Metabolic modelling-based in silico drug target prediction identifies six novel repurposable drugs for melanoma
- Tamara Bintener, Maria Pires Pacheco, Demetra Philippidou, …, Stephanie Kreis, Dagmar Kulms, Thomas Sauter
- Cell Death Dis, 10.1038/s41419-023-05955-1
Ambra1 modulates the tumor immune microenvironment and response to PD-1 blockade in melanoma
- Alex Frias, Luca Di Leo, Asier Antoranz, …, Francesco Cecconi, Francesca Maria Bosisio, Daniela De Zio
- J Immunother Cancer, 10.1136/jitc-2022-006389
Expanding the Disease Network of Glioblastoma Multiforme via Topological Analysis
- Apurva Badkas, Sébastien De Landtsheer, Thomas Sauter, …, Apurva Badkas, Sébastien De Landtsheer, Thomas Sauter
- Int J Mol Sci, 10.3390/ijms24043075
scFASTCORMICS: A Contextualization Algorithm to Reconstruct Metabolic Multi-Cell Population Models from Single-Cell RNAseq Data
- Maria Pires Pacheco, Jimmy Ji, Tessy Prohaska, …, Tessy Prohaska, MarÃa Moscardó GarcÃa, Thomas Sauter
- None, 10.3390/metabo12121211
EGFR-induced suppression of HPV E6/E7 is mediated by microRNA-9-5p silencing of BRD4 protein in HPV-positive head and neck squamous cell carcinoma
- Danupon Nantajit, Luana Presta, Thomas Sauter, …, Luana Presta, Thomas Sauter, Mahvash Tavassoli
- Cell Death Dis, 10.1038/s41419-022-05269-8
Drug Target Prediction Using Context-Specific Metabolic Models Reconstructed from rFASTCORMICS
- Tamara Bintener, Maria Pires Pacheco, Ali Kishk, Jeff Didier, Thomas Sauter
- Methods Mol Biol, 10.1007/978-1-0716-2513-2_17
The gut microbial metabolite formate exacerbates colorectal cancer progression
- Dominik Ternes, Mina Tsenkova, Vitaly Igorevich Pozdeev, …, Serge Haan, Paul Wilmes, Elisabeth Letellier
- Nat Metab, 10.1038/s42255-022-00558-0
Bruceine D Identified as a Drug Candidate against Breast Cancer by a Novel Drug Selection Pipeline and Cell Viability Assay
- Claudia Cipriani, Maria Pires Pacheco, Ali Kishk, …, Daniel Abankwa, Elisabeth Schaffner-Reckinger, Thomas Sauter
- None, 10.3390/ph15020179
Mechanistically Coupled PK (MCPK) Model to Describe Enzyme Induction and Occupancy Dependent DDI of Dabrafenib Metabolism
- Marco Albrecht, Yuri Kogan, Dagmar Kulms, Thomas Sauter
- None, 10.3390/pharmaceutics14020310
Project-based learning course on metabolic network modelling in computational systems biology
- Thomas Sauter, Tamara Bintener, Ali Kishk, …, Thomas Pfau, Patricia Martins Conde, Maria Pires Pacheco
- PLoS Comput Biol, 10.1371/journal.pcbi.1009711