Scholar: Jean Beggs

Jean Beggs

Blocking late stages of splicing quickly limits pre-spliceosome assembly in vivo

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Extremely Rapid and Specific Metabolic Labelling of RNA In Vivo with 4-Thiouracil (Ers4tU)

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Tuning Degradation to Achieve Specific and Efficient Protein Depletion

  • J David Barrass, Gonzalo I Mendoza-Ochoa, Isabella E Maudlin, Emanuela Sani, Jean D Beggs
  • J Vis Exp, 10.3791/59874
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A Nuclear Export Block Triggers the Decay of Newly Synthesized Polyadenylated RNA

  • Agnieszka Tudek, Manfred Schmid, Marius Makaras, J David Barrass, Jean D Beggs, Torben Heick Jensen
  • Cell Rep, 10.1016/j.celrep.2018.07.103
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Transcription rate strongly affects splicing fidelity and cotranscriptionality in budding yeast

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RNA polymerase II stalling at pre-mRNA splice sites is enforced by ubiquitination of the catalytic subunit

  • Laura Milligan, Camille Sayou, Alex Tuck, …, Jean D Beggs, Grzegorz Kudla, David Tollervey
  • Elife, 10.7554/elife.27082
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Transcriptome-wide RNA processing kinetics revealed using extremely short 4tU labeling

  • J David Barrass, Jane E A Reid, Yuanhua Huang, …, Guido Sanguinetti, Jean D Beggs, Sander Granneman
  • Genome Biol, 10.1186/s13059-015-0848-1
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