Systems biology elucidates the distinctive metabolic niche filled by the human gut microbe Eggerthella lenta
- Cecilia Noecker, Juan Sanchez, Jordan E Bisanz, …, Ines Thiele, Brian C DeFelice, Peter J Turnbaugh
- PLoS Biol, 10.1371/journal.pbio.3002125
Genome-scale metabolic reconstruction of 7,302 human microorganisms for personalized medicine
- Almut Heinken, Johannes Hertel, Geeta Acharya, …, Christopher S Henry, Ronan M T Fleming, Ines Thiele
- Nat Biotechnol, 10.1038/s41587-022-01628-0
The gut microbial metabolite formate exacerbates colorectal cancer progression
- Dominik Ternes, Mina Tsenkova, Vitaly Igorevich Pozdeev, …, Serge Haan, Paul Wilmes, Elisabeth Letellier
- Nat Metab, 10.1038/s42255-022-00558-0
Microbiome Modelling Toolbox 2.0: Efficient, tractable modelling of microbiome communities
- Almut Heinken, Ines Thiele, Almut Heinken, …, Ines Thiele, Almut Heinken, Ines Thiele
- Bioinformatics, 10.1093/bioinformatics/btac082
DEMETER: efficient simultaneous curation of genome-scale reconstructions guided by experimental data and refined gene annotations
- Almut Heinken, StefanÃa Magnúsdóttir, Ronan M T Fleming, …, StefanÃa Magnúsdóttir, Ronan M T Fleming, Ines Thiele
- Bioinformatics, 10.1093/bioinformatics/btab622
Genome-Scale Metabolic Modeling of the Human Microbiome in the Era of Personalized Medicine
- Almut Heinken, Arianna Basile, Johannes Hertel, Cyrille Thinnes, Ines Thiele
- Annu Rev Microbiol, 10.1146/annurev-micro-060221-012134
Integration of constraint-based modeling with fecal metabolomics reveals large deleterious effects of Fusobacterium spp. on community butyrate production
- Johannes Hertel, Almut Heinken, Filippo Martinelli, Ines Thiele
- Gut Microbes, 10.1080/19490976.2021.1915673
Metabolic modelling reveals broad changes in gut microbial metabolism in inflammatory bowel disease patients with dysbiosis
- Almut Heinken, Johannes Hertel, Ines Thiele
- NPJ Syst Biol Appl, 10.1038/s41540-021-00178-6
The contribution of gut bacterial metabolites in the human immune signaling pathway of non-communicable diseases
- F Hosseinkhani, A Heinken, I Thiele, P W Lindenburg, A C Harms, T Hankemeier
- Gut Microbes, 10.1080/19490976.2021.1882927
Brain-gut-microbiome interactions in obesity and food addiction
- Arpana Gupta, Vadim Osadchiy, Emeran A Mayer
- Nat Rev Gastroenterol Hepatol, 10.1038/s41575-020-0341-5