Machine Learning Identifies Chemical Characteristics That Promote Enzyme Catalysis
- Brian M Bonk, James W Weis, Bruce Tidor
- J Am Chem Soc, 10.1021/jacs.8b13879
Rational design of thiolase substrate specificity for metabolic engineering applications
- Brian M Bonk, Yekaterina Tarasova, Michael A Hicks, Bruce Tidor, Kristala L J Prather
- Biotechnol Bioeng, 10.1002/bit.26737
Strong Enrichment of Aromatic Residues in Binding Sites from a Charge-neutralized Hyperthermostable Sso7d Scaffold Library
- Michael W Traxlmayr, Jonathan D Kiefer, Raja R Srinivas, …, Nicole J Yang, Bruce Tidor, K Dane Wittrup
- J Biol Chem, 10.1074/jbc.m116.741314
A Fungal-Selective Cytochrome bc 1 Inhibitor Impairs Virulence and Prevents the Evolution of Drug Resistance
- Benjamin M Vincent, Jean-Baptiste Langlois, Raja Srinivas, …, Bruce Tidor, Stephen L Buchwald, Susan Lindquist
- Cell Chem Biol, 10.1016/j.chembiol.2016.06.016
Exploiting Temporal Collateral Sensitivity in Tumor Clonal Evolution
- Boyang Zhao, Joseph C Sedlak, Raja Srinivas, …, Bruce Tidor, Douglas A Lauffenburger, Michael T Hemann
- Cell, 10.1016/j.cell.2016.01.045