Video highlight
Stress-induced metabolic exchanges between complementary bacterial types underly a dynamic mechanism of inter-species stress resistance
- Terry Hwa
- Uwe Sauer
- May 31, 2023
- kedalionlabs.com
- Kapil Amarnath, Avaneesh V Narla, Sammy Pontrelli, …, Uwe Sauer, Otto X Cordero, Terence Hwa
- Nat Commun, 10.1038/s41467-023-38913-8
Greedy reduction of Bacillus subtilis genome yields emergent phenotypes of high resistance to a DNA damaging agent and low evolvability
- Uwe Sauer
- March 15, 2023
- kedalionlabs.com
- Etienne Dervyn, Anne-Gaëlle Planson, Kosei Tanaka, …, Pierre Nicolas, Philippe Noirot, Matthieu Jules
- Nucleic Acids Res, 10.1093/nar/gkad145
Secrets of microbiota drug metabolism
- Uwe Sauer
- February 24, 2023
- kedalionlabs.com
- Andrew J Macpherson, Uwe Sauer, Andrew J Macpherson, …, Uwe Sauer, Andrew J Macpherson, Uwe Sauer
- Nat Med, 10.1038/s41591-023-02227-5
Non-enzymatic acetylation inhibits glycolytic enzymes in Escherichia coli
- Uwe Sauer
- January 14, 2023
- kedalionlabs.com
- Evgeniya Schastnaya, Peter Francis Doubleday, Luca Maurer, …, Peter Francis Doubleday, Luca Maurer, Uwe Sauer
- Cell Rep, 10.1016/j.celrep.2022.111950
Dynamic metabolome profiling uncovers potential TOR signaling genes
- Uwe Sauer
- January 4, 2023
- kedalionlabs.com
- Stella Reichling, Peter F Doubleday, Tomas Germade, …, Robbie Loewith, Uwe Sauer, Duncan Holbrook-Smith
- Elife, 10.7554/elife.84295
Insights into the evolution of enzymatic specificity and catalysis: From Asgard archaea to human adenylate kinases
- Uwe Sauer
- November 4, 2022
- kedalionlabs.com
- Apoorv Verma, Emma Ã…berg-Zingmark, Tobias Sparrman, …, Kwangho Nam, Elisabeth Sauer-Eriksson, Magnus Wolf-Watz
- Sci Adv, 10.1126/sciadv.abm4089
Plasticity of the adult human small intestinal stoma microbiota
- Tobias Fuhrer
- Uwe Sauer
- November 1, 2022
- kedalionlabs.com
- Bahtiyar Yilmaz, Tobias Fuhrer, Deborah Morgenthaler, …, Guido Beldi, Uwe Sauer, Andrew J Macpherson
- Cell Host Microbe, 10.1016/j.chom.2022.10.002
Pharmacological perturbation of thiamine metabolism sensitizes Pseudomonas aeruginosa to multiple antibacterial agents
- Uwe Sauer
- July 28, 2022
- kedalionlabs.com
- Hyung Jun Kim, Yingying Li, Michael Zimmermann, …, Uwe Sauer, Soojin Jang, Kevin Pethe
- Cell Chem Biol, 10.1016/j.chembiol.2022.07.001
Historical contingencies and phage induction diversify bacterioplankton communities at the microscale
- Uwe Sauer
- July 21, 2022
- kedalionlabs.com
- Rachel E Szabo, Sammy Pontrelli, Jacopo Grilli, …, Shaul Pollak, Uwe Sauer, Otto X Cordero
- Proc Natl Acad Sci U S A, 10.1073/pnas.2117748119
Correction: Niche partitioning facilitates coexistence of closely related honey bee gut bacteria
- Uwe Sauer
- April 1, 2022
- kedalionlabs.com
- Silvia Brochet, Andrew Quinn, Ruben A T Mars, Nicolas Neuschwander, Uwe Sauer, Philipp Engel
