Comparative Evaluation of Synthetic Cytokines for Enhancing Production and Performance of NK92 Cell-Based Therapies
- Simrita Deol, Patrick S Donahue, Roxana E Mitrut, …, Jihae Ahn, Bin Zhang, Joshua N Leonard
- None, 10.1089/genbio.2023.0024
The sound of silence: Transgene silencing in mammalian cell engineering
- Alan Cabera, Hailey I Edelstein, Fokion Glykofrydis, …, Lacramioara Bintu, Kate E Galloway, Tara L Deans
- Cell Syst, 10.1016/j.cels.2022.11.005
Mapping CAR T-Cell Design Space Using Agent-Based Models
- Alexis N Prybutok, Jessica S Yu, Joshua N Leonard, Neda Bagheri
- None, 10.3389/fmolb.2022.849363
Fighting fire with fire: deploying complexity in computational modeling to effectively characterize complex biological systems
- Alexis N Prybutok, Jason Y Cain, Joshua N Leonard, Neda Bagheri
- Curr Opin Biotechnol, 10.1016/j.copbio.2022.102704
The evolution of synthetic receptor systems
- Janvie Manhas, Hailey I Edelstein, Janvie Manhas, Hailey I Edelstein, Joshua N Leonard, Leonardo Morsut
- Nat Chem Biol, 10.1038/s41589-021-00926-z
Control of mammalian cell-based devices with genetic programming
- Kate E Dray, Hailey I Edelstein, Kathleen S Dreyer, Joshua N Leonard
- None, 10.1016/j.coisb.2021.100372
RNA Sequence and Structure Determinants of Pol III Transcriptional Termination in Human Cells
- Matthew S Verosloff, William K Corcoran, Taylor B Dolberg, David Z Bushhouse, Joshua N Leonard, Julius B Lucks
- J Mol Biol, 10.1016/j.jmb.2021.166978
Model-guided design of mammalian genetic programs
- J J Muldoon, V Kandula, M Hong, …, J D Boucher, N Bagheri, J N Leonard
- Sci Adv, 10.1126/sciadv.abe9375
Computation-guided optimization of split protein systems
- Taylor B Dolberg, Anthony T Meger, Jonathan D Boucher, …, Alexis N Prybutok, Srivatsan Raman, Joshua N Leonard
- Nat Chem Biol, 10.1038/s41589-020-00729-8