Scholar: Juan Carlos García-Cañaveras

Juan Carlos García-Cañaveras

Academic lineage

FAMetA: a mass isotopologue-based tool for the comprehensive analysis of fatty acid metabolism

  • María I Alcoriza-Balaguer, Juan C García-Cañaveras, Marta Benet, …, Marta Benet, Oscar Juan-Vidal, Agustín Lahoz
  • Brief Bioinform, 10.1093/bib/bbad064
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LipidMS 3.0: an R-package and a web-based tool for LC-MS/MS data processing and lipid annotation

  • María Isabel Alcoriza-Balaguer, Juan Carlos García-Cañaveras, Francisco Javier Ripoll-Esteve, …, Francisco Javier Ripoll-Esteve, Marta Roca, Agustín Lahoz
  • Bioinformatics, 10.1093/bioinformatics/btac581
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MTHFD2 is a metabolic checkpoint controlling effector and regulatory T cell fate and function

  • Ayaka Sugiura, Gabriela Andrejeva, Kelsey Voss, …, Ashutosh K Mangalam, Joshua D Rabinowitz, Jeffrey C Rathmell
  • Immunity, 10.1016/j.immuni.2021.10.011
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CAR T-Cells Depend on the Coupling of NADH Oxidation with ATP Production

  • Juan C Garcia-Canaveras, David Heo, Sophie Trefely, …, Carl H June, Joshua D Rabinowitz, Roddy S O’Connor
  • Cells, 10.3390/cells10092334
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Reviewing the metabolome coverage provided by LC-MS: Focus on sample preparation and chromatography-A tutorial

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Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity

  • Alison E Ringel, Jefte M Drijvers, Gregory J Baker, …, Joshua D Rabinowitz, Arlene H Sharpe, Marcia C Haigis
  • Cell, 10.1016/j.cell.2020.11.009
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Enhancing Chimeric Antigen Receptor T Cell Anti-tumor Function through Advanced Media Design

  • Saba Ghassemi, Francisco J Martinez-Becerra, Alyssa M Master, …, Michael C Milone, Carl H June, Roddy S O’Connor
  • None, 10.1016/j.omtm.2020.07.008
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Chaperone-mediated autophagy regulates the pluripotency of embryonic stem cells

  • Yi Xu, Yang Zhang, Juan C García-Cañaveras, …, Ian A Blair, Joshua D Rabinowitz, Xiaolu Yang
  • Science, 10.1126/science.abb4467
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A small molecule G6PD inhibitor reveals immune dependence on pentose phosphate pathway

  • Jonathan M Ghergurovich, Juan C García-Cañaveras, Joshua Wang, …, Ulf H Beier, Hahn Kim, Joshua D Rabinowitz
  • Nat Chem Biol, 10.1038/s41589-020-0533-x
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SHMT inhibition is effective and synergizes with methotrexate in T-cell acute lymphoblastic leukemia

  • Juan C García-Cañaveras, Olga Lancho, Gregory S Ducker, …, Hahn Kim, Daniel Herranz, Joshua D Rabinowitz
  • Leukemia, 10.1038/s41375-020-0845-6
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Serine Catabolism Feeds NADH when Respiration Is Impaired

  • Lifeng Yang, Juan Carlos Garcia Canaveras, Zihong Chen, …, Eileen White, Raphael J Morscher, Joshua D Rabinowitz
  • Cell Metab, 10.1016/j.cmet.2020.02.017
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Lactate dehydrogenase inhibition synergizes with IL-21 to promote CD8 + T cell stemness and antitumor immunity

  • Dalton Hermans, Sanjivan Gautam, Juan C García-Cañaveras, …, Joshua D Rabinowitz, Luca Gattinoni, Warren J Leonard
  • Proc Natl Acad Sci U S A, 10.1073/pnas.1920413117
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Author Correction: Distinct modes of mitochondrial metabolism uncouple T cell differentiation and function

  • Will Bailis, Justin A Shyer, Jun Zhao, …, Joshua Rabinowitz, Joe Craft, Richard A Flavell
  • Nature, 10.1038/s41586-019-1490-y
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The Tumor Metabolic Microenvironment: Lessons from Lactate

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