Pyruvate metabolism controls chromatin remodeling during CD4 + TÂ cell activation
- Jared Rutter
- June 2, 2023
- kedalionlabs.com
- Enric Mocholi, Laura Russo, Keshav Gopal, …, John Ussher, Boudewijn M T Burgering, Paul J Coffer
- Cell Rep, 10.1016/j.celrep.2023.112583
The secret life of lactate: A novel cell-cycle regulatory mechanism
- Jared Rutter
- May 3, 2023
- kedalionlabs.com
- Ahmad A Cluntun, Jared Rutter, Ahmad A Cluntun, Jared Rutter, Ahmad A Cluntun, Jared Rutter
- Cell Metab, 10.1016/j.cmet.2023.04.006
Metaboverse enables automated discovery and visualization of diverse metabolic regulatory patterns
- Jared Rutter
- Jordan A Berg
- April 3, 2023
- kedalionlabs.com
- Youjia Zhou, Yeyun Ouyang, Ahmad A Cluntun, …, James E Cox, Bei Wang, Jared Rutter
- Nat Cell Biol, 10.1038/s41556-023-01117-9
Protein-metabolite interactomics of carbohydrate metabolism reveal regulation of lactate dehydrogenase
- Jared Rutter
- Jordan A Berg
- Sean R Hackett
- March 9, 2023
- kedalionlabs.com
- Kevin G Hicks, Ahmad A Cluntun, Heidi L Schubert, …, Florian L Muller, James E Cox, Jared Rutter
- Science, 10.1126/science.abm3452
Recessive pathogenic variants in MCAT cause combined oxidative phosphorylation deficiency
- Jared Rutter
- March 7, 2023
- kedalionlabs.com
- Bryn D Webb, Sara M Nowinski, Ashley Solmonson, …, Ralph J DeBerardinis, Jared Rutter, Sander M Houten
- Elife, 10.7554/elife.68047
Transferred mitochondria accumulate reactive oxygen species, promoting proliferation
- Jared Rutter
- March 6, 2023
- kedalionlabs.com
- Chelsea U Kidwell, Joseph R Casalini, Soorya Pradeep, …, Alana L Welm, Thomas A Zangle, Minna Roh-Johnson
- Elife, 10.7554/elife.85494
On the cutting edge: perspectives in bioenergetics
- Jared Rutter
- Shingo Kajimura
- March 3, 2023
- kedalionlabs.com
- Anna Krook, Jared Rutter, Anna Krook, …, Anna Krook, Jared Rutter, Shingo Kajimura
- Nat Rev Endocrinol, 10.1038/s41574-023-00820-9
Mitochondrial phosphatidylethanolamine modulates UCP1 to promote brown adipose thermogenesis
- Claudio J Villanueva
- Jared Rutter
- February 24, 2023
- kedalionlabs.com
- Jordan M Johnson, Alek D Peterlin, Enrique Balderas, …, Dipayan Chaudhuri, Zachary Gerhart-Hines, Katsuhiko Funai
- Sci Adv, 10.1126/sciadv.ade7864
Collateral deletion of the mitochondrial AAA+ ATPase ATAD1 sensitizes cancer cells to proteasome dysfunction
- Corey N Cunningham
- David M Sabatini
- Jared Rutter
- Jordan A Berg
- November 21, 2022
- kedalionlabs.com
- Jacob M Winter, Heidi L Fresenius, Corey N Cunningham, …, David M Sabatini, Matthew L Wohlever, Jared Rutter
- Elife, 10.7554/elife.82860
Intramuscular administration of glyoxylate rescues swine from lethal cyanide poisoning and ameliorates the biochemical sequalae of cyanide intoxication
- Jared Rutter
- November 3, 2022
- kedalionlabs.com
- Vik S Bebarta, Xu Shi, Shunning Zheng, …, Jared Rutter, Robert E Gerszten, Anjali K Nath
- Toxicol Sci, 10.1093/toxsci/kfac116
Stressed to death: Mitochondrial stress responses connect respiration and apoptosis in cancer
- Jared Rutter
- August 12, 2022
- kedalionlabs.com
- Jacob M Winter, Tarun Yadav, Jared Rutter
- Mol Cell, 10.1016/j.molcel.2022.07.012
Microglia Drive Pockets of Neuroinflammation in Middle Age
- Daniel R Saban
- Jared Rutter
- April 9, 2022
- kedalionlabs.com
- Eric N Moca, Daniela Lecca, Keenan T Hope, …, Daniel R Saban, Nigel H Greig, Lindsay M De Biase
- J Neurosci, 10.1523/jneurosci.1922-21.2022
Glyoxylate protects against cyanide toxicity through metabolic modulation
- Jared Rutter
- March 24, 2022
- kedalionlabs.com
- Jason R Nielson, Anjali K Nath, Kim P Doane, …, Matthew Brenner, Robert E Gerszten, Randall T Peterson
- Sci Rep, 10.1038/s41598-022-08803-y
Paradoxical neuronal hyperexcitability in a mouse model of mitochondrial pyruvate import deficiency
- Jared Rutter
- February 21, 2022
- kedalionlabs.com
- Andres De La Rossa, Marine H Laporte, Simone Astori, …, Michael R Duchen, Carmen Sandi, Jean-Claude Martinou
- Elife, 10.7554/elife.72595