Scholar: Dana Branzei

Dana Branzei

Rad51-mediated replication of damaged templates relies on monoSUMOylated DDK kinase

  • Chinnu Rose Joseph, Sabrina Dusi, Michele Giannattasio, …, Sabrina Dusi, Michele Giannattasio, Dana Branzei
  • Nat Commun, 10.1038/s41467-022-30215-9
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Parental histone deposition on the replicated strands promotes error-free DNA damage tolerance and regulates drug resistance

  • Valeria Dolce, Sabrina Dusi, Michele Giannattasio, Chinnu Rose Joseph, Marco Fumasoni, Dana Branzei
  • Genes Dev, 10.1101/gad.349207.121
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Mutation in senataxin alters the mechanism of R-loop resolution in amyotrophic lateral sclerosis 4

  • Annapoorna Kannan, Juliana Cuartas, Pratik Gangwani, Dana Branzei, Laxman Gangwani
  • Brain, 10.1093/brain/awab464
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Computed structures of core eukaryotic protein complexes

  • Ian R Humphreys, Jimin Pei, Minkyung Baek, …, Tamara L Hendrickson, Qian Cong, David Baker
  • Science, 10.1126/science.abm4805
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Vertebrate CTF18 and DDX11 essential function in cohesion is bypassed by preventing WAPL-mediated cohesin release

  • Ryotaro Kawasumi, Takuya Abe, Ivan Psakhye, Keiji Miyata, Kouji Hirota, Dana Branzei
  • Genes Dev, 10.1101/gad.348581.121
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DNA helicases in homologous recombination repair

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DDX11 loss causes replication stress and pharmacologically exploitable DNA repair defects

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Smc5/6 functions with Sgs1-Top3-Rmi1 to complete chromosome replication at natural pause sites

  • Sumedha Agashe, Chinnu Rose Joseph, Teresa Anne Clarisse Reyes, …, Anja Waizenegger, Barnabas Szakal, Dana Branzei
  • Nat Commun, 10.1038/s41467-021-22217-w
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Mus81-Mms4 endonuclease is an Esc2-STUbL-Cullin8 mitotic substrate impacting on genome integrity

  • Anja Waizenegger, Madhusoodanan Urulangodi, Carl P Lehmann, …, José Antonio Tercero, Barnabas Szakal, Dana Branzei
  • Nat Commun, 10.1038/s41467-020-19503-4
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Prevention of unwanted recombination at damaged replication forks

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The Mgs1/WRNIP1 ATPase is required to prevent a recombination salvage pathway at damaged replication forks

  • Alberto Jiménez-Martín, Irene Saugar, Chinnu Rose Joseph, …, Barnabas Szakal, Dana Branzei, José Antonio Tercero
  • Sci Adv, 10.1126/sciadv.aaz3327
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SUMO-Chain-Regulated Proteasomal Degradation Timing Exemplified in DNA Replication Initiation

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Rad5 Recruits Error-Prone DNA Polymerases for Mutagenic Repair of ssDNA Gaps on Undamaged Templates

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