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2023 Articles
1 518 articles
Emerging diagnostics and therapeutics for Alzheimer disease
- Wade K Self, David M Holtzman
- Nat Med, 10.1038/s41591-023-02505-2
The complex genetic architecture of Alzheimer’s disease: novel insights and future directions
- Shea J Andrews, Alan E Renton, Brian Fulton-Howard, …, Anna Podlesny-Drabiniok, Edoardo Marcora, Alison M Goate
- EBioMedicine, 10.1016/j.ebiom.2023.104511
The effect of Abi3 locus deletion on the progression of Alzheimer’s disease-related pathologies
- Hande Karahan, Daniel C Smith, Byungwook Kim, …, Md Mamun Al-Amin, Luke C Dabin, Jungsu Kim
- Front Immunol, 10.3389/fimmu.2023.1102530
Humanized APOE genotypes influence lifespan independently of tau aggregation in the P301S mouse model of tauopathy
- Tristan Williams, Tim Bathe, Quan Vo, …, David R Borchelt, Stefan Prokop, Paramita Chakrabarty
- Acta Neuropathol Commun, 10.1186/s40478-023-01581-2
Impact of apolipoprotein E isoforms on sporadic Alzheimer’s disease: beyond the role of amyloid beta
- Madia Lozupone, Francesco Panza, Madia Lozupone, Francesco Panza, Madia Lozupone, Francesco Panza
- None, 10.4103/1673-5374.375316
Resilient brains run out of (c)GAS
- Andrea Francesca M Salvador, Andrea Francesca M Salvador, Andrea Francesca M Salvador, …, Jonathan Kipnis, Andrea Francesca M Salvador, Jonathan Kipnis
- Nat Immunol, 10.1038/s41590-023-01485-2
Expression of INPP5D Isoforms in Human Brain: Impact of Alzheimer’s Disease Neuropathology and Genetics
- Diana J Zajac, James Simpson, Eric Zhang, …, Eric Zhang, Ishita Parikh, Steven Estus
- Genes (Basel), 10.3390/genes14030763
INPP5D modulates TREM2 loss-of-function phenotypes in a β-amyloidosis mouse model
- Akihiro Iguchi, Sho Takatori, Shingo Kimura, …, Toshiyuki Takai, Takehiko Sasaki, Taisuke Tomita
- None, 10.1016/j.isci.2023.106375
Accumulation of m 6 A exhibits stronger correlation with MAPT than β-amyloid pathology in an APP NL-G-F /MAPT P301S mouse model of Alzheimer’s disease
- Lulu Jiang, Rebecca Roberts, Melissa Wong, …, Takashi Saito, Takaomi C Saido, Benjamin Wolozin
- bioRxiv : the preprint server for biology, 10.1101/2023.03.28.534515
Genetic architecture of plasma Alzheimer disease biomarkers
- Joseph Bradley, Priyanka Gorijala, Suzanne E Schindler, …, Beau Ances, Maria V Fernandez, Carlos Cruchaga
- Hum Mol Genet, 10.1093/hmg/ddad087
2022 Articles
137 articles
TREM2 dependent and independent functions of microglia in Alzheimer’s disease
- Jinchao Hou, Yun Chen, Gary Grajales-Reyes, …, Yun Chen, Gary Grajales-Reyes, Marco Colonna
- Mol Neurodegener, 10.1186/s13024-022-00588-y
Novel Genetic Variants in TP37, PIK3R1, CALM1, and PLCG2 of the Neurotrophin Signaling Pathway Are Associated with the Progression from Mild Cognitive Impairment to Alzheimer’s Disease
- Huiyue Li, Hongliang Liu, Michael W Lutz, …, Hongliang Liu, Michael W Lutz, Sheng Luo
- J Alzheimers Dis, 10.3233/jad-220680
A primary rodent triculture model to investigate the role of glia-neuron crosstalk in regulation of neuronal activity
- Leela Phadke, Dawn H W Lau, Nozie D Aghaizu, …, Lorenza Magno, Paul Whiting, Sarah Jolly
- None, 10.3389/fnagi.2022.1056067
Golgi apparatus, endoplasmic reticulum and mitochondrial function implicated in Alzheimer’s disease through polygenic risk and RNA sequencing
- Karen Crawford, Ganna Leonenko, Emily Baker, …, Michael C O’Donovan, Valentina Escott-Price, Dobril K Ivanov
- Mol Psychiatry, 10.1038/s41380-022-01926-8
PICALM and Alzheimer’s Disease: An Update and Perspectives
- Kunie Ando, Siranjeevi Nagaraj, Fahri Küçükali, …, Lidia Lopez Gutierrez, Jean-Pierre Brion, Karelle Leroy
- Cells, 10.3390/cells11243994
Polygenic Effect on Tau Pathology Progression in Alzheimer’s Disease
- Anna Rubinski, Simon Frerich, Rainer Malik, …, Alfredo Ramirez, Martin Dichgans, Michael Ewers
- Ann Neurol, 10.1002/ana.26588
Soluble TREM2 levels associate with conversion from mild cognitive impairment to Alzheimer’s disease
- Aonan Zhao, Yang Jiao, Guanyu Ye, …, Yuanyuan Li, Yulei Deng, Jun Liu
- J Clin Invest, 10.1172/jci158708
Amyloid-beta and tau pathologies act synergistically to induce novel disease stage-specific microglia subtypes
- Dong Won Kim, Kevin J Tu, Alice Wei, …, Seth Blackshaw, Ronald L Schnaar, Tong Li
- Mol Neurodegener, 10.1186/s13024-022-00589-x
INPP5D deficiency attenuates amyloid pathology in a mouse model of Alzheimer’s disease
- Peter Bor-Chian Lin, Andy Po-Yi Tsai, Disha Soni, …, Gary E Landreth, Bruce T Lamb, Adrian L Oblak
- Alzheimers Dement, 10.1002/alz.12849
Spatially resolved transcriptomics reveals genes associated with the vulnerability of middle temporal gyrus in Alzheimer’s disease
- Shuo Chen, Yuzhou Chang, Liangping Li, …, Karen E Duff, Qin Ma, Hongjun Fu
- Acta Neuropathol Commun, 10.1186/s40478-022-01494-6