Academic lineage
- Bernhard Ø Palsson - Postdoctoral Associate
A generic avian physiologically-based kinetic (PBK) model and its application in three bird species
- Vanessa Baier, Alicia Paini, Stephan Schaller, …, Thomas G Preuss, Johannes Witt, David Heckmann
- Environ Int, 10.1016/j.envint.2022.107547
Energetic basis for bird ontogeny and egg-laying applied to the bobwhite quail
- Nina Marn, Konstadia Lika, Starrlight Augustine, …, Markus Ebeling, David Heckmann, Andre Gergs
- None, 10.1093/conphys/coac063
Quantitative Morphometric, Physiological, and Metabolic Characteristics of Chickens and Mallards for Physiologically Based Kinetic Model Development
- Colin G Scanes, Johannes Witt, Markus Ebeling, …, Audrey J Bone, Thomas G Preuss, David Heckmann
- None, 10.3389/fphys.2022.858283
Quantitative Comparison of Avian and Mammalian Physiologies for Parameterization of Physiologically Based Kinetic Models
- Colin G Scanes, Johannes Witt, Markus Ebeling, …, Audrey J Bone, Thomas G Preuss, David Heckmann
- None, 10.3389/fphys.2022.858386
Modeling photosynthetic resource allocation connects physiology with evolutionary environments
- Esther M Sundermann, Martin J Lercher, David Heckmann
- Sci Rep, 10.1038/s41598-021-94903-0
Independent component analysis recovers consistent regulatory signals from disparate datasets
- Anand V Sastry, Alyssa Hu, David Heckmann, Saugat Poudel, Erol Kavvas, Bernhard O Palsson
- PLoS Comput Biol, 10.1371/journal.pcbi.1008647
Kinetic profiling of metabolic specialists demonstrates stability and consistency of in vivo enzyme turnover numbers
- David Heckmann, Anaamika Campeau, Colton J Lloyd, …, Adam M Feist, David J Gonzalez, Bernhard O Palsson
- Proc Natl Acad Sci U S A, 10.1073/pnas.2001562117
A biochemically-interpretable machine learning classifier for microbial GWAS
- Erol S Kavvas, Laurence Yang, Jonathan M Monk, David Heckmann, Bernhard O Palsson
- Nat Commun, 10.1038/s41467-020-16310-9
Adaptations of Escherichia coli strains to oxidative stress are reflected in properties of their structural proteomes
- Nathan Mih, Jonathan M Monk, Xin Fang, …, David Heckmann, Laurence Yang, Bernhard O Palsson
- BMC Bioinformatics, 10.1186/s12859-020-3505-y
Cellular responses to reactive oxygen species are predicted from molecular mechanisms
- Laurence Yang, Nathan Mih, Amitesh Anand, …, Ying Hefner, Adam M Feist, Bernhard O Palsson
- Proc Natl Acad Sci U S A, 10.1073/pnas.1905039116
Modeling genome-wide enzyme evolution predicts strong epistasis underlying catalytic turnover rates
- David Heckmann, Daniel C Zielinski, Bernhard O Palsson
- Nat Commun, 10.1038/s41467-018-07649-1
Machine learning applied to enzyme turnover numbers reveals protein structural correlates and improves metabolic models
- David Heckmann, Colton J Lloyd, Nathan Mih, …, Abdelmoneim Amer Desouki, Martin J Lercher, Bernhard O Palsson
- Nat Commun, 10.1038/s41467-018-07652-6
Machine learning and structural analysis of Mycobacterium tuberculosis pan-genome identifies genetic signatures of antibiotic resistance
- Erol S Kavvas, Edward Catoiu, Nathan Mih, …, Victor Nizet, Jonathan M Monk, Bernhard O Palsson
- Nat Commun, 10.1038/s41467-018-06634-y