
Academic lineage
- Bernhard Ø Palsson - Ph.D. student
Systems biology elucidates the distinctive metabolic niche filled by the human gut microbe Eggerthella lenta
- Almut Heinken
- Ines Thiele
- Peter J Turnbaugh
- May 19, 2023
- kedalionlabs.com
- Cecilia Noecker, Juan Sanchez, Jordan E Bisanz, …, Ines Thiele, Brian C DeFelice, Peter J Turnbaugh
- PLoS Biol, 10.1371/journal.pbio.3002125
A nutrition algorithm to optimize feed and medium composition using genome-scale metabolic models
- Ines Thiele
- February 1, 2023
- kedalionlabs.com
- Bronson R Weston, Ines Thiele, Bronson R Weston, …, Ines Thiele, Bronson R Weston, Ines Thiele
- Metab Eng, 10.1016/j.ymben.2023.01.010
Genome-scale metabolic reconstruction of 7,302 human microorganisms for personalized medicine
- Almut Heinken, Johannes Hertel, Geeta Acharya, …, Christopher S Henry, Ronan M T Fleming, Ines Thiele
- Nat Biotechnol, 10.1038/s41587-022-01628-0
MetaboAnnotator: an efficient toolbox to annotate metabolites in genome-scale metabolic reconstructions
- Ines Thiele
- Ronan M T Fleming
- September 1, 2022
- kedalionlabs.com
- Ines Thiele, German Preciat, Ronan M T Fleming
- Bioinformatics, 10.1093/bioinformatics/btac596
The gut microbial metabolite formate exacerbates colorectal cancer progression
- Almut Heinken
- Ines Thiele
- Thomas Sauter
- April 19, 2022
- kedalionlabs.com
- Dominik Ternes, Mina Tsenkova, Vitaly Igorevich Pozdeev, …, Serge Haan, Paul Wilmes, Elisabeth Letellier
- Nat Metab, 10.1038/s42255-022-00558-0
Microbiome Modelling Toolbox 2.0: Efficient, tractable modelling of microbiome communities
- Almut Heinken
- Ines Thiele
- February 14, 2022
- kedalionlabs.com
- Almut Heinken, Ines Thiele, Almut Heinken, …, Ines Thiele, Almut Heinken, Ines Thiele
- Bioinformatics, 10.1093/bioinformatics/btac082
Early-Life Adversity Leaves Its Imprint on the Oral Microbiome for More Than 20 Years and Is Associated with Long-Term Immune Changes
- Ines Thiele
- December 10, 2021
- kedalionlabs.com
- Eleftheria G Charalambous, Sophie B MĂ©riaux, Pauline Guebels, …, Ines Thiele, Johannes Hertel, Jonathan D Turner
- Int J Mol Sci, 10.3390/ijms222312682
Author Correction: Rare genetic variants affecting urine metabolite levels link population variation to inborn errors of metabolism
- Ines Thiele
- October 7, 2021
- kedalionlabs.com
- Yurong Cheng, Pascal Schlosser, Johannes Hertel, …, Ines Thiele, Yong Li, Anna Köttgen
- Nat Commun, 10.1038/s41467-021-26242-7
Integration of a physiologically-based pharmacokinetic model with a whole-body, organ-resolved genome-scale model for characterization of ethanol and acetaldehyde metabolism
- Ines Thiele
- August 5, 2021
- kedalionlabs.com
- Leo Zhu, William Pei, Ines Thiele, …, William Pei, Ines Thiele, Radhakrishnan Mahadevan
- PLoS Comput Biol, 10.1371/journal.pcbi.1009110
Methanogenic granule growth and development is a continual process characterized by distinct morphological features
- Ines Thiele
- March 5, 2021
- kedalionlabs.com
- Simon Mills, Anna Christine Trego, John Ward, …, Piet N L Lens, Umer Zeeshan Ijaz, Gavin Collins
- J Environ Manage, 10.1016/j.jenvman.2021.112229
An international classification of inherited metabolic disorders (ICIMD)
- Ines Thiele
- December 19, 2020
- kedalionlabs.com
- Carlos R Ferreira, Shamima Rahman, Markus Keller, Johannes Zschocke
- J Inherit Metab Dis, 10.1002/jimd.12348
Arterio-venous metabolomics exploration reveals major changes across liver and intestine in the obese Yucatan minipig
- Ines Thiele
- August 31, 2019
- kedalionlabs.com
- Nathalie Poupin, Marie Tremblay-Franco, AurĂ©lien Amiel, …, Fabien Jourdan, Isabelle Savary-Auzeloux, Sergio Polakof
- Sci Rep, 10.1038/s41598-019-48997-2
Comparative Genomic Analysis Reveals Novel Microcompartment-Associated Metabolic Pathways in the Human Gut Microbiome
- Ines Thiele
- July 24, 2019
- kedalionlabs.com
- Dmitry A Ravcheev, Lubin Moussu, Semra Smajic, Ines Thiele
- None, 10.3389/fgene.2019.00636
Predicting gastrointestinal drug effects using contextualized metabolic models
- Ines Thiele
- June 27, 2019
- kedalionlabs.com
- Marouen Ben Guebila, Ines Thiele, Marouen Ben Guebila, Ines Thiele
- PLoS Comput Biol, 10.1371/journal.pcbi.1007100
Dynamic genome-scale cell-specific metabolic models reveal novel inter-cellular and intra-cellular metabolic communications during ovarian follicle development
- Ines Thiele
- June 12, 2019
- kedalionlabs.com
- Beatriz Peñalver BernabĂ©, Ines Thiele, Eugene Galdones, …, Teresa K Woodruff, Linda J Broadbelt, Lonnie D Shea
- BMC Bioinformatics, 10.1186/s12859-019-2825-2
Integrated In Vitro and In Silico Modeling Delineates the Molecular Effects of a Synbiotic Regimen on Colorectal-Cancer-Derived Cells
- Ines Thiele
- May 3, 2019
- kedalionlabs.com
- Kacy Greenhalgh, Javier Ramiro-Garcia, Almut Heinken, …, Serge Haan, Elisabeth Letellier, Paul Wilmes
- Cell Rep, 10.1016/j.celrep.2019.04.001
From Network Analysis to Functional Metabolic Modeling of the Human Gut Microbiota
- Ines Thiele
- March 31, 2018
- kedalionlabs.com
- Eugen Bauer, Ines Thiele
- mSystems, 10.1128/msystems.00209-17