VirB, a key transcriptional regulator of Shigella virulence, requires a CTP ligand for its regulatory activities
- Taylor M Gerson, Audrey M Ott, Monika Ma Karney, …, L Aravind, Ronald K Gary, Helen J Wing
- None, 10.1101/2023.05.16.541010
Discovering Biological Conflict Systems Through Genome Analysis: Evolutionary Principles and Biochemical Novelty
- L Aravind, Lakshminarayan M Iyer, A Maxwell Burroughs
- Annu Rev Biomed Data Sci, 10.1146/annurev-biodatasci-122220-101119
Bacterial death and TRADD-N domains help define novel apoptosis and immunity mechanisms shared by prokaryotes and metazoans
- Gurmeet Kaur, Lakshminarayan M Iyer, A Maxwell Burroughs, L Aravind
- Elife, 10.7554/elife.70394
Jumbo Phages: A Comparative Genomic Overview of Core Functions and Adaptions for Biological Conflicts
- Lakshminarayan M Iyer, Vivek Anantharaman, Arunkumar Krishnan, A Maxwell Burroughs, L Aravind
- Viruses, 10.3390/v13010063
Comprehensive classification of ABC ATPases and their functional radiation in nucleoprotein dynamics and biological conflict systems
- Arunkumar Krishnan, A Maxwell Burroughs, Lakshminarayan M Iyer, L Aravind
- Nucleic Acids Res, 10.1093/nar/gkaa726
Mycobacterium tuberculosis Rv0991c Is a Redox-Regulated Molecular Chaperone
- Samuel H Becker, Kathrin Ulrich, Avantika Dhabaria, …, L Aravind, Ursula Jakob, K Heran Darwin
- mBio, 10.1128/mbio.01545-20
Corrigendum: The cyl Genes Reveal the Biosynthetic and Evolutionary Origins of the Group B Streptococcus Hemolytic Lipid, Granadaene
- Blair Armistead, Christopher Whidbey, Lakshminarayan M Iyer, …, Juan Manuel Cuerva, Heather B Jaspan, Lakshmi Rajagopal
- None, 10.3389/fmicb.2020.00325
Functional Innovation in the Evolution of the Calcium-Dependent System of the Eukaryotic Endoplasmic Reticulum
- Daniel E Schäffer, Lakshminarayan M Iyer, A Maxwell Burroughs, L Aravind
- None, 10.3389/fgene.2020.00034
Highly regulated, diversifying NTP-dependent biological conflict systems with implications for the emergence of multicellularity
- Gurmeet Kaur, A Maxwell Burroughs, Lakshminarayan M Iyer, L Aravind
- Elife, 10.7554/elife.52696
The catalytic core of DEMETER guides active DNA demethylation in Arabidopsis
- Changqing Zhang, Yu-Hung Hung, Hyun Jung Rim, …, Robert L Fischer, Jin Hoe Huh, Tzung-Fu Hsieh
- Proc Natl Acad Sci U S A, 10.1073/pnas.1907290116
Unexpected Evolution of Lesion-Recognition Modules in Eukaryotic NER and Kinetoplast DNA Dynamics Proteins from Bacterial Mobile Elements
- Arunkumar Krishnan, A Maxwell Burroughs, Lakshminarayan M Iyer, L Aravind
- None, 10.1016/j.isci.2018.10.017
Evolutionary convergence and divergence in archaeal chromosomal proteins and Chromo-like domains from bacteria and eukaryotes
- Gurmeet Kaur, Lakshminarayan M Iyer, Srikrishna Subramanian, L Aravind
- Sci Rep, 10.1038/s41598-018-24467-z
Diversification of AID/APOBEC-like deaminases in metazoa: multiplicity of clades and widespread roles in immunity
- Arunkumar Krishnan, Lakshminarayan M Iyer, Stephen J Holland, Thomas Boehm, L Aravind
- Proc Natl Acad Sci U S A, 10.1073/pnas.1720897115
Expansions, diversification, and interindividual copy number variations of AID/APOBEC family cytidine deaminase genes in lampreys
- Stephen J Holland, Lesley M Berghuis, Justin J King, …, Michael Schorpp, Mani Larijani, Thomas Boehm
- Proc Natl Acad Sci U S A, 10.1073/pnas.1720871115
A Nonhemolytic Group B Streptococcus Strain Exhibits Hypervirulence
- Claire Gendrin, Jay Vornhagen, Blair Armistead, …, Shannon D Manning, David M Aronoff, Lakshmi Rajagopal
- J Infect Dis, 10.1093/infdis/jix646
Polyvalent Proteins, a Pervasive Theme in the Intergenomic Biological Conflicts of Bacteriophages and Conjugative Elements
- Lakshminarayan M Iyer, A Maxwell Burroughs, Swadha Anand, Robson F de Souza, L Aravind
- J Bacteriol, 10.1128/jb.00245-17