Scholar: Jing Hou

Jing Hou

Academic lineage

The proteomic landscape of genome-wide genetic perturbations

  • Christoph B Messner, Vadim Demichev, Julia Muenzner, …, Charles Boone, Georg Kustatscher, Markus Ralser
  • Cell, 10.1016/j.cell.2023.03.026
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Loss-of-function mutation survey revealed that genes with background-dependent fitness are rare and functionally related in yeast

  • Elodie Caudal, Anne Friedrich, Arthur Jallet, Marion Garin, Jing Hou, Joseph Schacherer
  • Proc Natl Acad Sci U S A, 10.1073/pnas.2204206119
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Leveraging machine learning essentiality predictions and chemogenomic interactions to identify antifungal targets

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Environmental robustness of the global yeast genetic interaction network

  • Michael Costanzo, Jing Hou, Vincent Messier, …, Chad L Myers, Charles Boone, Brenda Andrews
  • Science, 10.1126/science.abf8424
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Systematic analysis of bypass suppression of essential genes

  • Jolanda van Leeuwen, Carles Pons, Guihong Tan, …, Patrick Aloy, Brenda J Andrews, Charles Boone
  • Mol Syst Biol, 10.15252/msb.20209828
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Extensive impact of low-frequency variants on the phenotypic landscape at population-scale

  • Téo Fournier, Omar Abou Saada, Jing Hou, Jackson Peter, Elodie Caudal, Joseph Schacherer
  • Elife, 10.7554/elife.49258
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Complex modifier landscape underlying genetic background effects

  • Jing Hou, Guihong Tan, Gerald R Fink, Brenda J Andrews, Charles Boone
  • Proc Natl Acad Sci U S A, 10.1073/pnas.1820915116
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Genetic Network Complexity Shapes Background-Dependent Phenotypic Expression

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Variation of the meiotic recombination landscape and properties over a broad evolutionary distance in yeasts

  • Christian Brion, Sylvain Legrand, Jackson Peter, …, Anne Friedrich, Bertrand Llorente, Joseph Schacherer
  • PLoS Genet, 10.1371/journal.pgen.1006917
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Fitness Trade-Offs Lead to Suppressor Tolerance in Yeast

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The Hidden Complexity of Mendelian Traits across Natural Yeast Populations

  • Jing Hou, Anastasie Sigwalt, Téo Fournier, …, Jacky de Montigny, Maitreya J Dunham, Joseph Schacherer
  • Cell Rep, 10.1016/j.celrep.2016.06.048
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Dissection of quantitative traits by bulk segregant mapping in a protoploid yeast species

  • Anastasie Sigwalt, Claudia Caradec, Christian Brion, …, Bertrand Llorente, Anne Friedrich, Joseph Schacherer
  • FEMS Yeast Res, 10.1093/femsyr/fow056
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Species-wide survey reveals the various flavors of intraspecific reproductive isolation in yeast

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Negative epistasis: a route to intraspecific reproductive isolation in yeast?

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Comprehensive survey of condition-specific reproductive isolation reveals genetic incompatibility in yeast

  • Jing Hou, Anne Friedrich, Jean-Sebastien Gounot, Joseph Schacherer
  • Nat Commun, 10.1038/ncomms8214
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Population genomic analysis reveals highly conserved mitochondrial genomes in the yeast species Lachancea thermotolerans

  • Kelle C Freel, Anne Friedrich, Jing Hou, Joseph Schacherer
  • Genome Biol Evol, 10.1093/gbe/evu203
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Chromosomal rearrangements as a major mechanism in the onset of reproductive isolation in Saccharomyces cerevisiae

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Comparative mitochondrial genomics within and among yeast species of the Lachancea genus

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