Hepatocyte SREBP signaling mediates clock communication within the liver
- Dongyin Guan, Hosung Bae, Dishu Zhou, …, Bishuang Cai, Cholsoon Jang, Mitchell A Lazar
- J Clin Invest, 10.1172/jci163018
RIP140 deficiency enhances cardiac fuel metabolism and protects mice from heart failure
- Tsunehisa Yamamoto, Santosh K Maurya, Elizabeth Pruzinsky, …, Mitchell A Lazar, E Douglas Lewandowski, Daniel P Kelly
- J Clin Invest, 10.1172/jci162309
Hepatocytes demarcated by EphB2 contribute to the progression of nonalcoholic steatohepatitis
- Yang Xiao, Kirill Batmanov, Wenxiang Hu, …, Yifan Liu, David A Hill, Mitchell A Lazar
- Sci Transl Med, 10.1126/scitranslmed.adc9653
Circadian REV-ERBs repress E4bp4 to activate NAMPT-dependent NAD + biosynthesis and sustain cardiac function
- Pieterjan Dierickx, Kun Zhu, Bryce J Carpenter, …, Joseph A Baur, Martin E Young, Mitchell A Lazar
- None, 10.1038/s44161-021-00001-9
Individual-specific functional epigenomics reveals genetic determinants of adverse metabolic effects of glucocorticoids
- Wenxiang Hu, Chunjie Jiang, Mindy Kim, …, Ching-Hon Pui, Mary V Relling, Mitchell A Lazar
- Cell Metab, 10.1016/j.cmet.2021.06.004
Nuclear receptors and transcriptional regulation in non-alcoholic fatty liver disease
- Yang Xiao, Mindy Kim, Mitchell A Lazar
- Mol Metab, 10.1016/j.molmet.2020.101119
The hepatocyte clock and feeding control chronophysiology of multiple liver cell types
- Dongyin Guan, Ying Xiong, Trang Minh Trinh, …, Cholsoon Jang, Joshua D Rabinowitz, Mitchell A Lazar
- Science, 10.1126/science.aba8984
Dysregulated lncRNA-miRNA-mRNA Network Reveals Patient Survival-Associated Modules and RNA Binding Proteins in Invasive Breast Carcinoma
- Yu Dong, Yang Xiao, Qihui Shi, Chunjie Jiang
- None, 10.3389/fgene.2019.01284
Hippo pathway deletion in adult resting cardiac fibroblasts initiates a cell state transition with spontaneous and self-sustaining fibrosis
- Yang Xiao, Matthew C Hill, Lele Li, …, Thomas J Martin, Jun Wang, James F Martin
- Genes Dev, 10.1101/gad.329763.119
Tet inactivation disrupts YY1 binding and long-range chromatin interactions during embryonic heart development
- Shaohai Fang, Jia Li, Yang Xiao, …, Deqiang Sun, James F Martin, Yun Huang
- Nat Commun, 10.1038/s41467-019-12325-z
Hippo Signaling Plays an Essential Role in Cell State Transitions during Cardiac Fibroblast Development
- Yang Xiao, Matthew C Hill, Min Zhang, …, Alexander R Moise, Joshua D Wythe, James F Martin
- Dev Cell, 10.1016/j.devcel.2018.03.019
Hippo/Yap Signaling in Cardiac Development and Regeneration
- Yang Xiao, John Leach, Jun Wang, James F Martin
- None, 10.1007/s11936-016-0461-y
Yap and Taz play a crucial role in neural crest-derived craniofacial development
- Jun Wang, Yang Xiao, Chih-Wei Hsu, …, Mary E Dickinson, Joshua D Wythe, James F Martin
- Development, 10.1242/dev.126920
Actin cytoskeletal remodeling with protrusion formation is essential for heart regeneration in Hippo-deficient mice
- Yuka Morikawa, Min Zhang, Todd Heallen, …, Wei Li, James T Willerson, James F Martin
- Sci Signal, 10.1126/scisignal.2005781