Academic lineage
- Jens Nielsen - PhD student
Controlling gene expression with deep generative design of regulatory DNA
- Jan Zrimec, Xiaozhi Fu, Azam Sheikh Muhammad, …, Florian David, Jens Nielsen, Aleksej Zelezniak
- Nat Commun, 10.1038/s41467-022-32818-8
Deep learning suggests that gene expression is encoded in all parts of a co-evolving interacting gene regulatory structure
- Jan Zrimec, Christoph S Börlin, Filip Buric, …, Jens Nielsen, Mats Töpel, Aleksej Zelezniak
- Nat Commun, 10.1038/s41467-020-19921-4
The transcription factor Leu3 shows differential binding behavior in response to changing leucine availability
- Christoph S Börlin, Jens Nielsen, Verena Siewers
- FEMS Microbiol Lett, 10.1093/femsle/fnaa107
A bioinformatic pipeline to analyze ChIP-exo datasets
- Christoph S Börlin, David Bergenholm, Petter Holland, Jens Nielsen
- None, 10.1093/biomethods/bpz011
Pharmacological polyamine catabolism upregulation with methionine salvage pathway inhibition as an effective prostate cancer therapy
- Hayley C Affronti, Aryn M Rowsam, Anthony J Pellerite, …, James G Phillips, Robert A Casero, Dominic J Smiraglia
- Nat Commun, 10.1038/s41467-019-13950-4
Predictive models of eukaryotic transcriptional regulation reveals changes in transcription factor roles and promoter usage between metabolic conditions
- Petter Holland, David Bergenholm, Christoph S Börlin, Guodong Liu, Jens Nielsen
- Nucleic Acids Res, 10.1093/nar/gkz253
Dietary folate levels alter the kinetics and molecular mechanism of prostate cancer recurrence in the CWR22 model
- Hayley C Affronti, Mark D Long, Spencer R Rosario, …, John H Wilton, Moray J Campbell, Dominic J Smiraglia
- Oncotarget, 10.18632/oncotarget.21911
Agent-based modeling of autophagy reveals emergent regulatory behavior of spatio-temporal autophagy dynamics
- Christoph S Börlin, Verena Lang, Anne Hamacher-Brady, Nathan R Brady
- Cell Commun Signal, 10.1186/s12964-014-0056-8