- Elife, 10.7554/elife.78825
Metabolic reprogramming of Pseudomonas aeruginosa by phage-based quorum sensing modulation
- Uwe Sauer
- February 16, 2022
- kedalionlabs.com
- Hanne Hendrix, Maria Zimmermann-Kogadeeva, Michael Zimmermann, …, Jean-Paul Noben, Abram Aertsen, Rob Lavigne
- Cell Rep, 10.1016/j.celrep.2022.110372
Extensive regulation of enzyme activity by phosphorylation in Escherichia coli
- Uwe Sauer
- September 25, 2021
- kedalionlabs.com
- Evgeniya Schastnaya, Zrinka Raguz Nakic, Christoph H Gruber, …, Jimin Park, Harris H Wang, Uwe Sauer
- Nat Commun, 10.1038/s41467-021-25988-4
Dynamic Connection between Enzymatic Catalysis and Collective Protein Motions
- Uwe Sauer
- July 12, 2021
- kedalionlabs.com
- Pedro Ojeda-May, Ameeq Ui Mushtaq, Per Rogne, …, Uwe H Sauer, Magnus Wolf-Watz, Kwangho Nam
- Biochemistry, 10.1021/acs.biochem.1c00221
Conservation of metabolic regulation by phosphorylation and non-covalent small-molecule interactions
- Uwe Sauer
- May 18, 2021
- kedalionlabs.com
- Christoph H Gruber, Maren Diether, Uwe Sauer
- Cell Syst, 10.1016/j.cels.2021.04.009
Salt-Tolerant Metabolomics for Exometabolomic Measurements of Marine Bacterial Isolates
- Uwe Sauer
- May 4, 2021
- kedalionlabs.com
- Sammy Pontrelli, Uwe Sauer
- Anal Chem, 10.1021/acs.analchem.0c04795
Cooperation and Cheating among Germinating Spores
- Uwe Sauer
- September 25, 2020
- kedalionlabs.com
- Samay Pande, Pau Pérez Escriva, Yuen-Tsu Nicco Yu, Uwe Sauer, Gregory J Velicer
- Curr Biol, 10.1016/j.cub.2020.08.091
Bacterial Glycogen Provides Short-Term Benefits in Changing Environments
- Uwe Sauer
- March 1, 2020
- kedalionlabs.com
- Karthik Sekar, Stephanie M Linker, Jen Nguyen, Alix Grünhagen, Roman Stocker, Uwe Sauer
- Appl Environ Microbiol, 10.1128/aem.00049-20
Synthesis of Densely Functionalized N -Alkenyl 2-Pyridones via Benzyne-Induced Ring Opening of Thiazolino-Fused 2-Pyridones
- Uwe Sauer
- August 17, 2019
- kedalionlabs.com
- Pardeep Singh, Andrew G Cairns, Dan E Adolfsson, Jörgen Ådén, Uwe H Sauer, Fredrik Almqvist
- Org Lett, 10.1021/acs.orglett.9b02549
Regulatory mechanisms underlying coordination of amino acid and glucose catabolism in Escherichia coli
- Uwe Sauer
- July 28, 2019
- kedalionlabs.com
- Mattia Zampieri, Manuel Hörl, Florian Hotz, Nicola F Müller, Uwe Sauer
- Nat Commun, 10.1038/s41467-019-11331-5
(p)ppGpp Regulates a Bacterial Nucleosidase by an Allosteric Two-Domain Switch
- Uwe Sauer
- April 27, 2019
- kedalionlabs.com
- Yong Everett Zhang, René Lysdal Bærentsen, Tobias Fuhrer, Uwe Sauer, Kenn Gerdes, Ditlev Egeskov Brodersen
- Mol Cell, 10.1016/j.molcel.2019.03.035
Editorial overview: Current Opinion in Microbiology 2018 Special issue ‘Microbial systems biology, vol. 45’
- Uwe Sauer
- October 22, 2018
- kedalionlabs.com
- Terry Hwa, Uwe Sauer
- Curr Opin Microbiol, 10.1016/j.mib.2018.09.005