Candida auris uses metabolic strategies to escape and kill macrophages while avoiding robust activation of the NLRP3 inflammasome response
- Harshini Weerasinghe, Claudia Simm, Tirta Mario Djajawi, …, Kate E Lawlor, Ronen Ben-Ami, Ana Traven
- Cell Rep, 10.1016/j.celrep.2023.112522
The proteasome regulator Rpn4 controls antifungal drug tolerance by coupling protein homeostasis with metabolic responses to drug stress
- Ka Pui Sharon Yau, Harshini Weerasinghe, Francios A B Olivier, …, Barbara Koch, Traude H Beilharz, Ana Traven
- PLoS Pathog, 10.1371/journal.ppat.1011338
The escape of Candida albicans from macrophages is enabled by the fungal toxin candidalysin and two host cell death pathways
- Françios A B Olivier, Volker Hilsenstein, Harshini Weerasinghe, …, James E Vince, Michael J Hickey, Ana Traven
- Cell Rep, 10.1016/j.celrep.2022.111374
Disruption of Iron Homeostasis and Mitochondrial Metabolism Are Promising Targets to Inhibit Candida auris
- Claudia Simm, Harshini Weerasinghe, David R Thomas, …, Hayley J Newton, Traude H Beilharz, Ana Traven
- Microbiol Spectr, 10.1128/spectrum.00100-22
The RSC (Remodels the Structure of Chromatin) complex of Candida albicans shows compositional divergence with distinct roles in regulating pathogenic traits
- Vinutha K Balachandra, Jiyoti Verma, Madhu Shankar, …, Ana Traven, Ralf B Schittenhelm, Santanu K Ghosh
- PLoS Genet, 10.1371/journal.pgen.1009071
Natural Variation in Clinical Isolates of Candida albicans Modulates Neutrophil Responses
- Madhu Shankar, Tricia L Lo, Ana Traven
- mSphere, 10.1128/msphere.00501-20
Immunometabolism in fungal infections: the need to eat to compete
- Harshini Weerasinghe, Ana Traven
- Curr Opin Microbiol, 10.1016/j.mib.2020.07.001
Metabolic competition between host and pathogen dictates inflammasome responses to fungal infection
- Timothy M Tucey, Jiyoti Verma, Françios A B Olivier, …, Avril A B Robertson, Thomas Naderer, Ana Traven
- PLoS Pathog, 10.1371/journal.ppat.1008695
Targeting NLRP3 and Staphylococcal pore-forming toxin receptors in human-induced pluripotent stem cell-derived macrophages
- Seong H Chow, Pankaj Deo, Amy T Y Yeung, …, Gordon Dougan, Anton Y Peleg, Thomas Naderer
- J Leukoc Biol, 10.1002/jlb.4ma0420-497r
The YEATS Domain Histone Crotonylation Readers Control Virulence-Related Biology of a Major Human Pathogen
- Qi Wang, Jiyoti Verma, Nikolina Vidan, …, Mary Sopta, Traude H Beilharz, Ana Traven
- Cell Rep, 10.1016/j.celrep.2020.107528
Mitochondrial Control of Fungal Cell Walls: Models and Relevance in Fungal Pathogens
- Barbara Koch, Ana Traven
- Curr Top Microbiol Immunol, 10.1007/82_2019_183
Central metabolic interactions of immune cells and microbes: prospects for defeating infections
- Ana Traven, Thomas Naderer
- EMBO Rep, 10.15252/embr.201947995
Mdivi-1 and mitochondrial fission: recent insights from fungal pathogens
- Barbara Koch, Ana Traven
- Curr Genet, 10.1007/s00294-019-00942-6
A Metabolic Checkpoint for the Yeast-to-Hyphae Developmental Switch Regulated by Endogenous Nitric Oxide Signaling
- Barbara Koch, Adele A Barugahare, Tricia L Lo, …, David R Powell, Traude H Beilharz, Ana Traven
- Cell Rep, 10.1016/j.celrep.2018.10.080
Glucose Homeostasis Is Important for Immune Cell Viability during Candida Challenge and Host Survival of Systemic Fungal Infection
- Timothy M Tucey, Jiyoti Verma, Paul F Harrison, …, Traude H Beilharz, Thomas Naderer, Ana Traven
- Cell Metab, 10.1016/j.cmet.2018.03.019
The Mitochondrial GTPase Gem1 Contributes to the Cell Wall Stress Response and Invasive Growth of Candida albicans
- Barbara Koch, Timothy M Tucey, Tricia L Lo, Stevan Novakovic, Peter Boag, Ana Traven
- None, 10.3389/fmicb.2017.02555