Spatially resolved characterization of tissue metabolic compartments in fasted and high-fat diet livers
- Sylwia A Stopka, Jiska van der Reest, Walid M Abdelmoula, …, Alison E Ringel, Marcia C Haigis, Nathalie Y R Agar
- PLoS One, 10.1371/journal.pone.0261803
Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity
- Alison E Ringel, Jefte M Drijvers, Gregory J Baker, …, Joshua D Rabinowitz, Arlene H Sharpe, Marcia C Haigis
- Cell, 10.1016/j.cell.2020.11.009
Pharmacologic Screening Identifies Metabolic Vulnerabilities of CD8 + T Cells
- Jefte M Drijvers, Jacob E Gillis, Tara Muijlwijk, …, Justin D Trombley, Marcia C Haigis, Arlene H Sharpe
- Cancer Immunol Res, 10.1158/2326-6066.cir-20-0384
Adaptation of Human iPSC-Derived Cardiomyocytes to Tyrosine Kinase Inhibitors Reduces Acute Cardiotoxicity via Metabolic Reprogramming
- Huan Wang, Robert P Sheehan, Adam C Palmer, …, Laura Maliszewski, Marcia C Haigis, Peter K Sorger
- Cell Syst, 10.1016/j.cels.2019.03.009
Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate
- Abhishek A Chakraborty, Tuomas Laukka, Matti Myllykoski, …, Sabina Signoretti, Peppi Koivunen, William G Kaelin
- Science, 10.1126/science.aaw1026
Chemical and Physiological Features of Mitochondrial Acylation
- Alison E Ringel, Sarah A Tucker, Marcia C Haigis
- Mol Cell, 10.1016/j.molcel.2018.10.023
Small-Molecule Screen Identifies De Novo Nucleotide Synthesis as a Vulnerability of Cells Lacking SIRT3
- Karina N Gonzalez Herrera, Elma Zaganjor, Yoshinori Ishikawa, …, Peter K Sorger, Clary B Clish, Marcia C Haigis
- Cell Rep, 10.1016/j.celrep.2018.01.076