Academic lineage
Structural basis for species-selective targeting of Hsp90 in a pathogenic fungus
- Luke Whitesell, Nicole Robbins, David S Huang, …, Lauren E Brown, Juan Pizarro, Leah E Cowen
- Nat Commun, 10.1038/s41467-018-08248-w
Functional divergence of a global regulatory complex governing fungal filamentation
- Elizabeth J Polvi, Amanda O Veri, Zhongle Liu, …, Anne-Claude Gingras, Anna Selmecki, Leah E Cowen
- PLoS Genet, 10.1371/journal.pgen.1007901
Mutations, protein homeostasis, and epigenetic control of genome integrity
- Jinglin Lucy Xie, Daniel F Jarosz
- DNA Repair (Amst), 10.1016/j.dnarep.2018.08.004
Functional Genomic Screening Reveals Core Modulators of Echinocandin Stress Responses in Candida albicans
- Tavia Caplan, Elizabeth J Polvi, Jinglin L Xie, …, Michelle D Leach, Nicole Robbins, Leah E Cowen
- Cell Rep, 10.1016/j.celrep.2018.04.084
Ydj1 governs fungal morphogenesis and stress response, and facilitates mitochondrial protein import via Mas1 and Mas2
- Jinglin L Xie, Iryna Bohovych, Erin O Y Wong, …, Oleh Khalimonchuk, Leah E Cowen, Michelle D Leach
- None, 10.15698/mic2017.10.594
The Candida albicans transcription factor Cas5 couples stress responses, drug resistance and cell cycle regulation
- Jinglin L Xie, Longguang Qin, Zhengqiang Miao, …, Koon Ho Wong, Nicole Robbins, Leah E Cowen
- Nat Commun, 10.1038/s41467-017-00547-y
Staurosporine Induces Filamentation in the Human Fungal Pathogen Candida albicans via Signaling through Cyr1 and Protein Kinase A
- Jinglin L Xie, Teresa R O’Meara, Elizabeth J Polvi, Nicole Robbins, Leah E Cowen
- mSphere, 10.1128/msphere.00056-17
Functional Genomic Analysis of Candida albicans Adherence Reveals a Key Role for the Arp2/3 Complex in Cell Wall Remodelling and Biofilm Formation
- Jason A Lee, Nicole Robbins, Jinglin L Xie, Troy Ketela, Leah E Cowen
- PLoS Genet, 10.1371/journal.pgen.1006452
Signaling through Lrg1, Rho1 and Pkc1 Governs Candida albicans Morphogenesis in Response to Diverse Cues
- Jinglin L Xie, Nora Grahl, Trevor Sless, …, Deborah A Hogan, Nicole Robbins, Leah E Cowen
- PLoS Genet, 10.1371/journal.pgen.1006405
Elucidating drug resistance in human fungal pathogens
- Jinglin Lucy Xie, Elizabeth J Polvi, Tanvi Shekhar-Guturja, Leah E Cowen
- Future Microbiol, 10.2217/fmb.14.18
Global analysis of the evolution and mechanism of echinocandin resistance in Candida glabrata
- Sheena D Singh-Babak, Tomas Babak, Stephanie Diezmann, …, Robert P Rennie, Joseph Heitman, Leah E Cowen
- PLoS Pathog, 10.1371/journal.ppat.1002718
PoxA, yjeK, and elongation factor P coordinately modulate virulence and drug resistance in Salmonella enterica
- William Wiley Navarre, S Betty Zou, Hervé Roy, …, Runjun Kumar, Michael Ibba, Ferric C Fang
- Mol Cell, 10.1016/j.molcel.2010.06.021