Proteomic analysis for the effects of non-saponin fraction with rich polysaccharide from Korean Red Ginseng on Alzheimer’s disease in a mouse model
- Sujin Kim, Yunkwon Nam, Min-Jeong Kim, …, Yong Yook Lee, Hak Su Kim, Minho Moon
- None, 10.1016/j.jgr.2022.09.008
Computational prediction of interactions between Paxlovid and prescription drugs
- Yeji Kim, Jae Yong Ryu, Hyun Uk Kim, …, Jae Yong Ryu, Hyun Uk Kim, Sang Yup Lee
- Proc Natl Acad Sci U S A, 10.1073/pnas.2221857120
Recent development of machine learning models for the prediction of drug-drug interactions
- Eujin Hong, Junhyeok Jeon, Hyun Uk Kim, Eujin Hong, Junhyeok Jeon, Hyun Uk Kim
- None, 10.1007/s11814-023-1377-3
Machine learning-guided evaluation of extraction and simulation methods for cancer patient-specific metabolic models
- Sang Mi Lee, GaRyoung Lee, Hyun Uk Kim
- None, 10.1016/j.csbj.2022.06.027
Comparative genomic analysis of Streptomyces rapamycinicus NRRL 5491 and its mutant overproducing rapamycin
- Hee-Geun Jo, Joshua Julio Adidjaja, Do-Kyung Kim, …, Byung-Kwan Cho, Hyun Uk Kim, Min-Kyu Oh
- Sci Rep, 10.1038/s41598-022-14199-6
Systems metabolic engineering of Streptomyces venezuelae for the enhanced production of pikromycin
- Min Kyung Cho, Byung Tae Lee, Hyun Uk Kim, Min-Kyu Oh
- Biotechnol Bioeng, 10.1002/bit.28114
Efficient Production of Naringin Acetate with Different Acyl Donors via Enzymatic Transesterification by Lipases
- Yesol Baek, Seungmee Lee, Jemin Son, …, Si Jae Park, Hah Young Yoo, Chulhwan Park
- Int J Environ Res Public Health, 10.3390/ijerph19052972
Predicting Dynamic Clinical Outcomes of the Chemotherapy for Canine Lymphoma Patients Using a Machine Learning Model
- Jamin Koo, Kyucheol Choi, Peter Lee, …, Mary Ocnean, Hyun Uk Kim, Sungwon Lim
- None, 10.3390/vetsci8120301
Omics and Computational Modeling Approaches for the Effective Treatment of Drug-Resistant Cancer Cells
- Hae Deok Jung, Yoo Jin Sung, Hyun Uk Kim
- None, 10.3389/fgene.2021.742902
Predicting biochemical and physiological effects of natural products from molecular structures using machine learning
- Junhyeok Jeon, Seongmo Kang, Hyun Uk Kim
- Nat Prod Rep, 10.1039/d1np00016k
Systems and synthetic biology to elucidate secondary metabolite biosynthetic gene clusters encoded in Streptomyces genomes
- Namil Lee, Soonkyu Hwang, Woori Kim, …, Min-Kyu Oh, Bernhard O Palsson, Byung-Kwan Cho
- Nat Prod Rep, 10.1039/d0np00071j
Modeling regulatory networks using machine learning for systems metabolic engineering
- Mun Su Kwon, Byung Tae Lee, Sang Yup Lee, Hyun Uk Kim
- Curr Opin Biotechnol, 10.1016/j.copbio.2020.02.014
Current status of pan-genome analysis for pathogenic bacteria
- Yeji Kim, Changdai Gu, Hyun Uk Kim, Sang Yup Lee
- Curr Opin Biotechnol, 10.1016/j.copbio.2019.12.001
Machine learning applications in systems metabolic engineering
- Gi Bae Kim, Won Jun Kim, Hyun Uk Kim, Sang Yup Lee
- Curr Opin Biotechnol, 10.1016/j.copbio.2019.08.010
Deep learning enables high-quality and high-throughput prediction of enzyme commission numbers
- Jae Yong Ryu, Hyun Uk Kim, Sang Yup Lee
- Proc Natl Acad Sci U S A, 10.1073/pnas.1821905116
Metabolic engineering of Corynebacterium glutamicum for the production of glutaric acid, a C5 dicarboxylic acid platform chemical
- Hee Taek Kim, Tae Uk Khang, Kei-Anne Baritugo, …, Sang Yup Lee, Si Jae Park, Jeong Chan Joo
- Metab Eng, 10.1016/j.ymben.2018.08.007
Recent development of computational resources for new antibiotics discovery
- Hyun Uk Kim, Kai Blin, Sang Yup Lee, Tilmann Weber
- Curr Opin Microbiol, 10.1016/j.mib.2017.10.027
Recent development of antiSMASH and other computational approaches to mine secondary metabolite biosynthetic gene clusters
- Kai Blin, Hyun Uk Kim, Marnix H Medema, Tilmann Weber
- Brief Bioinform, 10.1093/bib/bbx146
Toward Systems Metabolic Engineering of Streptomycetes for Secondary Metabolites Production
- Helene Lunde Robertsen, Tilmann Weber, Hyun Uk Kim, Sang Yup Lee
- Biotechnol J, 10.1002/biot.201700465