CAMK2D serves as a molecular scaffold for RNF8-MAD2 complex to induce mitotic checkpoint in glioma
- You Heng Chuah, Emmy Xue Yun Tay, Oleg V Grinchuk, …, Chandra Shekhar Verma, Zhewang Lin, Derrick Sek Tong Ong
- Cell Death Differ, 10.1038/s41418-023-01192-3
Glial cells expressing visual cycle genes are vital for photoreceptor survival in the zebrafish pineal gland
- Yotam Elazary, Kathleen Cheow, Ruey-Kuang Cheng, …, Karen Crasta, Yoav Gothilf, Suresh J Jesuthasan
- J Pineal Res, 10.1111/jpi.12854
Assessment of cell cycle regulators in human peripheral blood cells as markers of cellular senescence
- Lihuan Guan, Karen C Crasta, Andrea B Maier
- Ageing Res Rev, 10.1016/j.arr.2022.101634
PLK1 inhibition selectively induces apoptosis in ARID1A deficient cells through uncoupling of oxygen consumption from ATP production
- Upadhyayula S Srinivas, Norbert S C Tay, Patrick Jaynes, …, Wai Leong Tam, Christian Frezza, Anand D Jeyasekharan
- Oncogene, 10.1038/s41388-022-02219-8
E2F and STAT3 provide transcriptional synergy for histone variant H2AZ activation to sustain glioblastoma chromatin accessibility and tumorigenicity
- Jeehyun Yoon, Oleg V Grinchuk, Roberto Tirado-Magallanes, …, Chin Tong Ong, Touati Benoukraf, Derrick Sek Tong Ong
- Cell Death Differ, 10.1038/s41418-021-00926-5
Breaking the vicious circle: Extrachromosomal circular DNA as an emerging player in tumour evolution
- Matius Robert, Karen Crasta
- Semin Cell Dev Biol, 10.1016/j.semcdb.2021.11.015
Exosomes as Emerging Pro-Tumorigenic Mediators of the Senescence-Associated Secretory Phenotype
- Rekha Jakhar, Karen Crasta
- Int J Mol Sci, 10.3390/ijms20102547
Lipid accumulation facilitates mitotic slippage-induced adaptation to anti-mitotic drug treatment
- Alex Wong, Sixun Chen, Lay Kien Yang, Yoganathan Kanagasundaram, Karen Crasta
- Cell Death Dis, 10.1038/s41420-018-0127-5
Mutational game changer: Chromothripsis and its emerging relevance to cancer
- Monique Nicole Helena Luijten, Jeannie Xue Ting Lee, Karen Carmelina Crasta
- Mutat Res, 10.1016/j.mrrev.2018.06.004
Dropping in on lipid droplets: insights into cellular stress and cancer
- Peter Shyu, Xing Fah Alex Wong, Karen Crasta, Guillaume Thibault
- Biosci Rep, 10.1042/bsr20180764
Generation of Micronuclei and Detection of Chromosome Pulverization
- Monique N H Luijten, Jeannie X T Lee, Sixun Chen, Karen C Crasta
- Methods Mol Biol, 10.1007/978-1-4939-7780-2_12
Consequences of mitotic slippage for antimicrotubule drug therapy
- Bing Cheng, Karen Crasta
- Endocr Relat Cancer, 10.1530/erc-17-0147