-CoV-2 with Minimal Anti-Scaffold Response
- Kelvin Lau
- April 30, 2021
- kedalionlabs.com
- Duško Lainšček, Tina Fink, Vida Forstnerič, …, Alexander Herrmann, Andreas Pichlmair, Roman Jerala
- None, 10.3390/vaccines9050431
A constitutively monomeric UVR8 photoreceptor confers enhanced UV-B photomorphogenesis
- Kelvin Lau
- February 5, 2021
- kedalionlabs.com
- Roman Podolec, Kelvin Lau, Timothée B Wagnon, Michael Hothorn, Roman Ulm
- Proc Natl Acad Sci U S A, 10.1073/pnas.2017284118
Changes in SARS-CoV-2 Spike versus Nucleoprotein Antibody Responses Impact the Estimates of Infections in Population-Based Seroprevalence Studies
- Kelvin Lau
- November 4, 2020
- kedalionlabs.com
- Craig Fenwick, Antony Croxatto, Alix T Coste, …, Didier Trono, Gilbert Greub, Giuseppe Pantaleo
- J Virol, 10.1128/jvi.01828-20