Hepatocyte SREBP signaling mediates clock communication within the liver
- Dongyin Guan, Hosung Bae, Dishu Zhou, …, Bishuang Cai, Cholsoon Jang, Mitchell A Lazar
- J Clin Invest, 10.1172/jci163018
Editorial: Novel insights into the pathophysiology of diabetes-related complications: Implications for improved therapeutic strategies
- Jian Ma, Chunjie Jiang, Xuebin Fu, …, Jun Chen, Wenxiang Hu, Lin Yuan
- Front Endocrinol (Lausanne), 10.3389/fendo.2023.1157807
Hepatocytes demarcated by EphB2 contribute to the progression of nonalcoholic steatohepatitis
- Yang Xiao, Kirill Batmanov, Wenxiang Hu, …, Yifan Liu, David A Hill, Mitchell A Lazar
- Sci Transl Med, 10.1126/scitranslmed.adc9653
Modelling metabolic diseases and drug response using stem cells and organoids
- Wenxiang Hu, Mitchell A Lazar
- Nat Rev Endocrinol, 10.1038/s41574-022-00733-z
Individual-specific functional epigenomics reveals genetic determinants of adverse metabolic effects of glucocorticoids
- Wenxiang Hu, Chunjie Jiang, Mindy Kim, …, Ching-Hon Pui, Mary V Relling, Mitchell A Lazar
- Cell Metab, 10.1016/j.cmet.2021.06.004
The hepatocyte clock and feeding control chronophysiology of multiple liver cell types
- Dongyin Guan, Ying Xiong, Trang Minh Trinh, …, Cholsoon Jang, Joshua D Rabinowitz, Mitchell A Lazar
- Science, 10.1126/science.aba8984
Patient Adipose Stem Cell-Derived Adipocytes Reveal Genetic Variation that Predicts Antidiabetic Drug Response
- Wenxiang Hu, Chunjie Jiang, Dongyin Guan, …, Weiping Jia, Raymond E Soccio, Mitchell A Lazar
- Cell Stem Cell, 10.1016/j.stem.2018.11.018
Diet-Induced Circadian Enhancer Remodeling Synchronizes Opposing Hepatic Lipid Metabolic Processes
- Dongyin Guan, Ying Xiong, Patricia C Borck, …, Harry Ischiropoulos, Joshua D Rabinowitz, Mitchell A Lazar
- Cell, 10.1016/j.cell.2018.06.031
Fear Erasure Facilitated by Immature Inhibitory Neuron Transplantation
- Wu-Zhou Yang, Ting-Ting Liu, Jun-Wei Cao, …, Lin-Yun Liu, Lan Ma, Yong-Chun Yu
- Neuron, 10.1016/j.neuron.2016.11.018
Direct conversion of astrocytes into neuronal cells by drug cocktail
- Lin Cheng, Longfei Gao, Wuqiang Guan, …, Jian Zhao, Yongchun Yu, Gang Pei
- Cell Res, 10.1038/cr.2015.120
Generation of neural progenitor cells by chemical cocktails and hypoxia
- Lin Cheng, Wenxiang Hu, Binlong Qiu, …, Min Wang, Wuzhou Yang, Gang Pei
- Cell Res, 10.1038/cr.2014.32
Activation of aryl hydrocarbon receptor (ahr) by tranilast, an anti-allergy drug, promotes miR-302 expression and cell reprogramming
- Wenxiang Hu, Jian Zhao, Gang Pei
- J Biol Chem, 10.1074/jbc.m113.475624