Academic lineage
Independent rediploidization masks shared whole genome duplication in the sturgeon-paddlefish ancestor
- Anthony K Redmond, Dearbhaile Casey, Manu Kumar Gundappa, …, Manu Kumar Gundappa, Daniel J Macqueen, Aoife McLysaght
- Nat Commun, 10.1038/s41467-023-38714-z
De novo birth of functional microproteins in the human lineage
- Nikolaos Vakirlis, Zoe Vance, Kate M Duggan, …, Zoe Vance, Kate M Duggan, Aoife McLysaght
- Cell Rep, 10.1016/j.celrep.2022.111808
The deceptive simplicity of mendelian genetics
- Aoife McLysaght
- PLoS Biol, 10.1371/journal.pbio.3001691
Reconstruction of proto-vertebrate, proto-cyclostome and proto-gnathostome genomes provides new insights into early vertebrate evolution
- Yoichiro Nakatani, Prashant Shingate, Vydianathan Ravi, …, Aravind Prasad, Aoife McLysaght, Byrappa Venkatesh
- Nat Commun, 10.1038/s41467-021-24573-z
fagin: synteny-based phylostratigraphy and finer classification of young genes
- Zebulun Arendsee, Jing Li, Urminder Singh, Priyanka Bhandary, Arun Seetharam, Eve Syrkin Wurtele
- BMC Bioinformatics, 10.1186/s12859-019-3023-y
Macrosynteny analysis shows the absence of ancient whole-genome duplication in lepidopteran insects
- Yoichiro Nakatani, Aoife McLysaght
- Proc Natl Acad Sci U S A, 10.1073/pnas.1817937116
Computational Prediction of De Novo Emerged Protein-Coding Genes
- Nikolaos Vakirlis, Aoife McLysaght
- Methods Mol Biol, 10.1007/978-1-4939-8736-8_4
Pseudogenes Provide Evolutionary Evidence for the Competitive Endogenous RNA Hypothesis
- Cian Glenfield, Aoife McLysaght
- Mol Biol Evol, 10.1093/molbev/msy183
A Family of Vertebrate-Specific Polycombs Encoded by the LCOR/LCORL Genes Balance PRC2 Subtype Activities
- Eric Conway, Emilia Jerman, Evan Healy, …, Raphaël Margueron, Haruhiko Koseki, Adrian P Bracken
- Mol Cell, 10.1016/j.molcel.2018.03.005
Faster Evolving Primate Genes Are More Likely to Duplicate
- Áine N O’Toole, Laurence D Hurst, Aoife McLysaght
- Mol Biol Evol, 10.1093/molbev/msx270
Genomes as documents of evolutionary history: a probabilistic macrosynteny model for the reconstruction of ancestral genomes
- Yoichiro Nakatani, Aoife McLysaght
- Bioinformatics, 10.1093/bioinformatics/btx259
Dosage-sensitive genes in evolution and disease
- Alan M Rice, Aoife McLysaght
- BMC Biol, 10.1186/s12915-017-0418-y
Dosage sensitivity is a major determinant of human copy number variant pathogenicity
- Alan M Rice, Aoife McLysaght
- Nat Commun, 10.1038/ncomms14366
Spatial Colocalization of Human Ohnolog Pairs Acts to Maintain Dosage-Balance
- Ting Xie, Qing-Yong Yang, Xiao-Tao Wang, Aoife McLysaght, Hong-Yu Zhang
- Mol Biol Evol, 10.1093/molbev/msw108