The small protein MntS evolved from a signal peptide and acquired a novel function regulating manganese homeostasis in Escherichia coli
- Zachary Wright, Mackenzie Seymour, Kalista Paszczak, …, Vivek Anantharaman, L Aravind, Lauren S Waters
- None, 10.1101/2023.06.02.543501
VirB, a key transcriptional regulator of Shigella virulence, requires a CTP ligand for its regulatory activities
- Taylor M Gerson, Audrey M Ott, Monika Ma Karney, …, L Aravind, Ronald K Gary, Helen J Wing
- None, 10.1101/2023.05.16.541010
Mechanism and evolutionary origins of Alanine-tail C-degron recognition by E3 ligases Pirh2 and CRL2-KLHDC10
- Pratik Rajendra Patil, A Maxwell Burroughs, Mohit Misra, …, Ivan Dikic, L Aravind, Claudio A P Joazeiro
- None, 10.1101/2023.05.03.539038
B. subtilis MutS2 splits stalled ribosomes into subunits without mRNA cleavage
- Esther Park, Timur Mackens-Kiani, Rebekah Berhane, …, Roland Beckmann, Rachel Green, Allen R Buskirk
- None, 10.1101/2023.05.05.539626
Bacterial NLR-related proteins protect against phage
- Emily M Kibby, Amy N Conte, A Maxwell Burroughs, …, Lindsay A Whalen, L Aravind, Aaron T Whiteley
- Cell, 10.1016/j.cell.2023.04.015
New biochemistry in the Rhodanese-phosphatase superfamily: emerging roles in diverse metabolic processes, nucleic acid modifications, and biological conflicts
- A Maxwell Burroughs, L Aravind, A Maxwell Burroughs, L Aravind
- None, 10.1093/nargab/lqad029
Discovering Biological Conflict Systems Through Genome Analysis: Evolutionary Principles and Biochemical Novelty
- L Aravind, Lakshminarayan M Iyer, A Maxwell Burroughs
- Annu Rev Biomed Data Sci, 10.1146/annurev-biodatasci-122220-101119
GATD3A, a mitochondrial deglycase with evolutionary origins from gammaproteobacteria, restricts the formation of advanced glycation end products
- Andrew J Smith, Jayshree Advani, Daniel C Brock, …, L Aravind, Breandán Kennedy, Anand Swaroop
- BMC Biol, 10.1186/s12915-022-01267-6
Ribosome collisions induce mRNA cleavage and ribosome rescue in bacteria
- Kazuki Saito, Hanna Kratzat, Annabelle Campbell, …, Rachel Green, Roland Beckmann, Allen R Buskirk
- Nature, 10.1038/s41586-022-04416-7
Bacterial developmental checkpoint that directly monitors cell surface morphogenesis
- Thomas Delerue, Vivek Anantharaman, Michael C Gilmore, …, Felipe Cava, L Aravind, Kumaran S Ramamurthi
- Dev Cell, 10.1016/j.devcel.2021.12.021
Babesia microti : Pathogen Genomics, Genetic Variability, Immunodominant Antigens, and Pathogenesis
- Ankit Puri, Surabhi Bajpai, Scott Meredith, L Aravind, Peter J Krause, Sanjai Kumar
- None, 10.3389/fmicb.2021.697669
Gene-teratogen interactions influence the penetrance of birth defects by altering Hedgehog signaling strength
- Jennifer H Kong, Cullen B Young, Ganesh V Pusapati, …, Teresa M Gunn, Cecilia W Lo, Rajat Rohatgi
- Development, 10.1242/dev.199867
Bacterial death and TRADD-N domains help define novel apoptosis and immunity mechanisms shared by prokaryotes and metazoans
- Gurmeet Kaur, Lakshminarayan M Iyer, A Maxwell Burroughs, L Aravind
- Elife, 10.7554/elife.70394
Reformulation of an extant ATPase active site to mimic ancestral GTPase activity reveals a nucleotide base requirement for function
- Taylor B Updegrove, Jailynn Harke, Vivek Anantharaman, …, Jue D Wang, L Aravind, Kumaran S Ramamurthi
- Elife, 10.7554/elife.65845
Unification and extensive diversification of M/Orf3-related ion channel proteins in coronaviruses and other nidoviruses
- Yongjun Tan, Theresa Schneider, Prakash K Shukla, Mahesh B Chandrasekharan, L Aravind, Dapeng Zhang
- None, 10.1093/ve/veab014
Jumbo Phages: A Comparative Genomic Overview of Core Functions and Adaptions for Biological Conflicts
- Lakshminarayan M Iyer, Vivek Anantharaman, Arunkumar Krishnan, A Maxwell Burroughs, L Aravind
- Viruses, 10.3390/v13010063