Channel: Peroxisome redox homeostasis in yeasts

Inspired by: Yilan Liu, Anna Khusnutdinova

Peroxisomes are vital cellular organelles involved in numerous metabolic processes, including the breakdown of fatty acids through beta-oxidation. Given the nature of these metabolic reactions, peroxisomes inherently produce reactive oxygen species (ROS), such as hydrogen peroxide (Hâ‚‚Oâ‚‚). Therefore, maintaining redox homeostasis within these organelles is crucial to ensure cellular health and function. ChatGPT (CC BY 4.0)

2023 Articles

797 articles

Gaining access to acetyl-CoA by peroxisomal surface display

  • Thomas Perrot, Sébastien Besseau, Nicolas Papon, …, Sébastien Besseau, Nicolas Papon, Vincent Courdavault
  • None, 10.1016/j.synbio.2023.02.003
Comment Section

Characterization of Yeast Peroxisomes: Enrichment of Peroxisomal Fractions and Analysis of β-Oxidation Activity

  • Carlo van Roermund, Ewald Hettema, Carlo van Roermund, …, Ewald Hettema, Carlo van Roermund, Ewald Hettema
  • Methods Mol Biol, 10.1007/978-1-0716-3048-8_22
Comment Section

Novel targeting assay uncovers targeting information within peroxisomal ABC transporter Pxa1

  • Renate L M Jansen, Marco van den Noort, Arjen M Krikken, …, Maya Schuldiner, Einat Zalckvar, Ida J van der Klei
  • Biochim Biophys Acta Mol Cell Res, 10.1016/j.bbamcr.2023.119471
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The dynamin-related protein Vps1 and the peroxisomal membrane protein Pex27 function together during peroxisome fission

  • Lakhan Ekal, Abdulaziz Ms Alqahtani, Ewald H Hettema, …, Lakhan Ekal, Abdulaziz M S Alqahtani, Ewald H Hettema
  • J Cell Sci, 10.1242/jcs.246348
Comment Section

Spindle Position Checkpoint Kinase Kin4 Regulates Organelle Transport in Saccharomyces cerevisiae

  • Lakhan Ekal, Abdulaziz M S Alqahtani, Maya Schuldiner, …, Einat Zalckvar, Ewald H Hettema, Kathryn R Ayscough
  • Biomolecules, 10.3390/biom13071098
Comment Section

Gluing yeast peroxisomes – composition and function of membrane contact sites

  • Fei Wu, Rinse de Boer, Ida J van der Klei, …, Fei Wu, Rinse de Boer, Ida J van der Klei
  • J Cell Sci, 10.1242/jcs.259440
Comment Section

The yeast transcription factor Stb5 acts as a negative regulator of autophagy by modulating cellular metabolism

  • Elizabeth Delorme-Axford, Xin Wen, Daniel J Klionsky, …, Elizabeth Delorme-Axford, Xin Wen, Daniel J Klionsky
  • Autophagy, 10.1080/15548627.2023.2228533
Comment Section

Import and quality control of peroxisomal proteins

  • Markus Rudowitz, Ralf Erdmann, Markus Rudowitz, Ralf Erdmann
  • J Cell Sci, 10.1242/jcs.260999
Comment Section

Acyl CoA oxidase: from its expression, structure, folding, and import to its role in human health and disease

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Molecular basis of the glycosomal targeting of PEX11 and its mislocalization to mitochondrion in trypanosomes

  • Chethan K Krishna, Nadine Schmidt, Bettina G Tippler, …, Konstanze F Winklhofer, Ralf Erdmann, Vishal C Kalel
  • None, 10.3389/fcell.2023.1213761
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2022 Articles

76 articles

PEX13 prevents pexophagy by regulating ubiquitinated PEX5 and peroxisomal ROS

Comment Section

Protein import into peroxisomes occurs through a nuclear pore-like phase

  • Yuan Gao, Michael L Skowyra, Peiqiang Feng, …, Michael L Skowyra, Peiqiang Feng, Tom A Rapoport
  • Science, 10.1126/science.adf3971
Comment Section

Spatial-temporal regulation of fatty alcohol biosynthesis in yeast

Comment Section

Ubiquitin-Conjugating Enzymes Ubc1 and Ubc4 Mediate the Turnover of Hap4, a Master Regulator of Mitochondrial Biogenesis in Saccharomyces cerevisiae

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Genetic defects in peroxisome morphogenesis (Pex11β, dynamin-like protein 1, and nucleoside diphosphate kinase 3) affect docosahexaenoic acid-phospholipid metabolism

  • Yuichi Abe, Ronald J A Wanders, Hans R Waterham, …, Tzipora C Falik-Zaccai, Naotada Ishihara, Yukio Fujiki
  • J Inherit Metab Dis, 10.1002/jimd.12582
Comment Section

Boosting lignan-precursor synthesis in yeast cell factories through co-factor supply optimization

  • Jennifer Perrin, Sébastien Besseau, Nicolas Papon, …, Sébastien Besseau, Nicolas Papon, Vincent Courdavault
  • None, 10.3389/fbioe.2022.1079801
Comment Section

Multi-omics network model reveals key genes associated with p-coumaric acid stress response in an industrial yeast strain

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Engineering Pheromone-Mediated Quorum Sensing with Enhanced Response Output Increases Fucosyllactose Production in Saccharomyces cerevisiae

  • Mingyuan Xu, Mengtong Sun, Xiangfeng Meng, …, Weixin Zhang, Yu Shen, Weifeng Liu
  • ACS Synth Biol, 10.1021/acssynbio.2c00507
Comment Section

Zcf24, a zinc-finger transcription factor, is required for lactate catabolism and inhibits commensalism in Candida albicans

  • Qiangqiang Sun, Bin Dong, Dandan Yang, …, Lianjuan Yang, Yang Lu, Chang Su
  • Mol Microbiol, 10.1111/mmi.15015
Comment Section

Comparison of human PEX knockout cell lines suggests a dual role of PEX1 in peroxisome biogenesis

  • Julia Ott, Jessica Sehr, Nadine Schmidt, …, Nadine Schmidt, Wolfgang Schliebs, Ralf Erdmann
  • Biol Chem, 10.1515/hsz-2022-0223
Comment Section