Metallothionein (MT) is a family of cysteine-rich, low molecular weight (MW ranging from 500 to 14000 Da) proteins. They are localized to the membrane of the Golgi apparatus. MTs have the capacity to bind both physiological (such as zinc, copper, selenium) and xenobiotic (such as cadmium, mercury, silver, arsenic, lead) heavy metals through the thiol group of its cysteine residues, which represent nearly 30% of its constituent amino acid residues. Wikipedia (CC BY-SA 3.0)
2023 Articles
910 articles
Zinc binding of a Cys2His2-type zinc finger protein is enhanced by the interaction with DNA
- Bálint Hajdu, Éva Hunyadi-Gulyás, Kohsuke Kato, …, Atsushi Kawaguchi, Kyosuke Nagata, Béla Gyurcsik
- J Biol Inorg Chem, 10.1007/s00775-023-01988-1
The past, present, and future of artificial zinc finger proteins: design strategies and chemical and biological applications
- Miki Imanishi, Mami Hamori, Yuka Kawahara-Nakagawa, …, Kanae Kishi, Nobuhito Shibata, Yukio Sugiura
- J Biol Inorg Chem, 10.1007/s00775-023-01991-6
Rational engineering of an elevator-type metal transporter ZIP8 reveals a conditional selectivity filter critically involved in determining substrate specificity
- Yuhan Jiang, Zhen Li, Dexin Sui, …, Hideki Takahashi, Kenneth Merz, Jian Hu
- Commun Biol, 10.1038/s42003-023-05146-w
OaAEP1 Ligase-Assisted Chemoenzymatic Synthesis of Full Cysteine-Rich Metal-Binding Cyanobacterial Metallothionein SmtA
- Anastasiia Antonenko, Avinash Kumar Singh, Karolina Mosna, …, Avinash Kumar Singh, Karolina Mosna, Artur Krężel
- Bioconjug Chem, 10.1021/acs.bioconjchem.3c00037
Engineered nickel bioaccumulation in Escherichia coli by NikABCDE transporter and metallothionein overexpression
- Patrick Diep, Heping Leo Shen, Julian A Wiesner, …, Vladimiros Papangelakis, Alexander F Yakunin, Radhakrishnan Mahadevan
- None, 10.1002/elsc.202200133
Copper-inducible expression system for metabolic engineering of Escherichia coli
- Lingrui Liu, Lu Zhang, Junyi Wang, …, Junyi Wang, Mingfeng Cao, Jifeng Yuan
- J Appl Microbiol, 10.1093/jambio/lxad109
Biochemical and molecular characterization of a novel porphobilinogen synthase from Corynebacterium glutamicum
- Di Zhu, Caiyun Wu, Chenxin Niu, …, Hong Li, Fanglan Ge, Wei Li
- World J Microbiol Biotechnol, 10.1007/s11274-023-03615-2
Moving metals: How microbes deliver metal cofactors to metalloproteins
- Dillon E Kunkle, Eric P Skaar, Dillon E Kunkle, …, Eric P Skaar, Dillon E Kunkle, Eric P Skaar
- Mol Microbiol, 10.1111/mmi.15117
Quantifying metal-binding specificity of CcNikZ-II from Clostridium carboxidivorans in the presence of competing metal ions
- Patrick Diep, Brayden Kell, Alexander Yakunin, …, Alexander Yakunin, Andreas Hilfinger, Radhakrishnan Mahadevan
- Anal Biochem, 10.1016/j.ab.2023.115182
Chimeric MerR-Family Regulators and Logic Elements for the Design of Metal Sensitive Genetic Circuits in Bacillus subtilis
- Jasdeep S Ghataora, Susanne Gebhard, Bianca J Reeksting, …, Jasdeep S Ghataora, Susanne Gebhard, Bianca J Reeksting
- ACS Synth Biol, 10.1021/acssynbio.2c00545
2022 Articles
93 articles
Principles to recover copper-conducting CTR proteins for the purpose of structural and functional studies
- Niloofar Nayeri, Ping Li, Kamil Górecki, …, Kamil Górecki, Karin Lindkvist-Petersson, Pontus Gourdon
- Protein Expr Purif, 10.1016/j.pep.2022.106213
Microbial remediation mechanisms and applications for lead-contaminated environments
- Bing Shan, Ruixia Hao, Junman Zhang, …, Jiani Li, Yubo Ye, Anhuai Lu
- World J Microbiol Biotechnol, 10.1007/s11274-022-03484-1
A novel copper-sensing two-component system for inducing Dsb gene expression in bacteria
- Liang Yu, Qiao Cao, Weizhong Chen, …, Min Wu, Taeok Bae, Lefu Lan
- Sci Bull (Beijing), 10.1016/j.scib.2021.03.003
Zur and zinc increase expression of E. coli ribosomal protein L31 through RNA-mediated repression of the repressor L31p
- Rebecca A Rasmussen, Suning Wang, Jeannie M Camarillo, …, Young Ah Goo, Julius B Lucks, Thomas V O’Halloran
- Nucleic Acids Res, 10.1093/nar/gkac1086
Relaxation-based NMR assignment: Spotlights on ligand binding sites in human CISD3
- Deborah Grifagni, José M Silva, Francesca Cantini, …, Francesca Cantini, Mario Piccioli, Lucia Banci
- J Inorg Biochem, 10.1016/j.jinorgbio.2022.112089
Maturation strategy influences expression levels and cofactor occupancy in Fe-S proteins
- Melissa Jansing, Steffen Mielenbrink, Hannah Rosenbach, …, Hannah Rosenbach, Sabine Metzger, Ingrid Span
- J Biol Inorg Chem, 10.1007/s00775-022-01972-1
Systematic engineering of Saccharomyces cerevisiae for efficient synthesis of hemoglobins and myoglobins
- Jike Xue, Jingwen Zhou, Jianghua Li, …, Jian Chen, Miao Wang, Xinrui Zhao
- Bioresour Technol, 10.1016/j.biortech.2022.128556
The Periodic Table’s Impact on Bioinorganic Chemistry and Biology’s Selective Use of Metal Ions
- Ambika Bhagi-Damodaran, Yi Lu, Ambika Bhagi-Damodaran, …, Yi Lu, Ambika Bhagi-Damodaran, Yi Lu
- None, 10.1007/430_2019_45
Microbial (E)-4-hydroxy-3-methylbut-2-enyl pyrophosphate reductase (IspH) and its biotechnological potential: A mini review
- Shiyong Huang, Yanfen Xue, Yanhe Ma, …, Yanfen Xue, Yanhe Ma, Cheng Zhou
- None, 10.3389/fbioe.2022.1057938
Physio-Biochemical and Transcriptomic Features of Arbuscular Mycorrhizal Fungi Relieving Cadmium Stress in Wheat
- Hua Li, Hongxia Wang, Jianan Zhao, …, Huixin Teng, Zuli Yuan, Zhiliang Yuan
- None, 10.3390/antiox11122390