Scholar: Gina M Denicola

Gina M Denicola

Retraction Notice to: mTORC1-Induced HK1-Dependent Glycolysis Regulates NLRP3 Inflammasome Activation

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Quantification and Tracing of Stable Isotope into Cysteine and Glutathione

  • Yun Pyo Kang, Gina M DeNicola, Yun Pyo Kang, Gina M DeNicola, Yun Pyo Kang, Gina M DeNicola
  • Methods Mol Biol, 10.1007/978-1-0716-3247-5_5
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Distinct Nrf2 Signaling Thresholds Mediate Lung Tumor Initiation and Progression

  • Janine M DeBlasi, Aimee Falzone, Samantha Caldwell, …, Iok In Christine Chio, Florian A Karreth, Gina M DeNicola
  • Cancer Res, 10.1158/0008-5472.can-22-3848
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Source of nicotinamide governs its metabolic fate in cultured cells, mice, and humans

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Comprehensive Metabolic Tracing Reveals the Origin and Catabolism of Cysteine in Mammalian Tissues and Tumors

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NADK-mediated de novo NADP(H) synthesis is a metabolic adaptation essential for breast cancer metastasis

  • Didem Ilter, Stanislav Drapela, Tanya Schild, …, Gina M DeNicola, Melanie R McReynolds, Ana P Gomes
  • Redox Biol, 10.1016/j.redox.2023.102627
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Oxidation state-specific fluorescent copper sensors reveal oncogene-driven redox changes that regulate labile copper(II) pools

  • Aidan T Pezacki, Carson D Matier, Xingxing Gu, …, Timothy A Su, Donita C Brady, Christopher J Chang
  • Proc Natl Acad Sci U S A, 10.1073/pnas.2202736119
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Long-sought mediator of vitamin K recycling discovered

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A CRISPR screen identifies redox vulnerabilities for KEAP1/NRF2 mutant non-small cell lung cancer

  • Chang Jiang, Nathan P Ward, Nicolas Prieto-Farigua, …, Anish Thalakola, Mingxiang Teng, Gina M DeNicola
  • Redox Biol, 10.1016/j.redox.2022.102358
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Metabolism in tumor-associated macrophages

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Mitochondrial Calcium Uniporter Drives Metastasis and Confers a Targetable Cystine Dependency in Pancreatic Cancer

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Genetic tools for the stable overexpression of circular RNAs

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Connecting copper and cancer: from transition metal signalling to metalloplasia

  • Eva J Ge, Ashley I Bush, Angela Casini, …, Peng Yuan, Donita C Brady, Christopher J Chang
  • Nat Rev Cancer, 10.1038/s41568-021-00417-2
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Targeting NRF2 and Its Downstream Processes: Opportunities and Challenges

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