Inhibiting membrane rupture with NINJ1 antibodies limits tissue injury
- Nobuhiko Kayagaki, Irma B Stowe, Kamela Alegre, …, Joshua D Webster, Ryan L Kelly, Vishva M Dixit
- Nature, 10.1038/s41586-023-06191-5
The road to death: Caspases, cleavage, and pores
- Vishva M Dixit, Vishva M Dixit
- Sci Adv, 10.1126/sciadv.adi2011
Dying cells fan the flames of inflammation
- Kim Newton, Vishva M Dixit, Nobuhiko Kayagaki
- Science, 10.1126/science.abi5934
Shigella ubiquitin ligase IpaH7.8 targets gasdermin D for degradation to prevent pyroptosis and enable infection
- Giovanni Luchetti, Justin L Roncaioli, Roberto A Chavez, …, Nobuhiko Kayagaki, Russell E Vance, Vishva M Dixit
- Cell Host Microbe, 10.1016/j.chom.2021.08.010
Selective activation of PFKL suppresses the phagocytic oxidative burst
- Neri Amara, Madison P Cooper, Maria A Voronkova, …, Matthew Bogyo, Steven T Staben, Vishva M Dixit
- Cell, 10.1016/j.cell.2021.07.004
NINJ1 mediates plasma membrane rupture during lytic cell death
- Opher S Kornfeld, Bettina L Lee, Irma B Stowe, …, Christopher C Goodnow, Edward M Bertram, Vishva M Dixit
- Nature, 10.1038/s41586-021-03218-7
Integration of innate immune signalling by caspase-8 cleavage of N4BP1
- Alexander D Gitlin, Klaus Heger, Alexander F Schubert, …, Joshua D Webster, Kim Newton, Vishva M Dixit
- Nature, 10.1038/s41586-020-2796-5
Paradise revealed III: why so many ways to die? Apoptosis, necroptosis, pyroptosis, and beyond
- Marcelo Pires Amaral, Laura Migliari Branco, Andreas Strasser, Vishva M Dixit, Karina Ramalho Bortoluci
- Cell Death Differ, 10.1038/s41418-020-0526-z
Classification and Nomenclature of Metacaspases and Paracaspases: No More Confusion with Caspases
- Elena A Minina, Jens Staal, Vanina E Alvarez, …, Boris Zhivotovsky, Eric Lam, Peter V Bozhkov
- Mol Cell, 10.1016/j.molcel.2019.12.020
Fiery Cell Death: Pyroptosis in the Central Nervous System
- Brienne A McKenzie, Vishva M Dixit, Christopher Power
- Trends Neurosci, 10.1016/j.tins.2019.11.005
Activity of caspase-8 determines plasticity between cell death pathways
- Kim Newton, Katherine E Wickliffe, Allie Maltzman, …, Meredith S Sagolla, Joshua D Webster, Vishva M Dixit
- Nature, 10.1038/s41586-019-1752-8
Rescue from a fiery death: A therapeutic endeavor
- Nobuhiko Kayagaki, Vishva M Dixit
- Science, 10.1126/science.aaw1177
